Material Safety Data Sheet - Cardinal Health

1 Material Safety data Sheet MSDS Number:1087957 Revision date:09/02/2003 Print date:09/02/2003 1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION MSDS Number:1087957 Product name:Nitroglycerin in 5% Dextrose InjectionProduct code:1A0692, 1A0694, 1A0696, JA0694, NDC 0338-1047-02, NDC 0338-1049-02, NDC 0038-1051-02 Synonyms:NoneChemical Family:Cardiovascular drugProduct Type:Regulated Prescription DrugContainer Information:250 ml glass containerProduct Use:Pharmaceutical Supplier:BAXTER HEALTHCARE CORPORATION DEERFIELD, ILLINOIS 60015 (800) 422-9837 or (847) 948-4770 Emergency telephone number.

2 PROSAR: USA (888) 990-0996 OUTSIDE USA (615)917-6114 CHEMTREC: USA (800) 424-9300 OUTSIDE USA (743)741-6089 2. COMPOSITION/INFORMATION ON INGREDIENTS ComponentWeight %UN Number:Classification:Nitroglycerin (desensitized); UN0144 (solution in alcohol with more than 1 percent but not more than 10 percent nitroglycerin); UN1204 (solution in alcohol with not more than 1 percent nitroglycerin); UN3064 (solution in alcohol with more than 1 percent but not more than 5 percent nitroglycerin); UN3319 (desensitized, solid); UN3343 (mixture, desensitized, liquid, flammable)E;R3 N;R51-53 R33 T+.

3 R26/27/28 Dextrose 5996-10-15 NoneNoneEthyl Alcohol 64-17-5<1UN1170F;R11 Citric Acid Anhydrous 77-92-9<1 NoneXi; R38 Water 7732-18-5>94 NoneNone 3. HAZARDS IDENTIFICATION Emergency overview:Product contains no specific hazards other than therapeutic effects. Principle routes of exposure:Absorbed through skin. Eye contact. id: 1087957_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Product name: Nitroglycerin in 5% Dextrose Injection Inhalation:Inhalation not likely under normal use conditions.

4 Ingestion:Nervous system effects (headache, dizziness, light headedness). Cardiovascular effects (may include fluctuations in heart rate, changes in blood pressure, chest pain). Skin contact:Nervous system effects (headache, dizziness, light headedness). Cardiovascular effects (may include fluctuations in heart rate, changes in blood pressure, chest pain). Eye contact:No known effect according to our database. 4. FIRST AID MEASURES Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration.

5 If breathing is difficult, give oxygen. Get medical attention if symptoms appear. Skin contact:Wash contaminated skin with soap and water. Get medical attention if irritation develops. Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this Material are swallowed, call a physician immediately. Eye contact:In case of contact, immediately flush eyes with plenty of water for at least 15 minutes.

6 Get medical attention if irritation develops. Notes to physician:See patient package insert in shipping carton for complete information. 5. FIRE FIGHTING MEASURES Suitable extinguishing media:Use foam or all purpose dry chemicals to extinguish. Special protective equipment for firefighters:Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear. Specific methods:No information availableFlash point:Not determinedAutoignition temperature:Not applicableFlammable limits in air-lower (%):Not applicableFlammable limits in air-upper (%):Not applicable 6.

7 ACCIDENTAL RELEASE MEASURES Personal precautions:Use suitable protective equipment (Section 8). Follow all fire fighting procedures (Section 5). Environmental precautions:No information available. Methods for cleaning up:If emergency personnel are unavailable, contain spilled Material . For small spills add absorbent (soil may be used in the absence of other suitable materials) scoop up Material and place in a sealed, liquid-proof container for disposal. For large spills dike spilled Material or otherwise contain Material to ensure runoff does not reach a waterway.

8 Place spilled Material in an appropriate container for disposal. Product id: 1087957_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Product name: Nitroglycerin in 5% Dextrose Injection 7. HANDLING AND STORAGE Handling: Technical measures/precautions:Do not ingest. Wash thoroughly after handling. Storage: Technical measures/storage conditions:Keep containers tightly closed in a cool, well-ventilated place. Store at room temperature 25 C (77 F).

9 Protect from freezing. Avoid excessive heat. Incompatible products:No special restrictions on storage with other products. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Occupational Exposure Limits ComponentOSHA- Time Weighted Average:OSHA- Short Term Exposure Limit:OSHA- Ceiling LimitsACGIH- Time Weighted Average:ACGIH- Short Term Exposure Limit:ACGIH- Ceiling Limit Value:Nitroglycerin ppm Ceiling; 2 mg/m ppm TWANoneNoneDextrose 5996-10-1 NoneNoneNoneNoneNoneNoneEthyl Alcohol 64-17-51000 ppm TWA.

10 1900 mg/m TWANoneNone1000 ppm TWANoneNoneCitric Acid Anhydrous 77-92-9 NoneNoneNoneNoneNoneNoneWater 7732-18-5 NoneNoneNoneNoneNoneNone Engineering measures:No special containment is required. Provide general or local exhaust ventilation. Personal protective equipment: Respiratory protection:Perform exposure monitoring for this product and its components to ensure that employees are not exposed to levels greater than applicable regulatory limits. If exposure levels exceed regulatory limits, implement a respiratory protection program including respiratory protection that is in compliance with OSHA 29 (in the US) or equivalent regulation in other regions.