Food allergy: A practice parameter update—2014 - aaaai.org

1 practice parameter Food allergy: A practice parameter update 2014. Hugh A. Sampson, MD, Seema Aceves, MD, PhD, S. Allan Bock, MD, John James, MD, Stacie Jones, MD, David Lang, MD, Kari Nadeau, MD, PhD, Anna Nowak-Wegrzyn, MD, John Oppenheimer, MD, Tamara T. Perry, MD, Christopher Randolph, MD, Scott H. Sicherer, MD, Ronald A. Simon, MD, Brian P. Vickery, MD, and Robert Wood, MD. Chief Editors : Hugh A. Sampson, MD, and Christopher Randolph, MD. Members of the Joint Task Force on practice Parameters : David Bernstein, MD, Joann Blessing-Moore, MD, David Khan, MD, David Lang, MD, Richard Nicklas, MD, John Oppenheimer, MD, Jay Portnoy, MD, Christopher Randolph, MD, Diane Schuller, MD, Sheldon Spector, MD, Stephen A.

2 Tilles, MD, and Dana Wallace, MD. practice parameter Workgroup : Hugh A. Sampson, MD (Chair), Seema Aceves, MD, PhD, S. Allan Bock, MD, John James, MD, Stacie Jones, MD, David Lang, MD, Kari Nadeau, MD, PhD, Anna Nowak-Wegrzyn, MD, John Oppenheimer, MD, Tamara T. Perry, MD, Christopher Randolph, MD, Scott H. Sicherer, MD, Ronald A. Simon, MD, Brian P. Vickery, MD, and Robert Wood, MD. This parameter was developed by the Joint Task Force on Because this document incorporated the efforts of many practice Parameters, representing the American Academy of participants, no single individual, including those who served on Allergy, Asthma & Immunology ( aaaai ); the American the Joint Task Force, is authorized to provide an official aaaai .

3 College of Allergy, Asthma & Immunology (ACAAI); and the or ACAAI interpretation of these practice parameters. Any Joint Council of Allergy, Asthma & Immunology (JCAAI). The request for information about or an interpretation of these aaaai and the ACAAI have jointly accepted responsibility practice parameters by the aaaai or ACAAI should be for establishing Food Allergy: A practice parameter update directed to the Executive Offices of the aaaai , ACAAI, and 2014.'' This is a complete and comprehensive document at the JCAAI. These parameters are not designed for use by current time.

4 The medical environment is a changing one, and pharmaceutical companies in drug promotion. (J Allergy Clin not all recommendations will be appropriate for all patients. Immunol 2014;134:1016-25.). Disclosure of potential conflict of interest: H. A. Sampson has received research support of the Board of Regents for the American College of Allergy, Asthma & Immunology from the National Institute of Allergy and Infectious Diseases (NIAID; AI44236 and (ACAAI); has consultant arrangements with AstraZeneca and Genentech; has received AI66738), the National Institutes of Health (NIH; RR026134), and Food Allergy payment for lectures from GlaxoSmithKline, AstraZeneca, Genentech, and TEVA.

5 Research and Education (FARE); has received travel support as the chair of PhARF and has received travel support from TEVA. S. H. Sicherer has received research sup- Award review committee; has consultant arrangements with Allertein Therapeutics, port from the NIAID, is a member of the American Board of Allergy and Immunology, Regeneron, and the Danone Research Institute; and has received payment for lectures has consultant arrangements with Novartis and FARE; and receives royalties from from Thermo Fisher Scientific, UCB, and Pfizer. S. Aceves is a member of the medical UpToDate.

6 R. A. Simon has provided expert testimony for various law firms; has advisory panel for the American Partnership for Eosinophilic Disorders; has received received payment for lectures from Merck, Novartis, and CSL-Behring; holds patents research support from the National Institutes of Health (NIAID AI092135), the Depart- for the use of surfactants in chronic rhinosinusitis and asthma; has received royalties ment of Defense, and the American Academy of Allergy, Asthma & Immunology from Wiley Blackwell and UpToDate; and has stock options in URXmobile. ( aaaai )/American Partnership for Eosinophilic Disorders; has a patent held by Uni- B.

7 P. Vickery has received research support from the NIH/NIAID (AI099083) and versity of California San Diego for OVB licensed to Meritage Pharma; and has the Foundation of the ACAAI. R. Wood has consultant arrangements with the Asthma received travel support from the NIH and the Falk Foundation. S. A. Bock is on the and Allergy Foundation of America, is employed by Johns Hopkins University, has medical advisory board for FARE. S. Jones has received research support from the received research support from the NIH, and receives royalties from UpToDate. The NIH (COFAR), the NIH/NIAID Immune Tolerance Network (A1-15416), and Food rest of the authors declare that they have no relevant conflicts of interest.

8 Allergy Research and Education. D. Lang is a speaker for Genentech/Novartis, We thank Anne Munoz-Furlong for review and helpful comments to Section IX: GlaxoSmithKline, and Merck; has consultant arrangements with GlaxoSmithKline, Management in special settings.''. Merck, Aerocrine; and has received research support from Genentech/Novartis and Corresponding author: Susan L. Grupe, Joint Task Force on practice Parameters, 50 N. Merck. A. Nowak-Wegrzyn is a speaker for Thermo Fisher Scientific, is on the advi- Brockway St, #304, Palatine, IL 60067. E-mail: sory board for Nutricia, is on the Data Safety Monitoring Board for Merck, and has Received for publication February 7, 2014; revised May 2, 2014; accepted for publication received research support from Nestl e (grant 0955), Nutricia, and the NIH.

9 J. May 6, 2014. Oppenheimer has received research support from AstraZeneca, GlaxoSmithKline, Available online August 28, 2014. Merck, Boehringer Ingelheim, Novartis, and MedImmune; has provided legal 0091-6749/$ consultation/expert witness testimony in malpractice defense cases; is chairman of 2014 American Academy of Allergy, Asthma & Immunology the American Board of Allergy and Immunology; and has consultant arrangements with GlaxoSmithKline, Mylan, Novartis, and Sunovion. C. Randolph is a member 1016. J ALLERGY CLIN IMMUNOL SAMPSON ET AL 1017. VOLUME 134, NUMBER 5. Key words: Food allergy, food allergen, cross-reactivity, David M.

10 Lang, MD. adverse food reactions, IgE-mediated food allergy, eosinophilic Allergy/Immunology Section esophagitis Respiratory Institute Allergy and Immunology Fellowship Training Program Cleveland Clinic Foundation Previously published practice parameters of the Joint Task Cleveland, Ohio Force on practice Parameters for Allergy and Immunology are available at or Richard A. Nicklas, MD. Department of Medicine George Washington Medical Center Washington, DC. CONTRIBUTORS. The Joint Task Force has made a concerted effort to acknowl- John Oppenheimer, MD. edge all contributors to this parameter .