High Performance Contact Shock Freezers - Polestar Cooling

1 High Performance Contact Shock FreezersBiomedical Refrigeration I MBF-30 CTechnology for 110/09/08 17:35:39 Horizontal Contact Shock freezing technology for blood plasma , biological and pharmaceutical preparations. Utility model registered DE 203 03 Patent pending PCT/EP2004/001634 Safety of law and compliance with directives for the preparation of blood plasma storage at a core tempera-ture of < -30 CHigh Performance Contact Shock Freezerss &AST FREEZING TO CORE TEMPERATURE OF #s !UTOMATED AND TRANSPARENT FREEZING PROCESS INCLUSIVE documentations 3 IMPLE AND TRANSPARENT FREEZING PROCESS INCLUSIVE documentations 3 IMPLE AND INTUITIVE OPERATIONs %VENLY SHAPED BAGS FOR OPTIMUM UTILIZATION OF STORAGE options, improved readability of labels and barcodes, improved mechanical further processing in automated systemss 3 HOCK FREEZING OF SEVERAL BATCHES IN SUCCESSION WITH-out intermediate defrosting)s 3 TATE OF THE ART COMPRESSOR TECHNOLOGY WITH OPTI-mized Cooling systemss !

2 IR COOLED CONDENSER -"& -"& OR OPTIONAL WATER Cooling -"& 7 s !IR COOLED CONDENSER AND COMPRESSOR AS EXTERNAL UNIT -"& 3 -"& 3 OR OPTIONAL WATER Cooling -"& 7 s 2 EFRIGERANT FREE FROM #&# AND (#&#s 3 EPARATE REFRIGERATION OF THE lXED COVER PLATE AND THE ELECTRICALLY ADJUSTABLE WORKING SURFACE -"& -"& s 3 EPARATE FREEZING OF THE ELECTRICALLY ADJUSTABLE COVER PLATE AND THE lXED WORKING SURFACE OF THE UPPER TABLE AS WELL AS SEPARATE FREEZING OF THE lXED COVER PLATE and the electrically adjustable working surface of the LOWER TABLE -"& s 1 UICK AND EASY LOADING REMOVAL OF PREPARATIONSs %RGONOMIC DESIGNs 4HE PRESET AND OPERATING TEMPERATURE SET POINT OF -50 C minimizes the risk of bags rupturings -OBILITY BY MEANS OF HEAVY CASTORS WITH BRAKES STAND-ARD EQUIPMENT FOR -"& AND -"& MODELS s (IGH GRADE STAINLESS STEEL HOUSINGs Compact, service- and maintenance-friendly construction.))

3 Easy cleaning and disinfections ,OWER SURFACE AREA AND LOWER AREA LOAD REQUIREMENTSs $ELIVERED READY FOR USE PH 6 (Z ! n STANDARD MODELS -"& Advantages of the horizontal Contact Shock freezing technologyT V RheinlandREINRAUMKLASSIFIZIERUNGCLEAN ROOM CLASSIFICATION gepr fteSicherheitDIN EN ISO 9001: 2000 und DIN EN ISO 140001 Zertifikate Nr 09 100 6858 und 01 104 031880 CFC & HCFC 210/09/08 17:35:45 The MBF 12 is installed as a free-standing, plug and play air-cooled 12 Freeze diagramContact operating plateadjustable, separatlycontrolledContact cover platel XED SEPARATLY CONTROLLEDP rinciple / Mode of operationControl elementsDummy-/referencebag port)-!'/ -ULTI CHANNEL 0 ROCESSand Program ControllerEmergencybutton/PENtable-AIN SWITCHA rrangement possibilities12 PlasmabagsAT ML EACH CONTENT ML 3 rows at 4 bags eachClose Table-ODE SWITCHh/PERATING 310/09/08 17:35:56 Installation Instructions:4HE INSTALLATION COSTS FOR UNITS WITH AN EXTERNAL AIR COOL ing system or water-cooled system are not included in THE UNIT PRICE STANDARD VERSION 4 HESE COSTS ARE SUBJECT to an individual client request and can vary dependant on the conditions in the designated MBF 21 is installed as a free-standing, air-cooled unit ready for REQUEST THE MBF 21 can also be equipped with the following Cooling systems.

