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1 The SEPILIFTTMDPHP efficacy depends on 2 key factors: Selection an amino acid which plays a specific role and is essential in collagen synthesis: hydroxyproline. Bioconversion into a lipoaminoacidform (palmitic chain grafted onto theamino acid) enabling the vectorisationof hydroxyproline directly through the validated active to beused as ingredient in ecological and organic is a hydroxyproline vehicle which moisturises, strengthens and rejuvenates the skin and lips which recover volume, suppleness and former toneACTIVE GIVOBIOTMGCA (Calcium) SEPITONICTMM4 DEEPALINETMPVB SESAFLASHTM SEPIWHITETMMSH SEPICALMTMVG PHYTOAGETM SEPILIFTTMDPHP SEPITONICTMM3 SEPILIFTTMDPHP PHYTOAGETM EXTRAMELTMC MANOLIVATM SEPITONICTMM3 GIVOBIOTMGMn SEPIVITALTM SEPIVINOLTMAll agesRadical Protection & PhotoprotectionNotaThe analytical specifications warranted are only those mentioned on the certificate of analysis supplied with each delivery of the as set forth above, SEPPIC* makes no warranties, whether express, implied or statutory, as to the product which is the subject of this document.

2 Without limiting thegenerality of the foregoing, SEPPIC* makes no warranty of merchantability of the productoroft he fitness of the product for any particular purpose. Buyer assumes all risk and liability resulting from the use or sale of the product, whether singly or in combination withother goods. The information set forth herein is furnished free of charge and is based ontechnical data that SEPPIC* believes to be reliable. It is intended for use by persons havingtechnical skill and at their own discretion and risk. Since conditions of use are outside SEPPIC*'s control, SEPPIC* makes no warranties, express or implied, and assumes no liability in connection with any use of this information. Nothing herein is to be taken as a license to operate under or a recommendation to infringe any check with SEPPIC* that you have the most recent version of this of the AIR LIQUID group. 2007 SEPPIC*SEPPIC being:SEPPIC Kupka C 7, boulevard Franck Kupka92039 Paris La D fense CedexFRANCETel.

3 : +33 (0) 1 55 91 57 00 Fax: +33 (0) 1 55 91 50 50 GIVAUDAN LAVIROTTE , rue Paul CazeneuveBP 8344 69008 LyonFRANCETel.: +33 (0) 4 78 61 55 00 Fax: +33 (0) 4 72 05 60 89 And, depending on the country: SEPPIC , Two Bridges Road, suite 210 Fairfield, New Jersey 07004-1530 USATel.: +1 973 882 5597 Fax: +1 973 882 5178 SEPPIC UK Ltd50 Salisbury RoadPO Box 338 - HounslowTW4 6SH - ENGLANDTel.: +44 208 577 8800 Fax: +44 208 570 2106 SEPPIC ITALIA SrlVia Quarenghi 2720151 MilanoITALYTel.: +39 02 38009110 Fax: +39 02 38009140 SEPPIC ChinaRoom 510 Jin Tai Building58 South Mao Ming RoadShanghai 200020 CHINATel.: +86 (21) 64 66 01 49 Fax: +86 (21) 64 66 11 09 SEPPIC GmbHABC Tower K lnEttore - Bugatti - K ln-PorzGERMANYTel.: +49 (0) 220 3890 3100 Fax: +49 (0) 220 3890 3199 SEPPIC Belgium NVNieuwe Weg 1 Haven 1053B 2070 ZwijndrechtBELGIUM Tel.: +32 3 250 3911 Fax: +32 3 250 50 yearsHormone like From 40 yearsAnti wrinkles & redensifyer& Lightener From 30 yearsAnti-ageing & EnergizerFrom 20 yearsHydration & Glow AQUAXYLTMA targeted treatmentfor each ageDocumentn C2005/GB/03/July2007-Design:GrisSouris-P hotos:Gettyimage-jupiterimageFrom 60 yearsRestructurerSEPILIFTTMDPHPSkin and lips rediscover original former resistance and toneSmoothes wrinklesMoisturisesVolumeeffectA POWERFUL WEAPON AGAINST AGEING Only the formula with 1% SEPILIFTTMDPHP helps to remove wrinkles.

4 The skin grain is visibly changed. Placebo1% SEPILIFTTM DPHP formula 70713% Lipopeptide anti-ageing 0%1%SEPILIFTTM DPHP formula 67670+18%No significant decrease Significant decrease Comparison of different activity against wrinklesAfter 1 month and a half of treatment, the formula with1% of SEPILIFTTMDPHP significantly decreasesthe wrinkle number versus placebo. Its activityagainst wrinkles is clearly better than a lipopetide anti-ageing on the market, statistically inactive versus wrinklesMoisturisesDay 0 Day 42 Placebo3% Lipopeptide reference on the market1% SEPILIFT DPHP (formula 7071)% = reduction in number of wrinklesSkin prints of crow s foot before and after treatmentProtocol:- 42 days of treatment - 1% SEPILIFT DPHP (formula 7071) - versus placebo and an anti-ageing market reference- 20 volunteers crow s foot (average age: 56 years)(1)Lipopeptide = Glycerin and Water and Butylene Glycol and Carbomer and Polysorbate 20 and Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 After only 1 month of treatment, with 1% of SEPILIFTTMDPHP the skin is more flexible, activity against wrinkles and the visible improvement of the skin grainare treatmentAfter 28 days of treatment1% SEPILIFTTMDPHP Skin prints of crow s footProtocol.

