Laboratory water purification systems - ADRONA

1 Laboratory water purification systems2 Choosing a water purification systemApplicationISO 3696 classificationSuggested model and configurationPageFeed water for labware washersGrade 3 Sterifeed20 Feed water for autoclavesCrystal 7 RO18 Glassware rinsingCrystal E RO15 Feed water for automated biochemistry analyzersGrade 2 crystal Clinic22 General Laboratory workGrade 2 crystal 7 Pure18 ElectrochemistryFlame AASC rystal E Pure15 Wet chemistrySpectrophotometryCrystal B Pure10 Buffer and media preparationReagent preparationGrade 1 crystal E Trace12 Ion chromatographyICP-MSCrystal B Trace3 Graphite AASICP-OESHPLCG rade 1 crystal E HPLC12 crystal B HPLC3 Gas chromatographyIntegrity HPLC6 TOC measurementsOnsite HPLC8 Flow cytometryGrade 1 crystal E Bio12 crystal B Bio3 Cell and tissue cultureIntegrity Bio6 Molecular biologyOnsite Bio83 UltrapUre water systemsCrystal B ultrapure systems are multi-purpose water purification systems . The crystal B systems produce ultrapure and pure water directly from tap B Ultrapure systems are available in the following configurations: crystal B Trace (P/N CB-1015) produces water for inorganic trace analysis.

2 water can be used for atomic absorption spectrometry (with graphite furnace atomizer), ICP-OES ana-lysis, ICP-MS and other inorganic analytical B HPLC (P/N CB-1101) produces water with very low or-ganic carbon (TOC) content mee-ting requirements of liquid chro-matography methods. crystal B HPLC water can also be used for some microbiological and molecular biology appli B Bio (P/N CB-1201) system produces water with very low organic and RNase/DNase content that is intended for the use in molecular biology, including RNase-sensitive configuration of a crystal B ultrapure system produces both ultrapure and pure water . Ultrapure (Grade 1) water is dispensed through the point-of-use filter on the front panel. Pure (Grade 2) water is dispensed directly from the storage tank. crystal B ultrapure water can be used for the most demanding appli cations including, but not li-mited to: inorganic trace analysis liquid chromatography cell culture molecular biologyWith resistivity of Mega-Ohm*cm ( S/cm) ultrapure water produced by a crystal B system exceeds requirements of all relevant standards (ISO 3696 Grade 1, ASTM Type I, CLSI Type I).

3 Purified water is collected in a storage tank. An integrated recirculation system ensures consistent quality of water and reduces total organic carbon (TOC) to very low levels: <2ppb for HPLC and Bio configurations and 5-10 ppb for the Trace configuration. Pure water produced by the crystal B systems complies with the requirements of ISO 3696 Grade 2 water and can be used for labware washing, wet chemistry methods, flame spectrophotometers, etc. The dispense rate of ultrapure water is 2 L/min. Whereas the dispense rate of pure water is 4 crystal B systems have a controller with a graphic LCD display for water quality indi-cation. The LCD display provides all necessary information about sys-tem status, as well as the remaining pre-filter life and deionization (DI) module performance. The smart DI module monitoring system also provides a reduction in running costs.

4 A user is instructed to replace the DI module only when the module is near the end of its service life. If a Bluetooth option (P/N 10103) is installed, the controller can be de-tached, so the crystal B system can be controlled remotely. If space-saving is crucial, wall-mounting the crystal B, and the use of a re-mote control is the right choice. All cartridges and filters are easily ac-cessible and no tools are required to replace them. The crystal B sys-tem can be installed on a labora-tory bench or mounted on a crystal B has important safety functions:tank filling control tap water pressure control protection from tank sensor failure The crystal B systems include:Boost pump Pre-filter set Reverse osmosis module Deionization module Final stage polishing module 25L storage tank with an inte- grated Grade II dispensing pumpRecirculation system Point-of-use final filter ( m microfilter for the crystal B Trace and HPLC systems )Ultrafilter for the crystal B Bio systems .

