Minimum PPE Required PPE Requirements Hazardous Drug …

1 Minimum PPE RequiredHandling only - No alterationContained Crush/Split Crush/SplitMinimum PPE Required abacavir (susp) (2)ziagen/epzicom/trizivirLowabacavir (tablet) (2)ziagen/epzicom/trizivirUniversalLowMo derateacitretin (capsule) (3)soriataneUniversalModerateanastrazole (tablet) (1)arimidexLowModerateHighandroid (capsule) (3)methyltestosteroneUniversalModerateap omorphine (inj sq) (2)apomorphineModeratearthotec/cytotec (tablet) (3) diclofenac/misoprostolUniversalLowModera teastagraf XL (capsule) (2)tacrolimusUniversaldo not openavordart (capsule) (3)dutasterideUniversalModerateazathiopr ine (tablet) (2)apomorphineUniversalLowModeratebicalu tamide (tablet) (1)casodexLowModerateHighbrisdelle (capsule) (3)paroxetineUniversalModeratecaprelsa (tablet) (1)vandetanibLowcarbamazepine (suspension) (2)tegretolLowcarbamazepine (tablet) (2)tegretolUniversalLowModeratecarbamaze pine ER (tablet) (2)carbatrol/equatrolUniversalclonazepam (tablet) (3)KlonopinUniversalLowModerateclonazepa m ODT (tablet) (3)KlonopinUniversalcolchicine (capsule) (3)colchicineUniversalModeratecolcrys (tablet) (3)colchicineUniversalLowModeratecrizoti nib (capsule)

2 (1)xalkoriLowdo not opencyclophosphamide (capsule) (1)cyclophosphamideLowHighcyclophosphami de (tablet) (1)cyclophosphamideLowModerateHighcyclos porin (solution) (2)sandimmune/neoral /gengrafLowcyclosporine (capsule) (2)sandimmune/neoral /gengrafUniversalModeratecyclosporine (eye drops) (2)restasisLowdiclofenac/misoprostol (tablet) (3)cytotecUniversalLowModeratedivalproex (tablet) (2)depakoteUniversalDispensed/Common Drug Name (Formulation) and (NIOSH CATEGORY #)Additional InformationUniversal (Green) - handling and disposed of using normal precautions. Low (Yellow) - handle at all times with gloves and appropriate engineering controls.

3 Moderate (Orange) -handle at all times with gloves, gown, eye and face protection (with splash potential) and appropirate engineering controls. High (Red) - double gloves, gown, eye and face protection in addition to any necessary engineering PPE requiredMinimum PPE requiredMinimum PPE Required Open CapsulePPE Requirements Hazardous Drug HandlingTablet Minimum PPE RequiredOther Drug Namedo not split/crushdo not split/ crushdo not split/ crushdo not split/ crushdivalproex ER (tablet) (2)depakote erUniversaldivalproex sprinkle (capsule) (2)depakote sprinklesUniversalModerateella (tablet) (3) ulipristalUniversalLow Moderateemcyt (capsule) (1)estramustineLowHighestradiol (tablet) (2)

4 EstradiolUniversalLowModerateestradiol (transdermal) (2)estradiolLowestrogen, conjugated (cream) (2)premarinLowestrogen, conjugated (tablet) (2)premarin, prem-proUniversalestrogen/progesterone (patch) (2)climara, combipatchLowestropipate (tablet) (2)ogenUniversalLow Moderateetoposide (capsule) (1)toposarLowHighexemestane (tablet) (1)aromasinLowModerateHighfareston (tablet) (1)toremifeneLowModerateHighferriprox (tablet) (2)deferiproneUniversalLow Moderatefinasteride (tablet) (3)proscarUniversalLow Moderatefluconazole (injectable) (3)diflucanHighonly if reproductive risk - if not, universalfluconazole (tablet) (3)diflucanUniversalLow Moderatefluorouracil (cream/solution) (1)adrucil/carac/efudex /fluoroplexModeratechemo rated glovesfluoxymesterone (tablet) (2) fluoxymesteroneUniversalLow Moderateflutamide (capsule) (1)flutamideLowHighfosphenytoin (Inj-IM) (2)cerebyxModeratefosphenytoin (Inj-IV) (2)cerebyxHighganciclovir (Inj) (2)cytoveneHighgeodon (injection) (3)ziprasidoneModerategilenya (capsule) (2)fingolimodUniversalModerategleevac (tablet) (1)imatinibLowhexalen (capsule) (1)

5 AltretamineLowHighhydroxyurea (capsule) (1)droxia/hydreaLowHighicatibant (syringe/sq) (3)firazyrModerateonly if reproductive risk - if not, universaljalyn (capsule) (3) dutasteride/tamsulosinUniversalModeratel amuvudine/zidovudine (tablet) (2) combivir UniversalLowModerateleflunomide (tablet) (2)aravaUniversalletairis (tablet) (3) ambrisentanUniversalletrozole (tablet) (1)femaraLowModerateHighleukeran (tablet) (1)chlorambucilLowModerateHighleuprolide (injection) (1)lupron depot/eligard/ lupanetaModerate/ High (syringe/vial)lomustine (capsule) (1)gleostineLowHighlysodren (tablet) (1)mitotaneLowmatulane (capsule) (1)procarbazineLowHighmedroxyprogesteron e (tablet) (2)proveraUniversalLow Moderatemegestrol (susp) (1)megaceModeratedo not split/crushdo not split/crushdo not split/ crushdo not split/crushdo not split/ crushdo not split/ crushmegestrol (tablet) (1)megaceLowModerateHighmelphalan (tablet) (1)alkeranLowModerateHighmercaptopurine (susp) (1)purinetholModeratemercaptopurine (tablet) (1)purinetholLowModerateHighmethotrexate (tablet) (1)rheumatrexLowModerateHighmethylergono vine (tablet) (3)