4 S %XTERNAL AIR Cooling SYSTEM SEE OPTIONS PICTURE s 7 ATER Cooling SYSTEM SEE OPTIONS PICTURE - Directly connected to the in-house water system - Connected to a separate closed air-conditioning sys-TEM ALSO CALLED h! # WATER Cooling SYSTEMv - Connected to a separate closed water circuit, also called refrigerated water tower Freeze diagramArrangement possibilities21 Plasmabagsat 500 ml each CONTENT ML 3 rows at 4 bags eachControl elementsDummy-/referencebag port)-!'/ -ULTI CHANNEL 0 ROCESSand Program ControllerEmergencybutton/PENtable-AIN SWITCHC ontact operating plate adjustable, separatly controlledContact cover plate l XED SEPARATLY controlledPrinciple / Mode of operationMBF 21 Close Table-ODE SWITCHh/PERATING 410/09/08 17:36:07 Installation Instructions:4HE INSTALLATION COSTS FOR UNITS WITH AN EXTERNAL air Cooling system or water-cooled system are NOT INCLUDED IN THE UNIT PRICE STANDARD VERSION These costs are subject to an individual client request and can vary dependant on the condi-tions in the designated 42 The following Cooling systems for the condenser are possible.

5 S %XTERNAL AIR Cooling SYSTEM SEE OPTIONS PICTURE s 7 ATER Cooling SYSTEM SEE OPTIONS PICTURE - Directly connected to the in-house water system - Connected to a separate closed air-conditioning sys-TEM ALSO CALLED h! # WATER Cooling SYSTEMv - Connected to a separate closed water circuit, also called refrigerated water tower Freeze diagramControl elements3 WITCH v%CO -ODEfor top/bottom level 3 WITCH v/PERATING -ODE FORtop/bottom level Close the tabledepending on switch position - top - bottom/PEN THE TABLE depending on switch position - top - bottomSensor port fordummy/ reference bag LOWER UPPER LEVEL -AIN SWITCH)-!'/ -ULTI CHANNEL 0 ROCESSand temparature Controller21 Plasmabagsat 500 ml each CONTENT ML 3 rows at 4 bags eachArrangement possibilities PER LEVEL Principle /Mode of operationUpper tableContact cover plateadjustable, separatly controlledContact operating platel XED SEPARATLY CONTROLLEDL ower tableContact cover platel XED SEPARATLY CONTROLLEDC ontact operating plateadjustable, separatly controlledMBF 510/09/08 17:36.

6 20 Subject to change without prior DataFreezing capacity12 plasma bags at 500 ml each (content 450 ml)21 plasma bags at 500 ml each (content 450 ml)42 (2 x 21) plasma bags at 500 ml each (content 450 ml)Freezing time, depending on load & ambient temperature30 - 60 min30 - 60 min30 - 60 minFreezing time to core temperature of -30 C for plasma bags of 500 ml each (content 450 ml)12 units ~ 40 min21 units ~ 40 min42 units ~ 40 minExternal dimensions (H x W x D)1600 x 970 x 770 mm1600 x 1470 x 770 mm1920 x 2050 x 770 mmDimensions Contact plates / working surface (W x D)490 x 640 mm970 x 6202 units of 970 x 620 Operating temperature (preset), reached within ~ 20min(pre- Cooling phase)-50 C UPPER LOWER Contact PLATE -50 C UPPER LOWER Contact PLATE -50 C UPPER LOWER Contact PLATE Operation and control panel via control and recording unitIMAGO 500 (multi-channel process & program controler)WITH COLOR DISPLAY COLORS IMAGO 500 (multi-channel process & program controler)WITH COLOR DISPLAY COLORS IMAGO 500 (multi-channel process & program controler)WITH COLOR DISPLAY COLORS Defrosting (manual via mode switch "Operating Mode")Hot gasHot gasHot gasDefrosting time (duration), as preset safety factor8 min8 min8 minCompressorBitzerBitzer2 x BitzerRefrigerant TypeR507R507R507 Net weight (with standard equipment)300 kg400 kg400 kg*Climate class (ambient temperature range)N (+16 C to +32 C)N (+16 C to +32 C)N (+16 C to +32 C)Relative humidity (at +32 C ambiant temperature)b 70%b 70%b 70%Voltage (3ph)3~400V / 50 Hz (16A)3~400V / 50 Hz (16A)

