Guide to Receiving, Storing, and Handling Vaccines

1 Guide to receiving , storing , and Handling Vaccines yy This Guide is not a substitute for the package insert included with each vaccine . yy Visually inspect Vaccines for floating particles and/or discoloration before administration. yy Keep Vaccines in their original boxes to protect them from exposure to light (which can affect potency) and to help keep them organized. yy Open multi-dose vials can be used until the expiration date on the vial, unless contaminated. receiving storing Handling vaccine Arrival condition Storage requirements Preparing/reconstituting Shelf life after opening/reconstituting Diphtheria, tetanus, Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after pertussis (DTaP) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after Daptacel, Infanrix packs in summer Don't expose to temperatures don't use if they don't dissolve.

2 Placing needle on pre-filled Never frozen 32 F or below. syringe. Tetanus, diphtheria Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after (DT, Td, ) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after DT generic, Td generic, packs in summer Don't expose to temperatures don't use if they don't dissolve placing needle on pre-filled Decavac Never frozen 32 F or below. syringe. Multi-dose vials: refrigerate unused portions. May be used until expired, unless contaminated. DTaP HepB IPV Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after Pediarix packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after packs in summer Don't expose to temperatures don't use if they don't dissolve.

3 Placing needle on pre-filled Never frozen 32 F or below. syringe. Use until expiration date noted on vial, unless contaminated. DTaP IPV Hib Packed with refrigerator Refrigerate immediately at Reconstitute just before using. Administer immediately after Pentacel packs in winter OR frozen 35 to 46 F (2 to 8 C). Gently shake vial of liquid withdrawal from the vial. packs in summer Don't expose to temperatures DTaP-IPV and withdraw entire Discard if not used within 30. Never frozen 32 F or below. contents. minutes of reconstitution. Protect both diluent and Inject DTaP-IPV into the vial powder from exposure to light of ActHIB powder and shake ( , store in original box). well. Withdraw entire contents, about mL.. Immunization Program Box 64975. St. Paul, MN 55164-0975. 651-201-5503, 1-800-657-3970. Page 1 of 7 (10/13). receiving storing Handling vaccine Arrival condition Storage requirements Preparing/reconstituting Shelf life after opening/reconstituting DTaP IPV Packed with refrigerator Refrigerate immediately at Shake vial well before use.

4 Administer immediately after Kinrix packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after packs in summer Don't expose to temperatures don't use if they don't dissolve. placing needle on pre-filled Never frozen 32 or below. syringe. Use until expiration date noted on vial, unless contaminated. Tetanus, diphtheria, Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after pertussis (Tdap) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after Adacel, Boostrix packs in summer Don't expose to temperatures don't use if they don't dissolve. placing needle on pre-filled Never frozen 32 or below. syringe. Haemophilus influenzae Packed with refrigerator Refrigerate immediately at Use only diluent supplied with Administer immediately after type b (Hib) packs in winter OR frozen 35 to 46 F (2 to 8 C).

5 ActHIB or Hiberix. drawing up in syringe. ActHIB packs in summer Don't expose to temperatures Reconstitute ActHIB or Use ActHIB and Hiberix Hiberix 32 or below. PedvaxHIB. Never frozen Hiberix just before using. within 24 hours of Protect from exposure to light Inject the entire volume of the reconstitution when stored in ( , store in original box). diluent into the vial of vaccine . refrigerator. Diluent: may be refrigerated or Shake well. stored at room temperature 68 Withdraw entire volume of to 77 F (20 to 25 C). reconstituted ActHIB or mL Hiberix. Hepatitis A Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after (Hep A) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after Havrix, Vaqta packs in summer Don't expose to temperatures don't use if they don't dissolve. placing needle on pre-filled Never frozen 32 or below.

6 Syringe. Hepatitis B Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after (HepB) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after Engerix-B, Recombivax HB packs in summer Don't expose to temperatures don't use if they don't dissolve. placing needle on pre-filled Never frozen 32 or below. syringe. HepA HepB Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after Twinrix packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after packs in summer Don't expose to temperatures don't use if they don't dissolve. placing needle on pre-filled Never frozen 32 or below. syringe. Use until expiration date noted on vial, unless contaminated. Hib HepB Packed with refrigerator Refrigerate immediately at Shake vial well before use.

7 Use until expiration date Comvax packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; noted on vial, unless packs in summer Don't expose to temperatures don't use if they don't dissolve. contaminated. Never frozen 32 or below. MDH, Immunization Program Page 2 of 7 (10/13). receiving storing Handling vaccine Arrival condition Storage requirements Preparing/reconstituting Shelf life after opening/reconstituting Human papillomavirus Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after (HPV) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe. Cervarix, Gardasil packs in summer Don't expose to temperatures don't use if they don't dissolve. Discard if not used by end of Never frozen 32 F or below. workday. Protect from exposure to light ( , store in original box).

8 Polio, inactivated Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after vaccine (IPV) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; drawing up in syringe or after Ipol packs in summer Don't expose to temperatures don't use if they don't dissolve. placing needle on pre-filled Never frozen 32 F or below. syringe. Multi-dose vials: refrigerate unused portions. May be used until expired, unless contaminated. Influenza, inactivated Packed with refrigerator Refrigerate immediately at Shake vial well before use. Administer immediately after (IIV) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; withdrawing from the vial or Afluria, Agriflu, Fluarix, packs in summer Don't expose to temperatures don't use if they don't dissolve. after placing needle on pre- Flublok, Flucelvax, Flulaval, Never frozen 32 F or below.

9 Filled syringe. Fluvirin, Fluzone Multi-dose vials: refrigerate Protect Fluarix,Flulaval, Flucelvax, and Flublok from unused portions. May be used until expired, unless exposure to light ( , store in contaminated. original box). For use during current flu season; check expiration dates. Influenza, live May arrive frozen or partially Refrigerate immediately at Remove the rubber tip Administer immediately attenuated (LAIV) frozen 35 to 46 F (2 to 8 C). protector from the sprayer. after removing from the Flumist Packed with refrigerator Don't store in the freezer. Deliver dose into one refrigerator. packs Don't expose to temperatures nostril. For use during current flu 32 F or below. Remove the dose-divider clip season; check expiration dates. and deliver the remaining Note: shelf life is 18 weeks dose into the other nostril. (4 months). Japanese Encephalitis Packed with refrigerator Refrigerate immediately at Shake vial well before use.

10 Administer immediately after (JE) packs in winter OR frozen 35 to 46 F (2 to 8 C). Look for floating particles; reconstitution. Ixiaro packs in summer Don't expose to temperatures don't use if they don't dissolve Use within 8 hours after Never frozen 32 F or below. reconstitution. Protect from exposure to light ( , store in original box). MDH, Immunization Program Page 3 of 7 (10/13). receiving storing Handling vaccine Arrival condition Storage requirements Preparing/reconstituting Shelf life after opening/reconstituting Measles, mumps, Packed with refrigerator Refrigerate immediately at Reconstitute just before using. Administer immediately after rubella (MMR) packs 35 to 46 F (2 to 8 C) OR Use only the diluent supplied withdrawal from the vial. M-M-R II freeze below 5 F (-15 C). with the vaccine . Use within 8 hours of MDH recommends storing Inject the entire volume of the reconstitution when stored MMR in the freezer, not the diluent into the vial of vaccine in refrigerator and protected refrigerator.