MATERIAL SAFETY DATA SHEET - Nippon Chem

1 Nippon CHEMICAL INDUSTRIAL CO., LTD. Page 1 5. HISHICOLIN PX-4B ( ) 12/01/ 2005. MATERIAL SAFETY data SHEET . [ HISHICOLIN PX-4B ]. MSDS No.: 2101060201. Established: 07/09/ 2005. Revised: 12/01/ 2005. 1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION. PRODU CT N AME(GRADES): HISHICOLIN PX-4B. NAME OF MANU F ACTU RER: NIPP ON CHEMICAL INDUSTRIAL CO., LTD. HEAD OFF ICE(ADDRESS): 11-1, 9-chom e, Kam eido, Koto-k u, T ok yo, 136-8515, Japan NAME OF SECT ION: Organic Chem icals Sales Dept., Organic Chem icals Division TEL. +81-3-3636-8048, F AX. +81-3-3636-8132. EMERGEN CY T EL EP HON E: Same phone num ber listed above 2. COMPOSITION/INFORMATION ON INGREDIENTS. SU BST AN CE OR P REP ARAT ION: Substance CHEMICAL N AME(GEN ERIC N AME): Tetra-n-butylphosphonium brom ide IN GREDIENT S AN D COMP OSIT ION: min 9 %.

2 CHEMICAL FORMU L A: (C4H9)4P+ Br- CAS N o.: 3115-68-2. JAP AN ESE OFF ICIAL GAZETT E SERIAL N o.: (2)-3487. TSCA IN VENT ORY: LISTED. EIN ECS N o.: 221-487-1. IN GREDIENT S CONT RIBU TIN G T O T HE HAZARD: INPU RIT IES CONT RIBUT IN G T O T HE HAZARD: None 3. HAZARDS IDENTIFICATION. MOST IMPORT ANT HAZARDS: Irritant HU MAN HEAL TH: Have acute toxicity. Irritating to skin, mucous mem brane. ENVIRONMENTAL EFF ECT: Have no biodegradation. PHYSICAL AND CHEMICAL HAZARDS: It may be dust explosion. 4. FIRST-AID MEASURES. INHAL AT ION: Immediately have the victim rest covered with blank et and move to a place under fresh air and consult with a physician as soon as possible. In case of respiratory distress or arrest, immediately give rescue breathing to the victim.

3 If inhaled, remove to fresh air. Use a bag valve mask or similar device to perform artificial respiration (rescue breathing) if needed. Get m edical attention. Nippon CHEMICAL INDUSTRIAL CO., LTD. Page 2 5. HISHICOLIN PX-4B ( ) 12/01/ 2005. SKIN CON T ACT: Quickly take off the contaminated cloth or shoes, wash the part of adhesion with soap suds and wash away using a plenty of water, and immediately consult with a physician. EYE CONT ACT: In case of contact, Wash with clean water for at least 15 minutes and consult with a physician. IN GESTION: Administer salt water and force the victim to vomit and lower the body-intak e as much as possible. 5. FIRE-FIGHTING MEASURES. EXT IN GU ISHING MEDIA: Use carbon dioxide, dry chem ical, water spray and sand.

4 SP ECIF IC HAZARDS: Com bustion products phosphorus penta oxide and carbon dioxide. PROT ECT ION F IRE-F IGHT ERS: Use breathing equipment or gas helmet. 6. ACCIDENTAL RELEASE MEASURES. PERSON AL P RECAUT IONS: Wear proper protective equipm ent (gloves, SAFETY goggles etc.). MET HODS F OR CL EAN IN G UP: Small spills: Carefully sweep up. Place in a bag and hold for waste disposal. Use suitable protective equipm ent (gloves, SAFETY goggles etc.). Large spills: Cover with plastic SHEET to minimize spreading and collect spilled m aterial in appropriate container for disposal. 7. HANDLING AND STORAGE. HANDLING: TECHN ICAL MEASURES: Do not get in eyes, on skin or on clothing. W ear proper protective equipment uring use. PRECAUT IONS: Preclude generation of dusts of the product.

