Material Safety Data Sheet ( MSDS ) - Chloroform

1 msds - ( msds ) :ChloroformCatalogCodes:SLC1888,SLC5044 CAS#:67-66-3 RTECS:FS9100000 TSCA:TSCA8(b)inventory:ChloroformCI# :Trichloromethane;Methane,trichlor-Chemi calName:ChloroformChemicalFormula:CHCl3 ,TAMILNADU,INDIA24 HourHealthEmergency(91)8939878447(91)944 4038694 TransportationEmergencyPhone(91) :NameCAS#%byWeightChloroform67-66-3100 ToxicologicalDataonIngredients:Chlorofor m:ORAL(LD50):Acute:695mg/kg[Rat].36mg/kg [Mouse].820mg/kg[Guineapig].DERMAL(LD50) :Acute:>20000mg/kg[Rabbit].VAPOR(LC50):A cute:47702mg/m4hours[Rat]. :Hazardousincaseofskincontact(irritant), ofeyecontact(irritant),ofingestion, (permeator).PotentialChronicHealthEffect s:CARCINOGENICEFFECTS:Classified+(Proven .) (Provenforanimal.)byACGIH,2B(Possiblefor human.) (Someevidence.)

2 ,liver, , :Incaseofcontact, :Ifinhaled, , , ,tie, , , :Itmaybehazardoustothepersonprovidingaid togivemouth-to-mouthresuscitationwhenthe inhaledmaterialistoxic, , ,tie, : ,lithium,perchlorate,pentoxide,bis(dimet hylamino)dimethylstannane,potassium,pota ssium-sodiumalloy,sodium(orsodiumhydroxi deorsodiummethoxide), , , , , ; :TWA:10(ppm)[Australia]InhalationTWA:2(p pm)fromOSHA(PEL)[UnitedStates] (mg/m3)fromNIOSHI nhalationSTEL:2(ppm) (mg/m3)fromOSHA(PEL)[UnitedStates]Inhala tionTWA:10(ppm)fromACGIH(TLV)[UnitedStat es][1999]InhalationTWA:2(ppm)[UnitedKing dom(UK)] (mg/m3)[UnitedKingdom(UK)] (1%soln/water) :61 C( F) C( F) C(506 F) (Water=1) (@20 C) (Air=1) :85 :Theproductismoresolubleinoil;log(oil/wa ter)=2 Ionicity(inWater) :Incompatiblematerials,LightIncompatibil itywithvarioussubstances:Reactivewithmet als, ,acetone,disilane,fluorine,strongbasesan dreactivemetals(aluminum,magnesiuminpowd eredform), :Itwillattacksomeformsofplastics,rubber, : (LD50):36mg/kg[Mouse].

3 Acutedermaltoxicity(LD50):>20000mg/kg[Ra bbit].Acutetoxicityofthevapor(LC50):4770 2mg/m4hours[Rat].3 ChronicEffectsonHumans:CARCINOGENICEFFEC TS:Classified+(Proven.) (Provenforanimal.)byACGIH,2B(Possiblefor human.) (Someevidence.) :kidneys,liver, :Hazardousincaseofskincontact(irritant), ofingestion, (permeator). :Mayaffectgeneticmaterial(possiblemutang en)andcauseadversereproductiveeffects(em bryotoxicityandfetotoxicity)Suspectedcar cinogen(tumorigenic) :passestheplacentalbarrier, :AcutePotentialHealthEffects: :Causeseyeirritation, :Causesirritationoftherespiratorysystem( mucousmembranes).Mayaffectbehavior/Nervo ussystem(CNSdepressant,fatigue,dizziness ,nervousness,giddiness,euphoria,lossofco ordinationMSDS- ,weakness,hallucinations,musclecontracti on/spasticity,generalanesthetic,spasticp aralysis,headache),anorexia(neurological andgastrointestinalsymtomsresemblingchro nicalcoholism), ,kidneysandgastrointestinaltract(nausea, vomiting).

4 Ingestion:Causesgastrointestinaltractirr itation(nausea,vomiting).Mayaffecttheliv er,urinarysystem(kidneys),respiration,be havior/nervoussystem(symptomssimilartoin halation), :Inhalation:Prolongedorrepeatedinhalatio nmayaffecttheliver(hepatitis,jaundice,he patocellularnecrosis),metabolism(weightl oss),respiration(fibrosis,pneumoconoisis ),behavior/centralnervoussystem(symptoms similartoacuteinhalation),blood,musculos keletalsystem, :Prolongedorrepeatedingestionmayaffectth eliver,kidneys,metabolism(weightloss),en docrinesystem(spleen),blood(changesincel lcount). :Ecotoxicityinwater(LC50) [Trout].BOD5 , :Wastemustbedisposedofinaccordancewithfe deral, ::ChloroformUNNA:UN1888PG: :Thisproductcontainsthefollowingingredie ntsforwhichtheStateofCaliforniahasfoundt ocausecancer,birthdefectsorotherreproduc tiveharm, (nosignificantrisklevel): (value) msds - :Thisproductcontainsthefollowingingredie ntsforwhichtheStateofCaliforniahasfoundt ocausecancerwhichwouldrequireawarningund erthestatute:ChloroformNewYorkreleaserep ortinglist:ChloroformRhodeIslandRTKhazar doussubstances:ChloroformPennsylvaniaRTK :ChloroformMassachusettsRTK:ChloroformNe wJersey:ChloroformCaliforniaDirector'sLi stofHazardousSubtances(8 CCR339):ChloroformTennessee:ChloroformTS CA8(b)inventory:ChloroformTSCA8(d)HandSd atareporting: Chloroform :effective:6/1/87 .

5 Sunset:6/1/97 SARA302/304/311/312extremelyhazardoussub stances:ChloroformSARA313toxicchemicalno tificationandreleasereporting: Chloroform CERCLA:Hazardoussubstances.: Chloroform :1 0lbs.( )OtherRegulations:OSHA:Hazardousbydefini tionofHazardCommunicationStandard( ). :WHMIS(Canada):CLASSD-1A:Materialcausing immediateandserioustoxiceffects(VERYTOXI C).CLASSD-2A:Materialcausingothertoxicef fects(VERYTOXIC).DSCL(EEC):R20 ( ):HealthHazard:2 FireHazard:0 Reactivity:0 PersonalProtection:hNationalFireProtecti onAssociation( ):Health:2 Flammability:0 Reactivity:0 Specifichazard: :Theinformationandrecommendationscontain edhereinare,tothebestofPureChemicalsGrou pknowledgeandbelief, ' ' ,itistheuser'sresponsibilitytoinsureprop erhealth, ,re-publicationorretransmissionofthisdoc ument,inwholeorinpart,isnotpermitted.