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Ingenuity Pathway Analysis (IPA
Insightful data analysis and interpretation Data analysis and interpretation with IPA builds on the comprehensive, manually curated content of the Ingenuity Knowledge Base. Powerful algorithms identify regulators, relationships, mechanisms, functions, and pathways rele-vant to changes observed in an analyzed dataset. Analytics
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Ingenuity Upstream Regulator Analysis in IPA®
pages.ingenuity.com6 and the z‐score statistic is given by: V L T ê ë L Ü T Ü Ü 6 This latter formula is used in IPA to compute the activation z‐score of the transcriptional regulator. USING THE ACTIVATION Z‐SCORE TO INDEPENDENTLY CALL UPSTREAM REGULATORS Using the activation z‐score to identify upstream regulators independent of the overlap p‐value is based on the
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