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HILIC Separations Technical Guide - Thermo Fisher Scientific
The HILIC mode of separation can be traced back to 1951, when Gregor et al. [2] described a water-enriched layer on an ion-exchange resin surface. The following year, Samuelson and Sjöström analyzed monosaccharides on an ion-exchange column [3]. Then, in 1954, Rückert and Samuelson [4] postulated
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