5 And/or a photo-oxida-tion module for elimination of organics (HPLC and Bio configu-rations)UV sterilization module (Bio configuration) crystal B series4 InputvalveActivatedcarbon/5umpre-filterB oostpumpDrainPressureswitchInputStrainer Reverseosmosismodule(RO module)CheckvalveFlowrestrictorPure waterqualitysensorPure waterdispenseStoragetankPure (Grade 2) water dispense pumpDeionizationmoduleRecirculationpumpS huntingrestrictorRecirculationvalvePolis hingmoduleProtectivefilterUltrapurewater qualitysensorUltrapure waterdispense valveUltrapure waterdispenseFinal pointof-use filterInputvalveActivatedcarbon/5umpre-f ilterBoostpumpDrainPressureswitchInputSt rainerReverseosmosismodule(RO module)CheckvalveFlowrestrictorDual wavelengthUV photooxidationmodule (185/254 nm)Pure waterqualitysensorPure waterdispenseStoragetankPure (Grade 2) water dispense pumpDeionizationmoduleRecirculationpumpS huntingrestrictorRecirculationvalvePolis hingmoduleProtectivefilterUltrapurewater qualitysensorUltrapure waterdispense valveUltrapure waterdispenseFinal pointof-use filterUV sterilization module (254 nm)InputvalveActivatedcarbon/5umpre-filt erBoostpumpDrainPressureswitchInputStrai nerReverseosmosismodule(RO module)CheckvalveFlowrestrictorDual wavelength UV photooxidation module (185/254 nm)Pure waterqualitysensorPure waterdispenseStoragetankPure (Grade 2) water dispense pumpDeionizationmoduleRecirculationpumpS huntingrestrictorRecirculationvalvePolis hingmoduleProtectivefilterUltrapurewater qualitysensorUltrapure waterdispense valveUltrapure waterdispenseFinal pointof-use filter crystal B Trace crystal B HPLC crystal B BioFlow diagramsSpecificationsPurified water specificationsCrystal B TraceCrystal B HPLCC rystal B BioPure (Grade 2)

6 water resistivity>10 M x cm>10 M x cm>10 M x cmPure (Grade 2) water conductivity< S/cm< S/cm< S/cmUltrapure (Grade 1) water M x M x M x cmUltrapure (Grade 1) water S/cmTOC5 10 ppb<2 ppb<2 ppbRNase < ng/mLDNase <4 pg/ LBacteria< 1 cfu/mL< 1 cfu/mL< 1 cfu/mLEndotoxins< EU/mL< EU/mL< EU/mLParticles > m<1/ per mL<1/ per mL<1/ per mLNominal flow, pure water (to storage tank)10 L/h10 L/h10 L/hNominal dispense flow, ultrapure water2 L/min2 L/min2 L/minNominal dispense flow, pure water4 L/min4 L/min4 L/minDeionization module life (standard module)1 m31 m31 m3 Recovery>30 %>30 %>30 %Dimensions (WxDxH), cm50x40x6050x40x6050x40x60 Storage tank25 L25 L25 LTank dimensions (WxDxH), cm30x25x5030x25x5030x25x50 Feed water 5 5 5 barFeed water conductivity< 900 S/cm< 900 S/cm< 900 S/cmApplicationsApplicationCrystal B TraceCrystal BHPLCC rystal BBioReagent preparation Ion chromatography ICP-MS Atomic absorption spectrophotometry with graphite atomizer ICP-OES HPLC Gas chromatography Total Organic Carbon measurement Flow cytometry Cell and tissue culture Molecular biology 5 ConsumablesPart numberDescriptionReplacement criteriaComments10019 Replacement pre-filter set, crystal BFilter life counter is zero or the filter is clogged 10310 Replacement deionization module DI Err message is shown, or water conductivity is consistently > S/cm 10029 Replacement polishing moduleEvery 1 2 years, depending on operation 10011 Replacement sterilization UV bulbAs required (on average every 3 years)

