Transcription of LC-MSの基礎ガイド - SHIMADZU
1 LC-MS 604-8511 1 03 3219- 5631 5616 5685 06 6373- 6541 6556 011 700-6605 022 221-6231 024 939-3790 029 851- 8511 8515 048 646- 0095 0081 045 311- 4106 4615 054 285-0124 052 565- 7521 7531 075 823- 1604 1603 078 331-9665 086 221-2511 087 823-6623 082 248-4312 092 283- 3332 3334 2019 3 101-8448530-0012060-0807980-0021963-8877 305-0031330-0843220-0004422-8062450-0001 604-8445650-0033700-0826760-0017730-0036 812-0039 1 3 1 1-4 14 2 8-1 9 2 9-27 12 6-7 2 3 17 - 1 1-41 8 2 8-29 3 7 2 1-1 2 1 47-1 19 1 93 9 3-10 6 1 6-1 NK 9 4-25 15 4-20 4
2 0120-131691IP 075 813-1691 TM LCMS Qarray UF-Lens UFsweeper UFaccumulation UFgrating Liquid Chromatograph Mass SpectrometryLC-MS 1 LC-MS 2LC MS LC-MS 2GC-MS 4LC-MS 5 2 LC-MS 6LC-MS 6LC-MS 8 ESI 8 APCI 10 ESI APCI 11LC-MS 12 3 MS 13 13 14 Q 15 I T 16 TOF 17 18 4 MS/MS 19 MS/MS 19MS/MS 21 Q/Q 21 Q/TOF 22 MS/MS 23 2 1 LC-MS LC-MS LC MS LC LC-MS HILIC LC-MS LC MS LC-MS LC 1 1900 LC
3 1 LC 1 LC HPLC UHPLC MW HILIC HILIC S E C SEC 1 LC 1 LC LC 2 3LC
4 2 LC LC 3 LC MS m/z m/z 3 MS 3 LC-MS 2 LC m/z050 100 150 200 250 300 350 ELSD RID FLD UV-VIS ECD4GC GC EI EI EI
5 GC 4 LC GC LC LC-MS ESI ESI APCI APPI LC 2 EI EI 4 1001,00010,000100,000LC-MS ESI LC-MS APPI LC-MS APCI GC-MS EI MALDIGC-MS Peaks 1.
6 Salicylic Acid 2. Benzoic Acid Acid 4. Phenoxyethanol 5. Methylparaben 6. Dehydroacetic Acid 7. Chlorphenesin 8. Ethylparaben 9. Isopropylparaben10. Propylparaben11. Isobutylparaben12. Butylparaben Nexera UHPLC 5LC-MS LC-MS LC-MS LC-MS LC-MS PPCP
7 6 2 LC-MS 2 LC-MS LC-MS LC LC-MS LC-MS LC-MS LC LC-MS LC-MS 5 LC-MS LC-MS LC LC-MS LC LC-MS m/z HPLCMS 7 A A B B C C436125436125 MS MS LC 1 2 2D LC 1D LC 2 LC-MS 2 LC-MS 2 LC-MS 2 1 1 1 2 2 8 6 A EI B ESI A EI B ESI
8 3773991201008060402001001502002503003504 00 Relative Intensitym/z6112010080604020050100150200 2503003507477911031161301431561711851982 27242256270285301329333341345360 Relative Intensitym/zLC-MS 6 A EI B ESI GC-MS EI M+ EI LC-MS ESI EI M+H+ M+Na+ LC-MS LC ESI APCI NNNNHOHOHOHOHOO B2 C17H20N4O6 [M+H]+[M+Na]
9 + ESI ESI 3 5 kV ESI L/min ESI L/min ESI M+H+ M+NH4+ M-H- M+Cl- 3773991201008060402001001502002503003504 00 Relative Intensitym/z
