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〔日常臨床で遭遇したら〕 - jsog.or.jp

N 143.. 1 .. 2 .. 3 .. 4 .. 16 n=39 . 15 n=76 .. 14. 13. 12 *. 11. *. 10. 9 *. 8. *p<.05. *. 7.. 1 2 3 4 5 6 7 8 9 1011 12131415161718192021. -glucuronidase .. 1 .. Kivlahan and James, 1984 1 . 1 .. 2 6 8mg . kg . 1 24 . 2 1 5mg/dl .. 3 12mg/dl . 15mg/dl . bilirubin-UDP-glucuronyl 4 2mg/dl . transferase . 5 2 .. -glucuronidase .. 2 3 . 4 . 5 12mg dl 7 1 1 . 2 .. N 144 .. 1 .. ABO . RhD . glucose-6-phosphate deficiency G6PD . 3 .. - thalassemia . 24 . 2 . ABO . O . A B . O IgG A . B Crigler-Najjar . Lucey-Driscoll . ABO . RhD . 3 . Rh . ABO .. glucose-6-phosphate deficiency G6PD . RhD .. 7 10 48.

(表4) 核黄疸の臨床症状(Van Praagh, 1961)2 ) 第1期 モロー反射減弱,筋緊張低下,嗜眠傾 向,哺乳不良 第2期 後弓反張,痙攣,発熱,硬直,甲高い

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Transcription of 〔日常臨床で遭遇したら〕 - jsog.or.jp

1 N 143.. 1 .. 2 .. 3 .. 4 .. 16 n=39 . 15 n=76 .. 14. 13. 12 *. 11. *. 10. 9 *. 8. *p<.05. *. 7.. 1 2 3 4 5 6 7 8 9 1011 12131415161718192021. -glucuronidase .. 1 .. Kivlahan and James, 1984 1 . 1 .. 2 6 8mg . kg . 1 24 . 2 1 5mg/dl .. 3 12mg/dl . 15mg/dl . bilirubin-UDP-glucuronyl 4 2mg/dl . transferase . 5 2 .. -glucuronidase .. 2 3 . 4 . 5 12mg dl 7 1 1 . 2 .. N 144 .. 1 .. ABO . RhD . glucose-6-phosphate deficiency G6PD . 3 .. - thalassemia . 24 . 2 . ABO . O . A B . O IgG A . B Crigler-Najjar . Lucey-Driscoll . ABO . RhD . 3 . Rh . ABO .. glucose-6-phosphate deficiency G6PD . RhD .. 7 10 48.

2 Pregnandiol . -glucuronidase .. 4 2 .. 25mg dl ABO RhD . G6PD .. 20mg dl 5 . N 145.. Van Praagh, .. 1961 2 ).. 10mg dl .. IgM.. SFD .. RhD ABO .. G6PD .. Crigler-Najjar .. 2 1997 3 . N 146 .. 6). mg/dl . 1993 . 24 48 72 96 120 5 .. / / / / / / . 1,000g 5/8 6/10 6/12 8/12 8/15 10/15. 1,500g 6/10 8/12 8/15 10/15 10/18 12/18. 2,500g 8/10 10/15 12/18 15/20 15/20 15/20. 2,500g 10/12 12/18 15/20 18/22 18/25 18/25.. 2 3 . IgM.. 24 . 2 .. 1958 Cremer et .. 5 .. 6 6 . 5 . 7 .. van Praagh .. 1 Kivlahan C, James EJP. The natural history of neonatal jaundice. Pediatrics 1984 ; 74 : 364 370. 2 Van Praagh R.

3 Diagnosis of kernicterus in the neonatal period. Pediatrics 1961 ; 28 : 870 876. 3 . 1997 ; 428 435. 4 Cremer RJ, et of light on the hyperbilirubinemia of infants. Lan- cet 1958 ; 1 : 1094 1097. 5 1985 ; 43 : 1557 1565. 6 1993 : 205 224. 7 1981 ; 11 : 2059 2061.


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