5 - Treatment on the half-face 1% SEPILIFTTMDPHP formula 6767- 15 volunteers crow s foot (average age: 50 years) Confirmed activity against wrinklesPlacebo1% SEPILIFTTM DPHP formula 70713% Lipopeptide anti-ageing 0%Placebo1% SEPILIFTTM DPHP formula 67670%+18%No significant decrease Significant decrease Corneometry measurement% = Increased of moisturisationcompared with placebo Clinically proven by 3 major testsBetter performances against all wrinkles: The benefit of a moisturised skin: Moisturising activity Comparison between the SEPILIFTTMDPHP activity and thelipopetide(1)anti-ageing on the market-10%-32%** p < 0,05 Protocol: - 15 days of treatment - 1% SEPILIFTTMDPHP (formula 6831)- Labial mucous membrane of 30 volunteersAfter 15 days of treatment,SEPILIFTTMDPHP reshapes the lips. Better moisturised and restructured, they look plumped. Activity against wrinklesSEPILIFTTMDPHP reduces the width (L)and the depth (P)of lips furrows by 37%Image analysisProtocol: - 15 days of treatment - 1% SEPILIFTTMDPHP (formula 6831)- Labial mucous membrane of 30 volunteersPOLYVALENT MODE OF ACTION Photos of lipsD15, before lipstick applicationD1: 10 minutes after application20%0%15%-10%D15: before ap plicationCorneometry valueTrans Epidermal Water Loss (TEWL) valuein 89%of subjectsin 67%of subjectsin 70%of subjectsVolume effectD15, 10 mn after lipstickapplicationCorneometry, Trans Epidermal Water Loss ( )Protocol.

6 - 15 days of treatment - 1% SEPILIFTTMDPHP (formula 6831)Firming effect+ 14%of collagen fibers contraction (0,001% am SEPILIFTTMDPHP)Protection of extra-cellular dermal matrix + 81% anti-elastase effect (0,05% am(II)SEPILIFTTMDPHP)+ 26%of pro-collagen 1 stimulation(0,0005% am SEPILIFTTMDPHP)+ 46% of TIMP2(III) stimulation (natural inhibitor of MMPs) (0,0005% am SEPILIFTTMDPHP)+ 94% of MMP2(IIII) inhibition (enzymeresponsible for extra-cellular matrixdegradation) (0,0005% am SEPILIFTTMDPHP)Protection of Dermal Epidermal Junction integrity+ 61% of total laminins stimulation ((0,0005% am SEPILIFTTMDPHP)Free-radical scavenging effect+ 85% inhibitor of superoxyde anion ((0,07% am SEPILIFTTMDPHP) Development of wrinkles and crows foot Skin loses structureand moisturecontent1-Weakening of the collagen fiber network2- Degradation of dermal matrix and DEJ(I)3- Free radical-mediated damage to skin cells Flaccid skinLoss of tone and firmnessGlam effect for reshaped lips: Plumping activity123 Triple firming actionSEPILIFTTMDPHP protects and reinforces skin restores the balance of natural anti-ageingdefense for a younger looking (genetic orphoto-induced)Triple ActionIn vivo proven efficacy(I)Dermal Epidermal Junction(II)Active Matter (III) Tissue Inhibitors of Metalloproteinases 2 (IIII)Metalloproteinases 2 PLPLP reventive & curative effects--- Restructuring and moisturising activityLips are ideally restructured.))

7 SEPILIFTTMDPHP improves immediately lips moisturisationand long term restructuring treatmentAfter treatmentCOSMETICAPPLICATIONS SEPILIFTTMDPHP can be incorporatedinto any kind of product designed to combat ageing, wrinkles, tonelessskins or free radical-induced damage. This lipophilic active substance readily disperses in all types of High performance anti-ageing (7071) LANOLTMP(Glycol palmitate - SEPPIC) MONTANOVTM202(Arachidyl alcohol & behenyl alcohol &arachidyl glucoside - SEPPIC) MONTANOVTM82 (Cetearyl alcohol & Coco-glucoside - SEPPIC) Squalene vegetal Polyisobutene MONTANOXTM60 DF (Polysorbate 60 - SEPPIC) Keltrol T SEPILIFTTMDPHP (Dipalmitoyl Hydroxyproline - SEPPIC) Water Chlorphenesin Glycerin SEPIPLUSTM400 (Polyacrylate-13& polyisobutene & polysorbate 20 - SEPPIC) SEPICIDETMLD (Phenoxyethanol- SEPPIC) Fragance TEA 50% pH DATA All tests have shown SEPILIFTTMDPHP tobevery well tolerated. INCI name:Dipalmitoyl hydroxyproline Technical information files availableon CONCENTRATION: 1%