6 MethylergonovineUniversalLowModeratemult aq (tablet) (3)dronedaroneUniversalLow Moderatemycophenolate (tablet) (2)cellceptUniversalmycophenolic acid (pwd/recon) (2)mycophenolic acidModeratemyleran (tablet) (1)busulfanLowModerateHighnevirapine (tablet) (2)viramuneUniversalLowModeratenevirapin e ER (tablet) (2)viramune XRUniversalnevirapine Susp (tablet) (2)viramuneLownexavar (tablet) (1)sorafenibLowModerateHighoxcarbazepine (susp) (2)trileptalLowoxcarbazepine (tablet) (2)trileptalUniversalLowModerateoxcarbaz epine ER (tablet) (2)oxtellar XRUniversalpanretin (topical) (3) alitretinoinLowparoxetine (tablet) (3)paxil/pexevaUniversalLow Moderatepaxil (suspension) (3)paroxetineLowpaxil CR (tablet) (3)paroxetineUniversalphenoxybenzamine (capsule) (2)dibenzylineUniversalmoderatephenytoin (suspension) (2)dilantinLowphenytoin (tablet) (2)dilantinUniversalLowModeratephenytoin ER (capsule) (2)dilantin/phenytekUniversaldo not openprogesterone (capsule) (2) prometriumUniversaldo not openprogesterone (intravaginal) (2) first progest Lowpropylthiouracil (tablet) (2)propylthiouracilUniversalLowModeratep ropylthiouracil (tablet) (2)

7 Propecia/proscarUniversalLow Moderatequdexy XR (capsule) (3)topiramateUniversalModerateraloxifene (tablet) (2)evistaUniversalrapamune (solution) (2)sirolimusLowrebetol (solution) (3)ribavirinLowrevlimid (capsule) (2) lenalidomideUniversaldo not openribavirin (capsule) (3)Universaldo not openribavirin (tablet) (3)Universalrisperdal (solution) (2)risperidoneLowrisperdal consta (injection) (2)risperidoneModeraterisperdal M (dissolve tablet) (2)risperidoneUniversalrisperidone (tablet) (2)risperdal UniversalLowModeratesabril (pwd packet) (3) vigabatrinModeratesabril (tablet) (3) vigabatrinUniversalLowModeratesirolimus (tablet) (2)rapamuneUniversalribasphere/moderiba/ copegus/rebetoldo not split/ crushdo not crush/splitdo not split/ crushdo not split/ crushdo not split/ crushdo not split/ crushdo not crush/splitdo not split/ crushspironolactone (tablet) (2)aldactoneUniversalLowModeratesprycel (tablet) (1)dasatinibLowsutent (capsule) (1)sunitinibLowHightabloid (tablet) (1)thioguanineLowModerateHightacrolimus (capsule) (2)prografUniversalModeratetacrolimus (topical) (2)protopticLowtamoxifen (tablet) (1)nolvadex/soltamoxLowModerateHightarce va (tablet)

8 (1)erlotinibLowModerateHightargretin (capsule) (1) bexaroteneLowHightargretin (gel) (1) bexaroteneModeratechemo rated glovestasigna (capsule) (1)nilotinibLowHightemodar (capsule) (1)temozolomideLowHightestosterone (inj- IM) (3)testosteroneModerateonly if reproductive risk - if not, universaltestosterone (transdermal- all forms) (3)striant/testim/androgel androderm/fortestaLowtestred (capsule) (3)methyltestosteroneUniversalModerateto piramate (tablet) (3)topamaxUniversalLowModeratetopiramate sprinkle (capsule) (3)topamaxUniversalModeratetopotecan (capsule) (1)hycamtinLowdo not openTracleer (tablet) (3)bosentanUniversaltretinoin (gel/cream) (3)retin-A/renova/Lowtronkendi XR (capsule) (3)topiramateUniversaldo not openvalcyte (sol - reconstitute) (2) valganciclovirModeratevalganciclovir (tablet) (2) valcyteUniversalvalproic acid (capsule) (3)depakeneUniversalModeratevalproic acid (syrup) (3)depakaneLowvictoza (Inj) (2)liraglutide recombinantModeratevoriconazole (IV) (3) vfendHighonly if reproductive risk - if not, universalvoriconazole (tablet) (3) vfendUniversalLowModeratevotrient (tablet) (1)pazopanibLowwarfarin (tablet) (3)

9 CoumadinUniversalLowModeratexeloda (tablet) (1)capecitabineLowModerateHighzelboraf (tablet) (1)vemurafenibLowzidovudine (capsule) (2)retrovirUniversalModeratezidovudine (solution) (2)retrovirLowzidovudine (tablet) (2)retrovirUniversalLowModerateziprasido ne (capsule) (3)geodonUniversalModeratezirgan (Eye Gel) (2)g