Transcription of アルコール依存症への 理解 ... - kanen.ncgm.go.jp
1 1 .. 1. 0 0-9 10-19 20-29 30-39 40-49 50-59 60- (g).. 1 60 .. 60 : 3 . 350mL 3 . 3 . 25 300mL .. 20 . 1 1 .. 10 .. 65 .. (ICD-10) (ICD-10, DSM-IV). (DSM-IV). (DSM-5). (Harmful use). (ICD-10).. (ICD-10). 1 3 .. 1 .. (DSM-5). 1 2 (2-3: 4-5: 6-: . 1) . 2) . 3) . 4) . 5) . 6) . 7) .. 8) . 9) .. 10) a . b . 11) a . b .. ICD-10 . 197 . 21 . ICD-10 . %. %. 72 8 80 .. 2005.. , . , . , , .. %.. 50 .. 40 . 30 .. 20 . Tomas VS et al., JAGS. 2001. 10. 0.. MMSE .. % .. 80 . MMSE . 70 1 1 . 60 . 50 2 2 .. 40. 2 . 30. 1 10% . 20 . 10 10% . 0 . 50 60 70 10% . (N = 16) (N = 61) (N = 36).
2 19 .. 22.. ( ).. (Harm Reduction Approach).. Feedback Advise Goal- setting . HAPPY .. AUDIT.. KAST.. CAGE.. GTP .. ALDH .. NMDA .. CO2. H2O.. ALDH2 . MEOS .. Fuller&Roth, 128/NA 52 NA. 1979. Fuller et al., 605/577 52 NA. 1986. Shuckit, 348/348 52 NA . 1985. Chick et al., 126/69 24 NA . 1992. (Garbutt et al., JAMA, 1998 ).. NMDA . GABA-A . 1989 2004 .. 2013 5 .. AA.. 1935 . 1975 . AA .. Alcoholics Anonymous: The Big Book, 1973.. AA 1957 1958 .. 1963 . 1970.
