Transcription of JCOG1019 - トップページ：日本臨床腫瘍研究 ...
1 Japan Clinical Oncology Group H22- - -026 26-A-4 JCOG1019 High grade T1 second TUR T0 BCG III Phase III clinical trial in determining treatment strategy for patients with High grade T1 bladder cancer who have pT0 histology on the second TUR BC pT0 phase III 761-0793 1750-1 930-0194 2630 2008 9 6 JCOG PC804 2011 7 27 JCOG 2013 2 20 JCOG 2 22 2013 7 30 JCOG 8 5 2014 3 7 JCOG 3 18 2016 6 10 JCOG 6 13 JCOG 10 19 ver 2/78 0.
2 turbt High grade T1 2nd TUR T0 BCG BCG A B Tis Ta Primary endpoint Tis Ta Secondary endpoints T2 ) / turbt CIS CIS High grade T1 JCOG 10 19 ver 3/78 turbt turbt turbt turbt 2) 20 85 3)
3 / turbt 56 turbt day 0 day 56 1 turbt turbt 56 2 turbt T1 T0 turbt 56 4) Performance Status PS ECOG 0 1 PS 5) 6) 7) BCG 8) Tis Ta 9) 14 2 3,000/mm3 g/dL 100,000/mm3 mg/dL mg/dL AST GOT 100 IU/L ALT GPT 100 IU/L 10) 11) ) 2nd TUR T0 1 2 2nd TUR 2) turbt 2 2 Papanicolau 5 class V V 3) 2nd TUR 28 2nd TUR day 0 day 28 4) 14 2 3,000/mm3 12,000/mm3 100,000mm3 5)
4 CT MRI JCOG 10 19 ver 4/78 High grade T1 2nd TUR T0 1 BCG A 2 B 3 T0 T0 C A BCG 80 mg 81 mg 1 1 1 8 B C 575 130 260 7 5 3 12 CRF JCOG JCOG