5 SAF E HANDL ING ADVICE: Wear personal protective equipment. ST ORAGE: Store in a dark, cool place keeping isolated from inflammable substances, com bustible substances and explosive substances as avoiding mixing with oxidizing agents. INCOMPAT IVL E PRODUCT S: Metal, Basic chemicals. PACKAGING MAT ERIAL S: Store in a glass jar or vinyl bag. Avoid contact with metallic container. Nippon CHEMICAL INDUSTRIAL CO., LTD. Page 3 5. HISHICOLIN PX-4B ( ) 12/01/ 2005. 8. EXPOSURE CONTROL/PERSONAL PROTECTION. EN GIN EERING MEASU RES: Provide local exhaust ventilation system. Ventilation equipm ent should be explosion-resistant if explosive concentrations of MATERIAL are present. Ensure compliance with applicable exposure limits. PERSON AL P ROT ECT IVE EQU IP MENT: RESP IRAT ORY PROT ECTION: Use a dust-proof mask.

6 HAND PROTECTION: Protective gloves. EYE P ROT ECT ION:Protective goggles or face mask. SKIN AND BODY P ROT ECT ION: It is desired to use dust-resisting protective equipment. 9. PHYSICAL AND CHEMICAL PROPERTIES. PHYSICAL ST AT E: White solid COL OU R: White ODOR: Odorless BOILING POIN T: MELT IN G P OINT: 112 . FLASH P OINT: 230 . IGNITION POIN T: 290 . DEN SITY: 0. 604 g/cm 3 (20 ). SOLU BIL IT Y: Water- soluble; Other- soluble in alcohol, acetone, chloroform. 10. PHYSICAL HAZARD (STABILITY & REACTIVITY). STABILIT Y: If it touches metal for long term, they get coloration. CON DITION TO AVOID: HAZARDOU S DECOMPOSIT ION P RODU CT S: 11. TOXICOLOGICAL INFORMATION. ACUT E TOXICIT Y: ORAL: 676mg/kg rat LD50. Dermal : 700 mg/kg rabbit LD50.

7 Dermal: < 2,000 mg/kg rat LD50. Inhalation: < 3 mg/kg (1Hr) rat LD50. IV injection: 56 mg/kg mouse LD50. LOCAL EF F ECTS: Irritant to sk in and mucous m em brane. Nippon CHEMICAL INDUSTRIAL CO., LTD. Page 4 5. HISHICOLIN PX-4B ( ) 12/01/ 2005. Acridity (Skin) 500 mg ; Rabbit Acridity (Eye) 100 ul/24Hr ; Rabbit Ames test Salmonella, bacillus coli; Negative MUTAGENICIT Y: Ames test (Salmonella, bacillus coli); Negative 12. ECOLOGICAL INFORMATION. PERSIST EN CE/DEGRADABIL ITY: Degradability Not finding (in sludge). ECOT OXCIT Y: Do not allow MATERIAL to released to the environm ent without proper governm ental perm it. Toxic to fish: Kill fish Tlm48; < 1,000 mg/L. 13. DISPOSAL CONSIDERATION. Disposal is made by means of incineration by an incinerator with waste gas cleaning equipment.

8 At that time, phosphorus penta oxide, hydrogen brom ide, and carbon oxide are produced. 14. TRANSPORT INFORMATION. PROP ER SHIP PIN G N AME: ORGANOPHOSPHORUS COMPOUND, TOXIC, SOL ID, N. (T tra n-butylphosphonium brom ide). UN CL ASS: UN N o.: 3464. PACKIN G GROUP: III. 15. REGULATORY INFORMATION. REGUL AT ION S: LAW FOR SAF ETY OF VESSELS: Enforcem ent regulation, Article 2 (Hazardous MATERIAL ), Notice; schedule , Poison class. AVIAT ION LAW: Enforcement regulation; Article 194, Notice; schedule , Poison. 16. OTHER INFORMATION. REF EREN CES: Notices . 1) The MATERIAL SAFETY data SHEET is a brief summary of general precautions necessary for proper use of Our Company Product. For a special use and handling, use upon SAFETY confirm ation and implem entation of the measures suited to the application.

9 2) The contents entered in the MSDS was prepared based on the documents and test data available at the tim e of preparation but does not guarantee at all the descriptions of Nippon CHEMICAL INDUSTRIAL CO., LTD. Page 5 5. HISHICOLIN PX-4B ( ) 12/01/ 2005. Com position/Inform ation on Ingredients, Physical & Chemical Properties and Hazards Identification. 3) Every chemical product may present unknown hazards and should be used with utmost caution. All users should bear the responsibility of setting of the safe use conditions. 4) The information herein is subject to change by new findings such as new literatures and test results and revisions of laws and regulations.