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1 DKIX05R Page 120/12/22 13:16 1 120 30 2 (1) ! ! ! ! ! ! ! ! ! !201 1 Addams, J., Curie, M., Nightingale, F., Einstein, A.,A. 1 201 1 201234120122341201244 DKIX-05R- H-1110 14 3 00 12 30 !DKIX05R Page 220/12/22 13:16 !202 1 32 1899 !

2 2 4 1915 !3 23 1948 !4 43 1968 !5 13 2001 ! 1 202 1 2022345120224234512022455 !203 1 2 3 4 5 1 203 1 20323452032323452032344 DKIX-05R- H-2 DKIX05R Page 320/12/22 13:16 (2) ! !20450 45 % AA BBCCDD33 3A 3 A 204 0 204 0123456789 98765432101234567890123456789 DKIX-05R- H-3 DKIX05R Page 420/12/22 13:16 H-4 DKIX05R Page 520/12/22 13:16 H-5 DKIX05R Page 620/12/22 13:16 H-6 DKIX05R Page 720/12/22 13:16 30 2018 !

3 1 2 600 3 2,600 4 4,600 2 29 2017 ! 10 ! 1 2 3 4 3 1 2 3 4 !4 1 2 3 4 DKIX-05R- H-71 DKIX05R Page 820/12/22 13:16 1 20 2 3 4 6 1 2 3 4 Babinski 7 30 2018 ! 1 2 3 4 !

4 8 , , R. J. 1 2 3 4 DKIX-05R- H-82 DKIX05R Page 920/12/22 13:16 30 2018 ! 65 1 10%2 30%3 50%4 70%10 1 2 3 4 11 1 2 3 4 12 1 2 3 4 DKIX-05R- H-93 DKIX05R Page 1020/12/22 13:16 , bler-Ross, E. 1 2 3 4 14 hepaticencephalopathy 1 2 3 4 15 1 2 3 4 16 1 2 3 4 DKIX-05R- H-104 DKIX05R Page 1120/12/22 13:16 1 2 3 4 18 1 2 3 4 19 1 100mL2 500mL3 1,500mL4 2,500mL20 1 26 28 C2 32 34 C3 38 40 C4 44 46 CDKIX-05R- H-115 DKIX05R Page 1220/12/22 13.

5 16 1 2 3 4 22 1 2 3 4 23 1 2 3 4 24 1 10 15 2 20 25 3 30 35 4 40 45 DKIX-05R- H-126 DKIX05R Page 1320/12/22 13:16 1 2cm2 5cm3 8cm4 11cm26 1 2 3 4 + 27 viral hepatitis DNA 1 A 2 B 3 C 4 E 28 sepsis 1 2 3 4 DKIX-05R- H-137 DKIX05R Page 1420/12/22 13.

6 16 1 2 3 4 30 75 C 1 2 3 4 31 1 2 3 4 32 1 2 3 4 closedquestion DKIX-05R- H-148 DKIX05R Page 1520/12/22 13:16 1 2 3 4 34 incontinenceofurine 1 overflowincontinenceofurine 2 functional urinaryincontinenceofurine 3 urge incontinenceofurine 4 reflexincontinenceofurine 35 1 2 3 4 36 1 2 3 4 DKIX-05R- H-159 DKIX05R Page 1620/12/22 13.

7 16 R 1 10 20 2 30 40 3 50 60 4 70 80 38 1 2 3 4 39 SARS Severe Acute RespiratorySyndrome 1 2 3 4 DKIX-05R- H-1610 DKIX05R Page 1720/12/22 13:16 63 ! lungcancer WHO A 1 2 3 4 41A 24 !

8 180cm 51kg T 20 40 / C 20/ ! 84/ 122/64mmHg ! A 1 2 3 4 H-1711 DKIX05R Page 1820/12/22 13:16 50 ! cirrhosis A 1 2 3 4 43 Cushing cushing syndrome 1 2 3 4 44A 64 ! pneumonia C 24/ 80/ 124/80mmHg SpO2 96% room air!

9 A 1 acquired epidermolysisbullosa2 Sj gren Sj gren ssyndrome3 systemiclupus erythematosus4 Stevens-Johnson Stevens-JohnsonsyndromeDKIX-05R- H-1812 DKIX05R Page 1920/12/22 13:16 1 2 3 4 46 IADL 1 2 3 4 47 1 2 3 4 DKIX-05R- H-1913 DKIX05R Page 2020/12/22 13:16 80 ! hypertension ADL 30 A A 1 2 3 4 30 49 1 2 3 4 50 1 2 3

10 4 DKIX-05R- H-2014 DKIX05R Page 2120/12/22 13:16 MRI 1 2 3 4 52 1 2 3 4 53 1 2 50 3 10 10% 4 75 90 DKIX-05R- H-2115 DKIX05R Page 2220/12/22 13:16 11 ! nephroticsyndrome A 1 2 3 4 55 1 2 3 D 4 56 1 10 2 3 28 2016 !