Transcription of エビデンスに基づく - jsn.or.jp
1 2020 RPGN 2020 RPGN RPGN 2020 3,000 ISBN978-4-88563-723-0C3047 3000E 1 RPGN CKD RPGNGL WG SR
2 IgA RPGN ii RPGN 2020iii 29 31 IgA 4 20 22 23 23 25 4 2014 26 28 2017 6 29 4 14 4 QOL 2020 8 iv RPGN 2020 CONTENTS vi 11 RPGN 12 RPGN 23 24 ANCA 35 GBM 56 RPGN CKD 6 71 72
3 93 ANCA 114 GBM 175 206 RPGN 237 RPGN 248 RPGN 30 311 312 331 ANCA GBM 351 ANCA 352 GBM 481 482 483 524 545 543 56 I 1 II 7 III 31 IV 35 v RPGN 2020 CONTENTS1 562 573 574 585 592 CQ 601 ANCA RPGN 602 CQ 61CQ 1 ANCA RPGN 61 61CQ 2 ANCA RPGN 63 63CQ 3 ANCA RPGN 66 66CQ 4 ANCA RPGN 68 68 70 70 73 V 70 vi1 RPGN rapidly progressive glomerulonephritis 2017 2002 2011 2 RPGN WG 2014 RPGN 2014 20 CQ CQ 2017 2012 KDIGO Kidney Disease Improving Global Outcomes RPGN pauci immune focal and segmental necrotizing glomerulonephritis anti GBM anti-body glomerulonephritis lupus nephritis ANCA BSR BHPR 2014 EULAR ERA EDTA 2016
4 2011 ANCA 2014 2017 2019 MPA GPA 2 2017 CQ RPGN CQ CQ Minds CQ RPGN 2020 WG vii RPGN CQ CQ 20 4 CQ 5 RPGN 3 ANCA GBM IgA 2017 2014 ANCA RPGN GBM RPGN 3 SLE ANCA RPGN GBM RPGN 2 RPGN 4 2017 4 Minds GRADE CQ RCT working group WG CKD 2018 RPGN 4 13 CQ SR 2 15
5 5 CQ 2 CQ WG SR CQ 1 SR 4 CQ 1 2 CQ 2018 9 SR CQ SR 2019 9 WG 1 2 20 CQ WG RPGN 2019 12 SR 5 4 CQ viii RPGN 2020 RPGN ANCA GBM 2 GRADE ANCA ANCA RPGN Chapel Hill 2012 2016 6 I II III IV V I IV IV 4 CQ CQ CQ SR 7
6 WG 2 Minds 2017 2 4 A B C D 8 RPGN RPGN RPGN 9 29 ix RPGN 2020 10 RPGN ANCA 1 RPGN WHO 1 eGFR 3 30
7 RPGN RPGN rapidly progressive glomerulonephritis WHO RPGN pauci immune 3 glomerular basement membrane GBM SLE IgA Henoch Sch nlein circulating immune complex in situ GBM 2012 Chapel Hill Consensus Conference CHCC in situ anti neutrophil cytoplasmic antibody ANCA ANCA ANCA myeloperoxidase MPO MPO ANCA proteinase 3 PR3 PR3 ANCA 10 1 RPGN I2 RPGN 2020 I RPGN 1 2 RPGN RPGN RPGN RPGN RPGN 2 RPGN ANCA glomerular basement mem-brane GBM IgA 1 RPGN systematic lupus erythematosus SLE hemolytic uremic syndrome HUS thrombotic microangiopathy TMA RPGN 2 50 RPGN
8 Tubulointerstitial nephritis TIN RPGN pauci immune 3 3 1 3 pauci immune 1,4 ANCA ANCA ANCA 2 RPGN 3 1 RPGN I II 1 GBM Pauci immune 2 IgA IgA 3 1 MPA GPA Wegener EGPA Churg Strauss GBM Goodpasture SLE IgA Henoch Sch nlein hemolytic uremic syndrome HUS 2 MRSA C 3 ANCA 3 RPGN 2020 I I ANCA associated vasculitis AAV GBM GBM in situ immune complex formation
9 SLE IgA circulating immune complex IgA IgA 1 ANCA ANCA 5 renal limited AAV ANCA perinuclear pattern P ANCA cytoplasmic pattern C 4 ANCA 2 1998 A 1999 2001 B 2002 C
