核医学研究会 （核医学夢工房 ... - jsrt-chushi.jp

1 14 25 7 7 10:00 15:00 301 SPECT - SPECT - PET 10:00 11:45 10:00 10:45 SPECT - - 10:55 11:45 SPECT 13:00 15:00 13:00 13:50 SPECT - SPECT - 14:00 15:00 PET SPECT Ordered subset expectation maximization(OSEM) single photon emission computed tomography(SPECT) SPECT 3 NEMA 37mm SPECT 17mm FWHM aspect ratio.

2 ASR Recovery Coefficient RC) Coefficient Variation %CV SPECT/CT SymbiaT16 SIEMENS BrightViewX with XCT Infinia Hawkeye4 99mTcO4- SPECT 25 30 35cm 128 128 1 3 360 2 Filtered Back Projection(FBP) OSEM OSEM Flash3D Astonish Evolution Subset 10 Iteration 1 30 dual Energy windows:DEW CT OSEM Iteration OSEM Iteration 17mm 22mm 37mm 37mm OSEM OSEM 35cm 28 22mm OSEM 17mm Iteration OSEM OSEM FWHM FBP OSEM 17mm ASR Iteration Subset Iteration 30 100 %CV OSEM SI SI OSEM SPECT

3 Iteration (IQ SPECT) IQ SPECT IQ SPECT 55cm 28cm 225cm sweet spot sweet spot OSCGM CTAC TEW LEHR L Tc Tc SPECT sweet spot upward creep

4 IQ SPECT SPECT SPECT 24 4 GE SPECT SPECT Infinia3 CZT SPECT Discovery NM 530c D530c D530c SPECT Infinia3 CZT 1957 SPECT X-CT CZT Cd Zn Te 18 27 C GE 1 [mm] Infinia3 1 2 3 4 10 1 D530c CZT 3D 3-D iterative Bayesian reconstruction algorithm SPECT AlcyoneTechnology D530c Lister Xeleris R R Infinia3 D530c SPECT NEMA GE SPECT 16 12 8 [cm] SPECT 99mTc 296[MBq/ml]

5 16 [cm] JSP [cm] 3 L FWHM full width at half-maximum Infinia3 D530c D530c 99mTc 123 2 Infinia3 D530c Infinia3 SPECT 99mTc 123 SPECT SPECT D530c RI 4[MBq/kg] 3[MBq/kg] [MBq/kg] 3 CZT SPECT SPECT PET PET PET NEMA Standards Publication NU2-2007 Performance Measurements of Positron Emission Tomographs JESRA X-0073*C-2008 PET JESRA TI-0001*C-2009 PET FDG PET FDG 20 PET FDG -PET/CT 2009 4.

6 1 10mm PET Version Up NEMA NU2-2007 QC/QA noise equivalent count;NECphantom 10mm % % FDG- PET/CT PET (True;T) (Scatter;S) (Random;R) 3 PET noise equivalent count;NEC PET NEC=T2/T+S+(1+k)fR[Mcounts] f k (2D 3D) NECphantom Tortal Prompt= True+Scatter+Random Delayed Prompt=Random SF.

7 NEC=(1-SF)2(T+S)2/(T+S)+(1+k)fR [Mcounts] (10,13,17,22,28,37mm) 4:1 30 RCj=Cj/C37mm Cj: C37mm:37mm GE Discovery Ls NECphantom > N10mm < QH,10mm/N10mm > Relative RC10mm > Discovery Ls NECphantom > 3D 3 2D 6 3D 4 2D 10 N10mm< QH,10mm/N10mm > NECphantom 2D 1 5 FWHM10mm 5 2D 2D NECphantom 10mm % % PET PET FDG- PET/CT PETquact PET