JAID/JSC感染症治療ガイドライン2015 ―尿路感染 …

1 jaid /JSC 2015 jaid /JSC 1 2 3 4 5 6 7 8 9 10 1 2 3 4 JCHO 5 6 7 8 9 10 1 28 1 20 I .. 3II .. 41 .. 42 .. 73 ..114 ..135 ..146 ..157 ..17 III ..211 ..212.

2 22IV ..242 90 1 I ESBL Collateral damage 2012 jaid /JSC 2011 2014 jaid /JSC 2014

3 1 A B C I II III IV 2 3 jaid /JSC 2015 3 28 1 20 II 1 Executive summary Staphylococcus saprophyticus Escherichia coli BLI -lactamase inhibitor 90 BLI BII E.

4 Coli BLI BII ESBL FRPM FOM BII AII 2 3 CIV 1 2 3 BIV CIV 3 4 AII E.

5 Coli 70 Proteus mirabilis Klebsiella 80 85 15 20 Staphylococcus Streptococcus Enterococcus 5 6 E. coli BLI ST 10 5 6 E. coli 5 ESBL 70 FOM FRPM 6 jaid /JSC 2011 E. coli ESBL 7 3 S.

6 Saprophyticus 17 E. coli BLI 90 6 4 90 1 jaid /JSC 2015 BLI BII 9 E. coli 18 BLI BII ST 3 BLI 7 7 3 3 8 9 I 1 1 5 7 10 BIV 80 90 E.

7 Coli P. mirabilis Klebsiella 20 S. saprophyticus Staphylococcus Streptococcus Enterococcus 5 6 E. coli BLI BLI 90 5 6 BII 3 4 BII BLI BII ESBL 70 FOM FRPM TAZ/PIPC ESBL LVFX 1 500mg 1 1 3 CPFX 1 200mg 1 2 3 3 TFLX 1 150mg 1 2 3 CCL 1 250mg 1 3 7 CVA/AMPC 1 125mg/250mg 1 3

8 7 CFDN 1 100mg 1 3 5 7 CFPN-PI 1 100mg 1 3 5 7 CPDX-PR 1 100mg 1 2 5 7 FOM 1 1g 1 3 2 FRPM 1 200mg 1 3 7 ESBL 1 2 11 I 3 CPFX 3 1 12 AI 5 28 1 20 jaid /JSC 2015 E. coli E. coli BLI BII ESBL FRPM FOM BIV 50 65 1 1 13 BII CCL 1 250mg 1 3 7 CVA/AMPC 1 125mg/250mg 1 3 7 CFDN 1 100mg 1 3 5 7 CFPN-PI 1 100mg 1 3 5 7 CPDX-PR 1 100mg 1 2 5 7

9 LVFX 1 500mg 1 1 3 CPFX 1 200mg 1 2 3 3 TFLX 1 150mg 1 2 3 FOM 1 1g 1 3 2 FRPM 1 200mg 1 3 7 ESBL 1 3 CIV 1 1 5 7 ST 13 BII CVA/AMPC FOM BIV 14 BII CFDN 1 100mg 1 3 5 7 CFPN-PI 1 100mg 1 3 5 7 CPDX-PR 1 100mg 1 2 5 7 CCL 1 250mg 1 3 7 CVA/AMPC 1 125mg/250mg 1 3 7 FOM 1 1g 1 3 2 3 6 90 1 jaid /JSC 2015 1 4

10 E. coli Klebsiella Citrobacter Enterobacter Serratia Proteus Pseudomonas aeruginosa Enterococcus Staphylococcus ESBL MRSA 8 9 BII BIV de-escalation BIV BIV LVFX 1 500mg 1 1 7 14 CPFX 1 200mg 1 2 3 7 14 TFLX 1 150mg 1 2 7 14