Transcription of JAID/JSC感染症治療ガイドライン2016 ―歯性感染症―
1 JAID/JSC 2016 JAID/JSC 1 1 2 3 4 5 1 2 3 4 5 VOL. 64 NO. 4641I JAID/JSC 2011 JAID/JSC 2011 2014 JAID/JSC 2014 JAID/JSC 2014 Prevotella - - - JAID/JSC 2014 1 A B C I II III IV 2
2 3 4 J U L Y 2 0 1 6642II 1 2 - 1 4 1 1 2 3 1 2 1 2 4 1 3 2005 2009 3,112 Streptococcus 73 Prevotella 48 Peptostreptococcus 47 Prevotella P.
3 Intermedia Peptostreptococcus Peptostreptococcus Parvimonas Finegoldia Peptoniphilus P. micros Parvimonas micra Fusobacterium Porphyromonas 9 6 2 Streptococcus S. constellatus S. intermedius S. mitis S. oralis 1 4 4 2 Streptococcus anginosus group S. anginosus, S. intermedius S. constellatus Streptococcus 2 2008 2009 MIC Prevotella - ABPC ampicillin CFDN cefdinir CTRX ceftriaxone MIC90 16 g/mL - SBT/ABPC sulbactam/ampicillin MIC90 2 g/mL AZM azithromycin CLDM clindamy-cin MIC90 16 g/mL CLDM MIC50 g/mL MNZ metronidazole MIC90 4 g/mL Porphyromonas - MIC90 g/mL Fusobacterium AZM MIC90 MIC90 3 Peptostreptococcus Streptococcus anginosus group - MIC90 Viridans streptococci AZM CLDM MIC50 MIC90 3 STFX sitafloxacin MIC90 g/mL 8 256 4
4 VOL. 64 NO. 4643 Prevotella - - A D A B C D Prevotella A 2e - 3 sulbactam tazobactam - Prevotella 681 - 240 35 CLSI ABPC 37 CTRX 13 CLDM 10 5 3 8 6 1 1 2 AMPC amoxicillin 1 250mg 1 3 4 1 10 15mg/kg 1 3 A IV1 CLDM clindamycin 1 150mg 6 B I7 8 AZM 1 500mg 1 1 3 B I9 10 AZM 1 2g 1 1 CAM clarithromycin 1 200mg 1 2 1 1 2 * B II11
5 3 4 - SBTPC sultamicillin * 1 375mg 1 2 3 C SBTPC CVA/AMPC clavulanic acid/amoxicillin 1 250mg 1 4 C AMPC 1 500mg 1 3 1 15mg/kg 1 3 C CLDM 1 150mg 6 C I12 CCL cefaclor 1 250mg 1 3 1 15mg/kg 1 3 B 15 STFX sitafloxacin 1 100mg 1 2 C III4 2 - STFX 1 100mg 1 2 C III4 FRPM faropenem 1 150 200mg 1 3 1 5mg/kg 1 3 C 3 3 4 Needle aspiration CT J U L Y 2 0 1 6644 SBT/ABPC sulbactam/ampicillin 1 3g 2 4 1 75mg/kg 1 3 C SBT/ABPC CTRX 1 1 2g 1 1 2 1 25 60mg/kg 1 1 2 50 60mg/kg/ B MEPM meropenem 1 1g 1 3 30 1 20mg/kg 1 3 1 120mg/kg C III13 DRPM doripenem 1 1g 1 3 30 1 20mg/kg 1 3 1 40mg/kg 1 1g C III14 CLDM C CLDM 4 2008 AHA American Heart Association 15 2009 16 6 2008 17 NICE National Institute for Health and
6 Clinical Excellence 18 1 AMPC 2g 1 30mg/kg A IV15 16 18 CLDM 600mg 2g B IV18 AZM 500mg B IV18 CAM clarithromycin 500mg B IV18 CEX cefalexin CDX cefadroxil 2g B IV18 19 19 AMPC50 mg/kg 1 ABPC50 mg/kg 30 CLDM20 mg/kg 1 CEX50 mg/kg 1 AZM15 mg/kg 1 CAM15 mg/kg 1 CLDM20 mg/kg 30 CEZ50 mg/kg 30 VOL. 64 NO. 4645 MSD III 1 2005 2011-2014 2010 2010 56 546 524 sitafloxacin 2008 56 S-1 121 Prevotella -lactamase 60 2012 Research, Science and Therapy Committee of the American Academy of Periodontology.
7 Position Paper. Systemic Antibiotics in Periodontics. J Periodontal 2004 75 1553 Mangundjaja S, Hardjawinata K Clindamycin versus ampicillin in the treatment of odontogenic infections. Clin Ther 1990 12 242 Cachovan G, Boger RH, Giersdorf I, Hallier O, StreichertT, Haddad M et al Comparative efficacy and safety of moxifloxacin and clindamycin in the treatment of odontogenic abscesses and inflammatory infiltrates a phase II, double-blind, randomized trial. Antimicrob Agents Chemother 2011 55 1142 7. 9 Sasaki J, Kaneko A, Karakida K, Shiiki K, Sakamoto H, Naitoh H et al Comparative clinical study of azithro-mycin with tosufloxacin tosilate in the treatment of acute odontogenic infection. Jpn J Antibiot 1995 48 1093 Adriaenssen CF Comparison of the efficacy, safety and tolerability of azithromycin and co-amoxiclav in the treatment of acute periapical abscesses. J Int Med Res 1998 26 257 TE-031 Chemotherapy 1988 36 S-3 1058 Rush DE, Abdel-Haq N, Zhu JF, Aamar B, Malian M.
8 Clindamycin versus Unasyn in the treatment of facial cellulitis of odontogenic origin in children. Clin Pediatr Phila 2007 46 2 154 Meropenem Chemotherapy 1992 40 S-1 732 doripenem 2005 53 S-1 323 Nishimura RA, Carabello BA, Faxon DP, Freed MD, Lytle BW, O Gara PT et al. ACC/AHA 2008 Guideline Update on Valvular Heart Disease Focused Update on Infective Endocarditis. J AM Coll Cardial 2008 52 8 676 Gilbert H, Bruno H, Pilar T, Franck T, Bernard P, Isidre V et al, Guidelines on the prevention, diagnosis and treatment of infective endocarditis new version 2009 . European Heart Journal 2009 30 2369 National Institute for Health and Clinical Excellence Prophylaxis against infective 2008 2008 JAID/JSC IV JAID/JSC 2014 2014 J U L Y 2 0 1 6646
