LIST OF NEW DRUGS APPROVED IN INDIA FROM …

1 LIST OF NEW DRUGS APPROVED IN INDIA FROM 1961 TO 1970 Name of Drug Pharmacological action/ Indication Date of Approval 1 Ephedrine Resonate 50mg Tablet Same as ephedrine, longer duration of action. January- 1961 2 Vasolastine Ampoule (2ml) Enzyme complexes exert a normalising influence on the deamination of amino acids and on lipid metabolism. January- 1961 3 Methychlothiazide Tablet Oral diuretic agent. Longest duration: more sodium excretion less potassium loss. February- 1961 4 O-Ethoxybenzamide 200mg/500mg Dragees Analgesic, Antiphlogistic, & Antipyretic.

2 February- 1961 5 P-Piperidinoethoxy-O-Carbomethoxy Benzophenone Hydrochloride, 5mg/10mg Injection, Tablet & Suppository Antispasmodic and Analgesic. February- 1961 6 Methocarbamol 1 Injection & Tablet Skeletal muscle relaxant. February- 1961 7 Benziquinone Guanyl Hydrazone Thiosemicarbazone (Ambazone) 10mg Troches Powerful oral and pharyngeal disinfectant. March- 1961 8 Metronidazole 250mg Oral Tablet & 500mg Vaginal Tablet Treatment of trichomonal infestations. March- 1961 9 Spiranolactone 100mg Tablet Promotes diuresis in patients with oedema or ascites, resistant or partly resistant to conventional diuretics.

3 March- 1961 10 Triethanalamine Trinitrate Bisphosphate 8mg/16mg Tablets Treatment of Angina pectoris. It is a vasodilator like glyceryl trinitrate. March- 1961 11 Paromomycin 150mg Capsule Antibiotic for amoebiasis. March- 1961 12 Xylometazoline Nasal drops ( & ) solution Nasal decongestant. March- 1961 13 Methdilazine 8mg Tablet & Syrup New long acting Antihistaminic. March- 1961 14 Isoxsuprine 10mg Tablet & Ampoule Peripheral vasodilator. March- 1961 15 Chlorthalidone 100/200mg Tablet A long acting oral diuretic. March- 1961 16 Mepenzolate methylbromite 25mg Tablet Anticholinergic.

4 March- 1961 17 Pipenzolate methylbromide 5mg Tablet Anticholinergic. March- 1961 18 Piperidolate hydrochloride 50mg Capsule Anticholinergic. March- 1961 19 Isopropamide iodide 5/10mg Tablet Anticholinergic. March- 1961 20 Oxymetholone 5mg Tablet Anabolic agent March- 1961 21 Guanethidine (as sulphate) 10/25mg Tablet Antihypertensive April- 1961 22 Methaqualone hydrochloride 150mg Tablet A new non-barbiturate Hypnotic. April- 1961 23 Chlophedianol hydrochloride 5% drops Anti-tussive April- 1961 24 N-Acetyl-Sulphamethoxy Pyridiazine (Pediatric suspension) Long acting sulpha drug similar to Lederkyn.

5 It is tasteless and more acceptable to children. April- 1961 25 Fibrinolysin (human) 50000 & 100000 units To promote the dissolution of intravenous thrombi. April- 1961 26 Chloramphenicol Palmitoyl Glycolate Suspension For pediatric use. May- 1961 27 Oxyphencyclamine Hcl. 10mg Tablet Powerful anticholinergic agent. May- 1961 28 Fluphenazene Tablet Anxiety & Tension only. May- 1961 29 Norethindrone acetate 5mg Tablet Twice as potent as the parent drug. June- 1961 30 Hydroxycobalamine Injection Same as Vitamin B12. July- 1961 31 Protokylol Hydrochloride Injection ( ) & Tablet (2mg) Bronchodilator, antiasthmatic.

