1 Review Myers' Cocktail . Intravenous Nutrient Therapy: the Myers' Cocktail . Alan R. Gaby, MD. Abstract It was not clear exactly what the Myers'. Building on the work of the late John Myers, cocktail consisted of, as the information provided MD, the author has used an Intravenous by patients was incomplete and no published or vitamin-and-mineral formula for the treatment written material on the treatment was available. It of a wide range of clinical conditions. The appeared that Myers used a 10-mL syringe and modified Myers' cocktail, which consists of administered by slow IV push a combination of magnesium, calcium, B vitamins, and vitamin magnesium chloride, calcium gluconate, thiamine, C, has been found to be effective against acute vitamin B6, vitamin B12, calcium pantothenate, asthma attacks, migraines, fatigue (including vitamin B complex, vitamin C, and dilute hydro- chronic fatigue syndrome), fibromyalgia, acute chloric acid.
2 The exact doses of individual com- muscle spasm, upper respiratory tract ponents were unknown, but Myers apparently used infections, chronic sinusitis, seasonal allergic a two-percent solution of magnesium chloride, rhinitis, cardiovascular disease, and other rather than the more widely available preparations disorders. This paper presents a rationale for containing 20-percent magnesium chloride or 50- the therapeutic use of Intravenous nutrients, percent magnesium sulfate. reviews the relevant published clinical The author took over the care of Myers'. research, describes the author's clinical patients, using a modified version of his IV regi- experiences, and discusses potential side men.
3 Most notably, the magnesium dose was in- effects and precautions. creased by approximately 10-fold by using 20- (Altern Med Rev 2002;7(5):389-403) percent magnesium chloride, in order to approxi- mate the doses reported to be safe and effective Introduction for the treatment of cardiovascular , 2 In John Myers, MD, a physician from Balti- addition, the hydrochloric acid was eliminated and more, Maryland, pioneered the use of Intravenous the vitamin C was increased, particularly for prob- (IV) vitamins and minerals as part of the overall lems related to allergy or infection. Folic acid was treatment of various medical problems.
4 The au- not included, as it tends to form a precipitate when thor never met Dr. Myers, despite living in Balti- mixed with other nutrients. more, but had heard of his work, and had occa- This treatment was suggested for other sionally used IV nutrients to treat fatigue or acute patients, and it soon became apparent that the infections. modified Myers' cocktail (hereafter referred to as After Dr. Myers died in 1984, a number the Myers' ) was helpful for a wide range of clini- of his patients sought Nutrient injections from the cal conditions, often producing dramatic results. author. Some of them had been receiving injec- Over an 11-year period, approximately 15,000.
5 Tions monthly, weekly, or twice weekly for many years 25 years or more in a few cases. Chronic Alan R. Gaby, MD Past president of the American Holistic problems such as fatigue, depression, chest pain, Medical Association; author of Preventing and Reversing Osteoporosis, and co-author of The Patient's Book of or palpitations were well controlled by these treat- Natural Healing. ments; however, the problems would recur if the Correspondence address: 301 Dorwood Drive, Carlisle, PA 17013. patients went too long without an injection. Alternative Medicine Review Volume 7, Number 5 2002 Page 389. Copyright 2002 Thorne Research, Inc.
6 All Rights Reserved. No Reprint Without Written Permission Myers' Cocktail Review injections were administered in an outpatient set- Theoretical Basis for IV Nutrient ting to an estimated 800-1,000 different patients. Conditions that frequently responded included Therapy asthma attacks, acute migraines, fatigue (includ- Intravenous administration of nutrients ing chronic fatigue syndrome), fibromyalgia, acute can achieve serum concentrations not obtainable muscle spasm, upper respiratory tract infections, with oral, or even intramuscular (IM), adminis- chronic sinusitis, and seasonal allergic rhinitis. A tration.
7 For example, as the oral dose of vitamin small number of patients with congestive heart C is increased progressively, the serum concen- failure, angina, chronic urticaria, hyperthyroidism, tration of ascorbate tends to approach an upper dysmenorrhea, or other conditions were also limit, as a result of both saturation of gastrointes- treated with the Myers' and most showed marked tinal absorption and a sharp increase in renal clear- improvement. Many relatively healthy patients ance of the When the daily intake of vi- chose to receive periodic injections because it en- tamin C is increased 12-fold, from 200 mg/day to hanced their overall well being for periods of a 2,500 mg/day, the plasma concentration increases week to several months.
8 By only 25 percent, from to mg/dL. The During the past 16 years these clinical highest serum vitamin C level reported after oral results have been presented at more than 20 medi- administration of pharmacological doses of the cal conferences to several thousand physicians. vitamin is mg/dL. In contrast, IV administra- Today, many doctors (probably more than 1,000 tion of 50 g/day of vitamin C resulted in a mean in the United States) use the Myers'. Some have peak plasma level of 80 Similarly, oral made further modifications according to their own supplementation with magnesium results in little preferences. In querying audiences from the lec- or no change in serum magnesium concentrations, tern and from informal discussions with colleagues whereas IV administration can double or triple the at conferences, the author has yet to encounter a serum levels,5,6 at least for a short period of time.
9 Practitioner whose experience with this treatment Various nutrients have been shown to ex- has differed significantly from his own. ert pharmacological effects, which are in many Despite the many positive anecdotal re- cases dependent on the concentration of the nutri- ports, there is only a small amount of published ent. For example, an antiviral effect of vitamin C. research supporting the use of this treatment. There has been demonstrated at a concentration of 10- is one uncontrolled trial in which the Myers' was 15 mg/dL,4 a level achievable with IV but not oral beneficial in the treatment of musculoskeletal pain therapy.
10 At a concentration of 88 mg/dL in vitro, syndromes, including fibromyalgia. Intravenous vitamin C destroyed 72 percent of the histamine magnesium alone has been reported, mainly in present in the Lower concentrations open trials, to be effective against angina, acute were not tested, but it is possible the serum levels migraines, cluster headaches, depression, and of vitamin C attainable by giving several grams chronic pain. In recent years, double-blind trials in an IV push would produce an antihistamine ef- have shown IV magnesium can rapidly abort acute fect in vivo. Such an effect would have implica- asthma attacks.