Laboratory water purification systems - ADRONA

1 Laboratory water purification systems2 Choosing a water purification systemApplicationISO 3696 classificationSuggested model and configurationPageFeed water for labware washersGrade 3 Sterifeed20 Feed water for autoclavesCrystal 7 RO18 Glassware rinsingCrystal E RO15 Feed water for automated biochemistry analyzersGrade 2 Crystal Clinic22 General Laboratory workGrade 2 Crystal 7 Pure18 ElectrochemistryFlame AASC rystal E Pure15 Wet chemistrySpectrophotometryCrystal B Pure10 Buffer and media preparationReagent preparationGrade 1 Crystal E Trace12 Ion chromatographyICP-MSCrystal B Trace3 Graphite AASICP-OESHPLCG rade 1 Crystal E HPLC12 Crystal B HPLC3 Gas chromatographyIntegrity HPLC6 TOC measurementsOnsite HPLC8 Flow cytometryGrade 1 Crystal E Bio12 Crystal B Bio3 Cell and tissue cultureIntegrity Bio6 Molecular biologyOnsite Bio83 ultrapure water systemsCrystal B ultrapure systems are multi-purpose water purification systems .

2 The Crystal B systems produce ultrapure and pure water directly from tap B ultrapure systems are available in the following configurations:Crystal B Trace (P/N CB-1015) produces water for inorganic trace analysis. water can be used for atomic absorption spectrometry (with graphite furnace atomizer), ICP-OES ana-lysis, ICP-MS and other inorganic analytical B HPLC (P/N CB-1101) produces water with very low or-ganic carbon (TOC) content mee-ting requirements of liquid chro-matography methods. Crystal B HPLC water can also be used for some microbiological and molecular biology appli B Bio (P/N CB-1201) system produces water with very low organic and RNase/DNase content that is intended for the use in molecular biology, including RNase-sensitive configuration of a Crystal B ultrapure system produces both ultrapure and pure water .

3 ultrapure (Grade 1) water is dispensed through the point-of-use filter on the front panel. Pure (Grade 2) water is dispensed directly from the storage tank. Crystal B ultrapure water can be used for the most demanding appli cations including, but not li-mited to: inorganic trace analysis liquid chromatography cell culture molecular biologyWith resistivity of Mega-Ohm*cm ( S/cm) ultrapure water produced by a Crystal B system exceeds requirements of all relevant standards (ISO 3696 Grade 1, ASTM Type I, CLSI Type I).

4 Purified water is collected in a storage tank. An integrated recirculation system ensures consistent quality of water and reduces total organic carbon (TOC) to very low levels: <2ppb for HPLC and Bio configurations and 5-10 ppb for the Trace configuration. Pure water produced by the Crystal B systems complies with the requirements of ISO 3696 Grade 2 water and can be used for labware washing, wet chemistry methods, flame spectrophotometers, etc. The dispense rate of ultrapure water is 2 L/min. Whereas the dispense rate of pure water is 4 Crystal B systems have a controller with a graphic LCD display for water quality indi-cation.

5 The LCD display provides all necessary information about sys-tem status, as well as the remaining pre-filter life and deionization (DI) module performance. The smart DI module monitoring system also provides a reduction in running costs. A user is instructed to replace the DI module only when the module is near the end of its service life. If a Bluetooth option (P/N 10103) is installed, the controller can be de-tached, so the Crystal B system can be controlled remotely. If space-saving is crucial, wall-mounting the Crystal B, and the use of a re-mote control is the right choice.

6 All cartridges and filters are easily ac-cessible and no tools are required to replace them. The Crystal B sys-tem can be installed on a labora-tory bench or mounted on a Crystal B has important safety functions:tank filling control tap water pressure control protection from tank sensor failure The Crystal B systems include:Boost pump Pre-filter set Reverse osmosis module Deionization module Final stage polishing module 25L storage tank with an inte- grated Grade II dispensing pumpRecirculation system Point-of-use final filter ( m microfilter for the Crystal B Trace and HPLC systems )Ultrafilter for the Crystal B Bio systems .

