Indena's International Product List

1 PRODUCTLISTAt Indena we believe that an in-depth knowledge in active ingredients derived from botanicals and the search for excellence at all times are crucial commitments to serving our customers in pharmaceuticals, health-foods, foods and personal and production technologies are the main focus of our mission and the way we create a value difference for our partners. And we ve got almost 100 years of experience to prove in botanical derivativesOUR MISSIONThe ingredients described herein are offered for consideration for use in health-food, common food, pharmaceuticals and personal ingredients DISCLAIMERSPERSONAL CARE ingredients DISCLAIMERThe ingredients described herein are offered for consideration for use in personal care products.

2 The information provided describes historical use, ingredient activity and other information that may be relevant to their use in such products. How each ingredient would contribute to a particular Product would be formulation specific. Furthermore please note that this documentation is available for various countries all over the world and hence it may contain statements not applicable to your s Active Pharmaceutical ingredients are produced in compliance with cGMPs and in pharmaceutical inspected plants, supported by s Personal Care ingredients are REACH registeredPERSONAL CAREI ndena s ingredients for food supplements are produced under Hazard Analysis and Crytical Control Points (HACCP) and in compliance with Food Safety Modernization Act (FSMA)

3 HEALTH - FOODTHE QUALITYFOOD & FLAVOURSB otanical extracts with organoleptic propertiesHALAL certifiedKOSHER certifiedCEP grantedCGGRAS: the Product can be used as an ingredient in common food (US) ECOCERT validatedECOSMOS validatedCoPlease note this documentation is available for various Countries all over the world and hence it may contain statements or Product classification not applicable to your Country. The claims made are in reference to ingredients only, hence they do not refer to finished products and they may not comply with Regulation EC n. 1924/2006 or other provisions in place in your Country. These statements have not been evaluated by the Food and Drug Administration.

4 These products are not intended to diagnose, treat, cure or prevent any disease. Marketers of any finished Product containing any ingredient are responsible for ensuring compliance with all applicable laws and regulations of Countries where the finished Product is IS A REGISTERED TRADEMARKINDENARESEARCHES,DEVELOPS andMARKETSACTIVEPRINCIPLESand INGREDIENTSDERIVED FROMMEDICINAL and EDIBLEPLANTS06 PURE MOLECULES ISOLATED OR derived FROM PLANTSISOLATED or SEMISYNTHETIC PURE PRODUCTSDRY EXTRACTS WITH REPRODUCIBLE CONTENT OF CHARACTERISTIC CONSTITUENTS10 STANDARDIZED, PURIFIED or OTHER CHARACTERIZED DRY EXTRACTS22 OILY / SOFT EXTRACTS WITH REPRODUCIBLE CONTENT OF CHARACTERISTIC CONSTITUENTSCHARACTERIZED.

5 STANDARDIZED OILY and SOFT EXTRACTSINGREDIENTS WITH OPTIMIZED BIOAVAILABILITY24 PHYTOSOME BOTANICAL EXTRACTS WITH ORGANOLEPTIC PROPERTIES28 FOOD & FLAVOURS67 ISOLATED or SEMISYNTHETICPURE PRODUCTSPURE MOLECULES ISOLATED OR derived FROM PLANTSBRAND - ENGLISH NAME BOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY AJMALINER auvolfia vomitoria Afz. - Root bark without rhytidoma by HPLCA ntiarrhythmic ASIATICOSIDEC entella asiatica (L.) Urban - Leaf of asiaticoside by HPLCAnti-wrinkles, Lips care BOLDINE Peumus boldus Molina - Bark of the trunk by potentiometry Choleretic CENTEROX - HETEROSIDESC entella asiatica (L.)