6 July- 1961 32 Sodium-Iron Edetate 55mg Syrup Iron chelate-EDTA August- 1961 33 Betamethasone Tablet A corticosteroid. August- 1961 34 Dexamethasone Trimethyl Acetate Ointment (Ophth.) New salt for topical formulation. August- 1961 35 Metformin Hcl. ( ) Tablet Oral hypoglycemic agent. September- 1961 36 Chlorprothixene 50mg Tablet & 50mg Vial Anti depressant. September- 1961 37 Pipazethate 20mg Dragee & 40mg/ml Drops Anti-tussive September- 1961 38 Pivazide 50mg Tablet Cardiac drug-reduces intensity & frequency of anginal attacks. September- 1961 39 Diphenhydramine (as methyl sulpho methylate / methyl sulphate) 60mg Tablet & 480mg/100ml Syrup Anti-histaminic.

7 September- 1961 40 Edrophonium Chloride (10mg in 1cc) Ampoule Cholinergic & curare antagonist. October- 1961 41 Oxyphenbutazone Tablet Anti-inflammatory, antipyretic. November- 1961 42 2-Thymyloxy Methyl Glyoxalidine Hcl. ( ) Vasoconstrictor. November- 1961 Nasal drops 43 Phenelzine Dihydrogen Sulphate Tablet Anti-depressant. November- 1961 44 Hamycin Vaginal Tablet & Suspension Antifungal antibiotic. November- 1961 45 Dequalinium Acetate Bacteriostatic. November- 1961 46 Ethosuximide Tablet (250mg) & Syrup (250mg/5ml) Anticonvulsant for petitmal epilepsy. December- 1961 47 Pimaricin 50mg Vaginal Tablet Anti fungal antibiotic for "Streptomyces natalensis".

8 December- 1961 48 Kanamycin Sulphate Vials of 2cc ( ) Antibiotic for cases resistant to other antibiotic, urinary tracks staphylococcus infections. December- 1961 49 Prothipendyl Hydrochloride 20mg Dragee Psycho sedative & Tranquiliser-relaxes the autonomous system. January-1962 50 Ethionamide 250mg Tablet Anti-Tuberculosis drug, in cases resistant to other DRUGS . February-1962 51 Nealbarbitone 60mg/200mg Tablet Barbiturates with more sedative, less hypnotic effect. February-1962 52 Cyclopenthiazide Tablet Non-mercurial oral diuretic & hypotensive. February-1962 53 Polythiazide 2mg Tablet Non-mercurial oral diuretic & antihypertensive.

9 February-1962 54 Trypsin-Kallikrein Inactivator (5000 ) Ampoule Inactivates trypsin & Kallikrein-indicated in pancreatitis. February-1962 55 Sulpha-dimethyl Oxazole (Sulfamoxole) Tablet Intermediate acting sulpha drug. March-1962 56 Ferrous Ethylene Diamine Tetra Acetate Trihydrate, 25mg & 50mg Drops Oral iron compound (chelate form). March-1962 57 Bismuth Aluminate Tablet New bismuth salt (antacid). April-1962 58 Hexadimethrine Bromide ( for 100 USP units of Heparin) 10mg/ml & 10ml Vials Heparin antagonist. April-1962 59 Sorbide Nitrate 10mg Tablet Coronary vasodilator.

10 April-1962 60 Cyproheptadine Hcl. (4mg) Tablet & (2mg/ml) Syrup Anti-histaminic, anti-serotonin. April-1962 61 Pamabrom 50mg Tablet Diuretic. April-1962 62 Dexamethasone Sodium Metasulphobenzoate Injection Corticosteroid, anti-inflammatory. April-1962 63 N-N-decamethylene-N-N-decamethylene-bis- amino quinaldine (Salvizol), Loz. & Oint. Anti-bacterial. May-1962 64 Iron-Sorbitol Citric Acid Complex 2ml Injection Haematinic-Parentral iron (Colloidal iron complex). May-1962 65 Nandrolone Decanoate Injection Anabolic effect, depot effect. May-1962 66 Clidinium Bromide Tablet Anti-cholinergic.