I Introduction II G Protein-coupled Receptors III Receptor ...
• The enzyme phosphorylase catalyzes glycogen breakdown, while glycogen synthase catalyzes polymerization. • Regulation is achieved by several hormones, such as glucagon (from the pancreas) and epinephrine (from the adrenal medulla). Binding of epinephrine or glucagon to their receptors activates adenyl cyclase. cAMP binds to the regulatory ...
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Metabolism Lecture 7 — METABOLIC_REGULATION— Restricted for students enrolled in MCB102, UC Berkeley, Spring 2008 ONLY Phases of the TCA Cycle.  Acetyl-CoA production: Organic fuels Acetyl-CoA  Acetyl-CoA oxidation: Acetyl-CoA enters TCA and is enzymatically oxidized, but energy is conserved in electron carriers, NADH FADH 2
The cyclic-AMP (cAMP) cascade begins with the production of cAMP, which is a pure signaling molecule, i.e., not a metabolism intermediate. cAMP binds and activates protein kinase A (PKA). PKA converts phosphorylase-b into phosphorylase-a, which is phosphorylated and active, in two steps. PKA converts glycogen
The “committed step”: fructose 6-phosphate fructose 1,6-bisphosphate. Two triose compounds are isomerized and oxidized to retrieve ATP & NADH via glyceraldehydes 3-phosphate dehydrogenase. The pathway concludes with a strong, irreversible, ATP …
Metabolism Lecture 5 — PENTOSE PHOSPHATE PATHWAY — Restricted for students enrolled in MCB102, UC Berkeley, Spring 2008 ONLY Oxidative Phase: Glucose-6-P Ribose-5-P Glucose 6-phosphate dehydrogenase.
A quick guide to sketching phase planes Section 6.1 of the text discusses equilibrium points and analysis of the phase plane. However, there is one idea, not mentioned in the book, that is very useful to sketching and analyzing phase planes, namely nullclines. Recall the basic setup for an autonomous system of two DEs: dx dt = f(x,y) dy dt = g(x,y)
Practice problems (with answers) This is the degree of difficulty of the questions that will be on the test. This is not a practice test because I did not consider how long it would take to finish these problems. It also does not have a matching section, which I will include on the test. 1. DNA polymorphisms on the Y chromosome and on mtDNA ...
RJ-45 connectors intended for CAT-5 cable to attach properly to CAT-6 cable. When you're shopping for RJ-45 connectors, make sure the ones you buy are suitable for CAT-6. The picture below shows a CAT-5 and a CAT-6 connector the CAT-6 connector is the darker one).
activator of PFK, the glycolytic enzyme. Regulation of pyruvate kinase • If glycolysis gets past the phosphofructokinase step, then regulation is at the pyruvate kinase step. • Pyruvate kinase activity is inhibited under low glucose conditions by covalent phosphorylation • If fructose 1,6 bisphosphate is formed, it acts a allosteric feed-
This regulatory enzyme contains two distinct enzyme activities in two active sites on one single polypeptide chain. FPK-2 gets phosphorylated in the cAMP cascade in the liver. The effect of phosphorylation generally depends on the enzyme, but usually activity either goes up or down. When this giant
chemical kinetics, providing rate laws for biochemical processes (i.e. enzyme-catalysed reactions and cooperative binding). An optional section treats common approximation methods. Chapter 4 introduces techniques for analysis of diﬀerential equation models, including phase plane analysis, stability, bifurcations, and sensitivity analysis.