7 3~400V / 50 Hz (32A)Power1800 W3000 W6000 WEnergy consumption4 kWh / freezing cycle6 kWh / freezing cycle6 kWh / freezing cycle / levelSafety classIIIM aterial outer casingstainless steel steel steel directive2004/108/EEC2004/108/EEC2004/10 8/EECLow voltage directive2006/95/EEC2006/95/EEC2006/95/E ECGMP - clean room classifi cationclass ISO 5/EC GMP Aclass ISO 5/EC GMP Aclass ISO 5/EC GMP AGMP - clean room classifi cation, with external water Cooling -class ISO 6/EC GMP Bclass ISO 6/EC GMP BEquipment & OptionsControl and operating components integrated -Control and operating components as external unit-- Eco mode (interim storage temperature of -37 C) Dummy / reference bag port for accompanying coretemperature readings during the freezing process 1 x 1 x 2 x Dummy / reference bag (incl. sensor)For dummy bag port For dummy bag port For dummy bag port Dummy / reference bag500 ml 500 ml 500 ml Transport carrier- 1 1 Transport tray, recommended-44 Interface / interface card Software for IMAGO 500, Analyting software (PCA 3000) Barcode reader & software (real time) with dongle (SVS 2000)Preinstalled PC with SVS 2000 and barcode readerIntegrated air-cooled condenser -Air-cooled condensers and compressors as external units(850 x 1500 x 760 mm each)

8 -1 external unit MBF 21 S 2 external unit MBF 42 S Water Cooling via in-house / site water supply-MBF 21 W MBF 42 W Smooth castors with stabilizers -Securing feet with models with condensers and compressors as external units-MBF 21 S MBF 42 S Wooden packaging for ocean transport / export MBF 12 MBF 21 MBF 42 standard / optional / - not available - All values were measured at +25 C ambient temperature* without external 610/09/08 17:36:29 Transport carrier & transport tray Dummy / reference bag 500 ml CONTENT ML Dummy / reference bag INCL SENSOR CABLE Barcode reader OPTIONAL 2 External WaterCooling1 Example of an external installation of the Cooling system: STANDARD AT -"& 3 AND -"& 3 Equipment / 710/09/08 17:36:59 DMN - Dometic Monitoring NetworkDMN is a universal software to gather, display and monitor tem-perature data (graphically illustrated) with an activity history for all appliance components.

9 In case of power failure, temperature alarms, door opening alarms, etc., the software forwards the alarm messages directly via mail or SMS to the person in connection to a third-party appliance is possible via network - module4HE NEWLY DEVELOPED -"& MODULE ALLOWS s Collection of plasma bags by means of a barcode scanners Creation of bag groups (lots) that can be assigned to Freezers and processess Recording of the freezing processs Process data are recorded in the DMN data base and cannot be manipulateds Only successfully completed freezing data are recordeds Complete traceability of frozen bagsTechnology for lifeDometic S. Medical Systems /P DER (EI , (OSINGEN ,UXEMBOURG4EL &AX - 810/09/08 17:37:14))