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1 14C 14C URL URL URL URL Most of the summaries and evaluations contained in this report are based on unpublished proprietary data submitted for registration to the Ministry of Agriculture, Forestry and Fisheries, Japan. A registration authority outside of Japan should not grant a registration on the basis of an evaluation unless it has first received authorization for such use from the owner of the data submitted to the Ministry of Agriculture, Forestry and Fisheries, Japan or has received the data on which the summaries are based, either from the owner of the data or from a second party that has obtained permission from the owner of the data for this purpose.

2 I.. 1 1.. 1 .. 1 .. 1 .. 1 ADI ARfD .. 1 .. 1 .. 3 .. 3 3 1 .. 4 2.. 4 II.. 7 1.. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 7 .. 8 .. 8 .. 8 .. 8 .. 8 .. 8 .. 8 .. 8 .. 9 2..10 ..10 ..10 ..10 ..10 BSA ..10 TSA .. 11 .. 11 ..12 ..12 ..12 ..13 ..13 ..13 ..13 ..13 ..15 ..15 ..15 ..16 ..17 ..17 ..17 ..21 ..23 ..26 ..27 ..30 ..32 ..33 ..37 ..40 ADI ARfD ..41.

3 43 ..43 ..43 ..43 ..45 ..45 ..45 ..50 ..62 ..62 ..62 ..69 ..69 ..70 ..70 ..74 ..76 ..76 ..76 ..76 ..76 ..76 ..77 ..77 TSA ..85 ..86 ..89 ..91 ..92 ..93 BSA ..93 TSA ..94 ..94 ..94 ..94 ..97 ..97 ..98 ..98 ..98 ..98 .. 100 .. 100 .. 101 TSA .. 101 .. 102 .. 103 .. 103 .. 104 .. 104 .. 105 .. 105 .. 105 .. 107 .. 108 1 .. 109 2 .. 114 3 .. 117 1 I. I.

4 1. 23 82 26 2 26 % 12 11 24 12 8147 13 10 10 13 3986 14 1 10 13 3987 14 1 10 13 3988 ADI ARfD 15 48 ADI ARfD 27 12 22 ADI mg/kg / ARfD mg/kg 27 12 22 943 URL 22 233 29 4 11 29 2 I. 176 BSA 3,4,4- -3- -1- (ppm) 1) 3 2) 3 2) 30 2) 3 2) 30 2) 3 2) 2 2) 2 2) 2 2) 2 2) 9 2) 9 2) 9 2) 9 2) 2 2) 2 2) 9 2) 3 2) 3 2) 2 2) 2 2) 2 2) 30 2) 3 2) 3 2) 2 2) 2 2) 30 1) 1) 1) 2) 1) 3 I.

5 1) 1 1) 1) 1 2) 2) 2 2) 2) 30 2) 2) 2) 2) 2) 2) 9 1) 26 2 26 2) 29 4 11 0411 1 URL 28 5 9 28 57 43 g/L URL 28 11 14 28 105 mg/L URL 4 I. 3 1 3 1 3 1 1 3 1 2 3 1 3 3 1 4 3 1 5 3 1 6 3 1 7 3 1 8 3 1 9 10 3 1 10 2.

6 % 29 4 11 23931 5 I. 5- -2-(3,4,4- -3- -1- )-1,3- % % 20 30 kg/10 a 1 1 20 kg/10 a 1) 2) 3) 4) 5) 6 I. 1) 2) 3) 4) 500 g 1 kg 2 kg 3 kg 5 kg 10 kg 20 kg 7 II.

7 1. II. 1. 5- -2-(3,4,4- -3- -1- )-1,3- fluensulfone ISO IUPAC CAS 5-chloro-2-(3,4,4-trifluorobut-3-en-1-yl sulfonyl)-1,3-thiazole 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-y l)sulfonyl]thiazole CAS No. 318290-98-1 MCW 2 C7H5 ClF3NO2S2 SNClSO2 FFF MAI-08012 8 II. 1. % % % 9 II.

8 1. 29 4 2013 25 2014 26 FAO/WHO JMPR 2015 27 Codex 10 II. 2. 2. OECD109 g/cm3 (20 C) OECD102 DSC C OECD103 DSC 283 C OECD 104 10-2 Pa (25 C) OECD113 DSC (25 150 C) OECD 105 545 mg/L (20 C) n- OECD105 g/L (20 C) 356 g/L (20 C) 306 g/L (20 C) 350 g/L (20 C) 359 g/L (20 C) n g/L (20 C) 351 g/L (20 C) (pKa) ACD / pKa pH 4 9 / (log Pow) OECD 117 HPLC (25 C) OECD 111 (50 C pH 4 pH 7 pH 9 5 ) 12 8147 11 (pH 7 25 C W/m2 300 400 nm) BSA IUPAC 3,4,4-trifluorobut-3-en-1-ylsulfonic acid HO3 SFFF 11 II.

9 2. BSA OECD 104 10-5 Pa (25 C) OECD 105 581 g/L (20 C) n 1,900 mg/L ( C) BSA / OECD 107 log Pow = -2 4 log Pow n- n- log Pow TSA IUPAC 5-chloro-1,3-thiazole-2-sulfonic acid SNClSO3H TSA OECD 104 10-6 Pa ( C) OECD 105 446 g/L (20 C) n 128 mg/L (22 C) TSA / OECD 107 log Pow = -2 4 log Pow n- n- log Pow % 13 3987 50 7 25 750 1700 m 850 1700 m 500 850 m 300 500 m 63 300 m m % % % % % % 35 2 3 71 13 3987 % 12 II.

10 2. pH 35 2 3 71 3 20 30 kg/10 a 1 1 20 kg/10 a 25 303 23 186 13 II. 2. HPLC UV HPLC UV % r n=5 RSD n=5 % BSA TSA / 1/1 v/v C18 LC-MS-MS BSA TSA (mg/kg) (mg/kg) (%) RSDr (%) ( ) 9 93 9 93 ( ) 9 90 9 89 ( ) 9 98 9 89 ( ) 9 91 9 94 14 II.