6 Urban - Leaf of madecassoside and terminoloside, of asiaticoside, of sum of madecassoside, terminoloside and asiaticoside by HPLC Anti-wrinkles, Collagen synthesis enhancer COLCHICINE PH. EUR. CGloriosa superba L. - Seed by potentiometryAntigout COLCHICINE USPG loriosa superba L. - Seed by HPLC Antigout COLCHICINE MICRONIZEDG loriosa superba L. - Seed by HPLCA ntigout COLCHICOSIDE Gloriosa superba L. - Seed by HPLCC hemical intermediate 10-DEACETYLBACCATIN IIIT axus baccata L. - Twig and leaf by HPLCC hemical intermediate DOCETAXELT axus baccata L.

7 - Twig and leaf by HPLCA ntimitotic / Anticancer ESCULOSIDE Aesculus hippocastanum L. - Bark of branch by HPLCV asokinetic, Capillary protectant 18 -GLYCYRRHETINIC ACID EUR. glabra Root by acidimetryAnti-inflammatory 18 -GLYCYRRHETINIC ACID Glycyrrhiza glabra Root by acidimetrySoothing, Lenitive GALANTHAMINE BROMIDRATECN arcissus pseudonarcissus L. - Bulb by HPLCA ntialzheimer PACLITAXELCT axus x media Rehder - Leaf and twig by HPLCA ntimitotic / Anticancer PACLITAXEL SCTaxus baccata L. - Leaf and twig 97% 102% by HPLCA ntimitotic / AnticancerPACKAGING MATERIALS :: Food grade polyethylene bags, multilayer bags.

8 Kraft type cardboard drums, metallic drums, polyethylene drums, polypropylene pails (UN approved drums are used for hazardous products)Indena s Active Pharmaceutical ingredients are produced in compliance with cGMPs and in pharmaceutical inspected plants, supported by s Personal Care ingredients are REACH registeredPERSONAL CAREI ndena s ingredients for food supplements are produced under Hazard Analysis and Crytical Control Points (HACCP) in authorized - FOODHALAL certifiedKOSHER certifiedCEP grantedCGGRAS: the Product can be used as an ingredient in common food (US) ECOCERT validatedECOSMOS validatedCo89 BRAND - ENGLISH NAME BOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY PRAJMALINER auvolfia vomitoria Afz.

9 - Root bark 98% 102% by potentiometryAntiarrhythmic RESERPINER auvolfia vomitoria Afz. - Root bark by potentiometryAntihypertensive RESERPINE USP Rauvolfia vomitoria Afz. - Root bark by HPLC Antihypertensive RESERPINE MICRONIZEDR auvolfia vomitoria Afz. - Root bark by potentiometryAntihypertensive SERICOSIDE Terminalia sericea Burch. ex Root bark by HPLC Antiwrinkles, Soothing, Redensifier THIOCOLCHICOSIDE (crystallized from water)Gloriosa superba L. - Seed by HPLCM uscle relaxant THIOCOLCHICOSIDE (crystallized from EtOH)Gloriosa superba L.

10 - Seed by HPLCM uscle relaxant VISNADINEAmmi visnaga (L.) Lam - Umbel without fruits by HPLCV asokinetic XIMENOIL - XIMENYNIC ACIDS antalum album L. - Seed 105% by potentiometryVasokinetic, Skin nourishingISOLATED or SEMISYNTHETICPURE PRODUCTSPURE MOLECULES ISOLATED OR derived FROM PLANTS(continue)PACKAGING MATERIALS :: Food grade polyethylene bags, multilayer bags :: Kraft type cardboard drums, metallic drums, polyethylene drums, polypropylene pails (UN approved drums are used for hazardous products)Indena s Active Pharmaceutical ingredients are produced in compliance with cGMPs and in pharmaceutical inspected plants, supported by s Personal Care ingredients are REACH registeredPERSONAL CAREI ndena s ingredients for food supplements are produced under Hazard Analysis and Crytical Control Points (HACCP) in authorized - FOODHALAL certifiedKOSHER certifiedCEP grantedCGGRAS.