7 And/or a photo-oxida-tion module for elimination of organics (HPLC and Bio configu-rations)UV sterilization module (Bio configuration)Crystal B series4 InputvalveActivatedcarbon/5umpre-filterB oostpumpDrainPressureswitchInputStrainer Reverseosmosismodule(RO module)CheckvalveFlowrestrictorPure waterqualitysensorPure waterdispenseStoragetankPure (Grade 2) water dispense pumpDeionizationmoduleRecirculationpumpS huntingrestrictorRecirculationvalvePolis hingmoduleProtectivefilterUltrapurewater qualitysensorUltrapure waterdispense valveUltrapure waterdispenseFinal pointof-use filterInputvalveActivatedcarbon/5umpre-f ilterBoostpumpDrainPressureswitchInputSt rainerReverseosmosismodule(RO module)CheckvalveFlowrestrictorDual wavelengthUV photooxidationmodule (185/254 nm)Pure waterqualitysensorPure waterdispenseStoragetankPure (Grade 2)

8 water dispense pumpDeionizationmoduleRecirculationpumpS huntingrestrictorRecirculationvalvePolis hingmoduleProtectivefilterUltrapurewater qualitysensorUltrapure waterdispense valveUltrapure waterdispenseFinal pointof-use filterUV sterilization module (254 nm)InputvalveActivatedcarbon/5umpre-filt erBoostpumpDrainPressureswitchInputStrai nerReverseosmosismodule(RO module)CheckvalveFlowrestrictorDual wavelength UV photooxidation module (185/254 nm)Pure waterqualitysensorPure waterdispenseStoragetankPure (Grade 2) water dispense pumpDeionizationmoduleRecirculationpumpS huntingrestrictorRecirculationvalvePolis hingmoduleProtectivefilterUltrapurewater qualitysensorUltrapure waterdispense valveUltrapure waterdispenseFinal pointof-use filter Crystal B Trace Crystal B HPLC Crystal B BioFlow diagramsSpecificationsPurified water specificationsCrystal B TraceCrystal B HPLCC rystal B BioPure (Grade 2) water resistivity>10 M x cm>10 M x cm>10 M x cmPure (Grade 2) water conductivity< S/cm< S/cm< S/cmUltrapure (Grade 1) water M x M x M x cmUltrapure (Grade 1)

9 water S/cmTOC5 10 ppb<2 ppb<2 ppbRNase < ng/mLDNase <4 pg/ LBacteria< 1 cfu/mL< 1 cfu/mL< 1 cfu/mLEndotoxins< EU/mL< EU/mL< EU/mLParticles > m<1/ per mL<1/ per mL<1/ per mLNominal flow, pure water (to storage tank)10 L/h10 L/h10 L/hNominal dispense flow, ultrapure water2 L/min2 L/min2 L/minNominal dispense flow, pure water4 L/min4 L/min4 L/minDeionization module life (standard module)1 m31 m31 m3 Recovery>30 %>30 %>30 %Dimensions (WxDxH), cm50x40x6050x40x6050x40x60 Storage tank25 L25 L25 LTank dimensions (WxDxH), cm30x25x5030x25x5030x25x50 Feed water 5 5 5 barFeed water conductivity< 900 S/cm< 900 S/cm< 900 S/cmApplicationsApplicationCrystal B TraceCrystal BHPLCC rystal BBioReagent preparation Ion chromatography ICP-MS Atomic absorption spectrophotometry with graphite atomizer ICP-OES HPLC Gas chromatography Total Organic Carbon measurement Flow cytometry Cell and tissue culture Molecular biology 5 ConsumablesPart numberDescriptionReplacement criteriaComments10019 Replacement pre-filter set.

10 Crystal BFilter life counter is zero or the filter is clogged 10310 Replacement deionization module DI Err message is shown, or water conductivity is consistently > S/cm 10029 Replacement polishing moduleEvery 1 2 years, depending on operation 10011 Replacement sterilization UV bulbAs required (on average every 3 years) Bio systems only10018 Replacement photooxidation UV bulbAs required (on average every 3 years) HPLC and Bio systems10012 Replacement m dispense microfilterEvery 6 12 months Trace and HPLC systems10120 Replacement ultrafilterEvery 6 12 months Bio systems onlyComponentsPart numberAccessoryCrystal B TraceCrystal B HPLCC rystal B Bio10019 Pre-filter set for chlorine and organics reduction+++Boost pump+++Reverse osmosis module+++10310 Deionization module.