Left Atrial Ejection Force：小児正常値と心疾患における変化

1 T19 34 1 19 10 Thesis 1970 Elastance Emax 1) Mechanics 2, 3) Black Box 4 - 7) Left Atrial Ejection Force 1043 18 3 23 3 4 Tissue Doppler Tissue Tracking Mode 8) Rie Kumakura (Department of Pediatric Cardiology, Saitama Medical University, Moroyama, Iruma-gun, Saitama 350 - 0495, Japan) ( Atrial Ejection Force.

2 AEF) AEF AEF 61 ( 10 18 ) 9 7 ( 3 ) 6 AEF Newton 2 ( A )2 AEF AEF BSA HR SVI r p AEF AEF AEF Keywords: AEF T20 Left Atrial Ejection Force 9-12) Senzaki Emax 4) 2 ( Atrial Ejection Force.

3 AEF) Ventricular Ejection Force 1989 Isaaz 13) Manning AEF 14) AEF Sinus Conversion AEF 14) Chinali AEF 15) AEF AEF 61 10 18 N 9 N 7 16 N 3 N 7 1 Sonos 2500 5500 Hewlett Packard Pulse Wave Doppler AEF 14)

4 Newton 2 1 g/cm3 Doppler Echo A Peak 2 A Peak A Peak A T 3 A 4 3 4 1 AEF 5 6 AEF ..(Newton 2 ) 1 ( g/cm3) 2 A T 3 A T 4 AEF ( A )2 5 6 2 Unpaired t test AEF 1 P T21 Left Atrial Ejection Force AEF.

5 1 A A 2 BSA BSA A BSA A HR SVI AEF AEF AEF BSA HR SVI r AEF BSA HR SVI 78 p BSA p HR p SVI p 2 Doppler (VSD) (PDA) HR A (DCM) HR A (CoA) HR A AEF 3 VSD PDA AEF BSA HR SVI 2SD Plot VSD Group VSD PDA p AEF 1 Doppler 1 2 A A ( )

6 10 18 1 6 4 14 3 18 m2 Left Atrial Ejection Force 4A Primar y DCM AEF 2SD Plot DCM 4B DCM Berth 2 Plot AEF 5A CoA AEF p 7 4B 15 DCM AEF DCM 2 AEF AEF AEF AEF BSA HR SVI AEF 6 A 2 3 AEF 4.

7 AEF 4B Berth ACE 2 HR b/ 98 23111 15*121 8*123 18*MVA cm2 * * peak cm/s 96 17106 28111 1591 35A peak cm/s 61 1580 17*29 7*99 27*SVI ml/m2 47 1442 1426 5*33 5 mmHg 12 40 mmHgHR; MVA; E/A peak; E/A SVI; *p vs T23 Left Atrial Ejection Force BSA AEF 2 HR SVI BSA HR SVI BSA 2 A AEF 16-18) Frank-Staring A HR 18, 19) HR Positive Force-Frequency Relation Passive HR AEF SVI AEF SVI A A 19 - 23)

8 Doppler Echo E A SVI AEF SVI SVI A SVI Stiffness SVI A SVI AEF AEF HR SVI 78 AEF AEF VSD PDA AEF Primar y DCM AEF AEF VSD PDA AEF BSA A Control A 400 26) 3 A DCM AEF 1 AEF DCM Doppler Reverse A 27) Total AEF Elastance 16) DCM 5.

9 AEF 5B 6 T24 Left Atrial Ejection Force CoA CoA AEF 4) AEF A Compliance 26) AEF Matsuzaki Elastance Elastance 27) AEF 7 15 DCM AEF 7 AEF AEF AEF AEF 40 ( 2004 6 ) 1) S u g a H , S a g a w a K.

10 I n s t a n t a n e o u s p r e s s u r e -volume relationships and their ratio in the excised, suppor ted canine left ventricle. Circ Res. 1974 Jul; 35(1) ) Kass DA, Maughan WL. From Emax to pressure-volume relations: a broader view. Circulation. 1988 Jun;77(6) ) S e n z a k i H , C h e n C H , K a s s D A . S i n g l e - b e a t estimation of end-systolic pressure-volume relation in humans. A new method with the potential for noninvasive application. Circulation. 1996 Nov 15; 94(10) ) Senzaki H, Chen CH, Masutani S, Taketazu M, Kobayashi J, Kobayashi T, et al. Assessment of cardiovascular dynamics by pressure-area relations in pediatric patients with congenital heart disease. J Thorac Cardiovasc Surg.