7 Bio systems only10018 Replacement photooxidation UV bulbAs required (on average every 3 years) HPLC and Bio systems10012 Replacement m dispense microfilterEvery 6 12 months Trace and HPLC systems10120 Replacement ultrafilterEvery 6 12 months Bio systems onlyComponentsPart numberAccessoryCrystal B TraceCrystal B HPLCC rystal B Bio10019 Pre-filter set for chlorine and organics reduction+++Boost pump+++Reverse osmosis module+++10310 Deionization module, standard+++10029 Polishing module+++10105 Photo-oxidation module ++10012 Point-of-use microfilter++ 10109 Point-of-use ultrafiltration module +10102UV sterilization module +10106 Integrated TOC monitor option 10103 Removable controller with Bluetooth moduleoptionoptionoptionModelPart numberCrystal B TraceCB-1015 crystal B HPLCCB-1101 crystal B BioCB-1201 Ordering Information6 UltrapUre water systemsCrystal Integrity systems produce ultrapure water directly from tap water .

8 Ultrapure water produced by the crystal Integrity system complies with the requirements for Grade 1 water in accordance with relevant standards (ISO 3696, ASTM, CLSI). The crystal Integrity systems are recommended for laboratories with relatively low consumption of ultrapure water (about 5 litres per day). crystal Integrity systems are available in the following confi-gurations:Integrity HPLC system (P/N CB-1503) produces water with very low organic carbon (TOC) content. This meets the re qui-rements for liquid chromatog-raphy methods. Integrity HPLC water can also be used for some microbiological and molecular biology appli Bio system (P/N CB-1505) produces water with very low organic and RNase/DNase content. This is intended for use in molecular biology, including RNase-sensitive Integrity water is intended for the most demanding applica-tions including, but not limited to: inorganic trace analysis liquid chromatography cell culture molecular biology Ultrapure water produced by an Integrity system , with resistivity of MegaOhm*cm ( S/cm), exceeds requirements of all rel-evant standards (ISO 3696 Grade 1, ASTM Type I, CLSI Type I).

9 Purified water is collected in an in-tegrated storage tank. The recircu-lation system ensures consistent quality of water and reduces total organic carbon (TOC) to very low levels: < , integrated, 5L tank is made of high density polyeth-ylene to minimize contamination. The storage tank is accessible for Integrity systems have a con-troller with a graphic LCD display for water quality indication. The LCD display provides all necessary information about system status, remaining pre-filter life, and pol-ishing module performance. The smart polishing module monitor-ing system provides a reduction in running costs. Users are instructed to replace the polishing module only when the module is close to the end of its service a Bluetooth option (P/N 10103) is installed, the controller can be detached. The Integrity system can be controlled remotely for more convenient operation.

10 All cartridges and filters are eas-ily accessible and no tools are re-quired to replace them. The Integ-rity system can be installed on a Laboratory bench or mounted on the wall to save space. The crystal Integrity has impor-tant safety functions, including:tank filling control tap water pressure control Integrity seriesConsumablesPart numberDescriptionReplacement criteriaComments10019 Replacement pre-filter set, IntegrityFilter life counter is zero or the filter is clogged 10029 Replacement polishing module DI Err message is shown, or water conductivity while dispensing is consistently > S/cm 10011 Replacement sterilization UV bulbAs required (on average every 3 years) Bio systems only10018 Replacement m dispense microfilterAs required (on average every 3 years) HPLC and Bio systems10012 Replacement m dispense microfilterEvery 6 12 months HPLC systems only10120 Replacement ultrafilterEvery 6 12 months Bio systems onlyApplicationsApplicationIntegrityHPLC I ntegrityBioReagent preparation Ion chromatography ICP-MS Atomic absorption spectrophotometry with graphite atomizer ICP-OES HPLC Gas chromatography Total Organic Carbon measurement Flow cytometry Cell and tissue culture Molecular biology ComponentsPart numberAccessoryIntegrity HPLCI ntegrityBio10019 Pre-filter set for chlorine and organics reduction reduction++Reverse osmosis module++10029 Polishing module++10105 Photo-oxidation module++10012 Point-of-use microfilter+ 10109 Point-of-use ultrafiltration module +10102UV sterilization module +10106 Integrated TOC monitoroption 10103 Removable controller with Bluetooth moduleoptionoptionUV sterilization module (254 nm)