Monitoring of medical literature and the entry of relevant ...

1 Official address Domenico Scarlattilaan 6 1083 HS Amsterdam The Netherlands An agency of the European Union Address for visits and deliveries Refer to Send us a question Go to Telephone +31 (0)88 781 6000 European Medicines agency , 2022. Reproduction is authorised provided the source is acknowledged. 20 May 2022 EMA/517840/2015 Rev 4* Data Analytics and Methods Taskforce Monitoring of medical literature and the entry of relevant information into the EudraVigilance database by the European Medicines agency EMBASE Search Strategies for Substance Groups 1-309, and Herbal Substance Groups 1-100 *Note: Revision 4 includes the following:Correction of the Valeriana (group 310) search string to add the search criterion :tn after the following trade names.

2 ACIDUM PHOSPHORICUM COMPLEXE N 5 , ALLUNADOC , ANTI STRESS N ENTSPANNUNGSBAD , ANTI-STRESS , AP VIII , ARISTOCHOL , ARKOCAPSULE VALERIANA , ASA FOETIDA PENTARKAN , AURUM VALERIANA , AURUMHEEL N TROPFEN , AURUMHEEL-TROPFEN , AVENA COMP. , AVENA VALERIANA , BALDORM , BALDRIAN , BALDRIAN-DISPERT , BALDRIAN-DRAGEES , BALDRIAN-HOPFEN , BALDRIAN-KR UTERTROPFEN , BALDRIAN-RATIOPHARM , BALDRIAN-SEDATIVBAD N , BALDRIAN-TROPFEN , BALDRIAN-TROPFEN BIO-DI T , BALDRIANWURZEL , BALDRIMED , BALDRI NA TINKT RA , BALDURAT , BENOSEN , BERUHIGUNGS DRAGEES MIT BALDRIAN HOPFEN N , BERUHIGUNGS UND EINSCHLAFTEE , BERUHIGUNGS-TEE , BERUHIGUNGS-TROPFEN , BERUHIGUNGSTEE , BERUHIGUNGSTEE VII , BIOCARDE , BIOSEDON , BODIVAL H , BRONCHOFIT EFEU , BRONCHOLITAN , CALM LIFE , CALMEDORON , CALMIKIND , CALMIPLANT , CALMVALERA , CALMY , CARDIOL , CARMITANTA , CIRCOSAN , CIRKUSED , COENRELAX , CORSELECT.

3 CRATAEGUS HEVERT , CUPRUM ACETICUM /ZINCUM VALERIANICUM , DIACARD , DOLESTAN , DORMICALM , DORMIDINA VALERIANA/LUPULO , DORMIKIND , DORMIPLANT , DORMOSYX , DRAGEES BALDRIAN & HOPFEN , DYSTO-LOGE S N , EINSCHLAF-DRAGEES , EINSCHLAF-KAPSELN , EUPHYTOSE , EURIMISK , EUVEGAL , EXIGAN , EXTRASPASMINA , GLICEROVALEROVIT , GOLDEN SEAL DIGESTIVE , GUTNACHT-KR UTERTEE , HARPAGOFORTE , HEDELIX , HELIX AIWA , HEPACYN FRISCHPFLANZEN-ARTISCHOCKE , HERBAL SLEEP , HOVA , HYOSCYAMUS / VALERIANA WELEDA , HYPERFORAT NERVOHOM , INVERMA , KINDINORM , KINDIVAL , KNEIPP BALDRIAN and KNEIPP SCHLAF GUT BALDRIAN Th e following erroneous terms were removed: CRATAEGUS HEVERT, PASSIFLORA The following duplicated terms were removed: BALDRIAN :tn, BALDRIAN-DISPERT :tn, CARDIOL :tn, EUPHYTOSE :tn, HOVA :tn, NOVO-PASSIT :tn, PERSEN :tn, SCHWEDENBITTER :tn, SEDONIUM :tn, VALERIANA :tn, VALMANE :tn Monitoring of medical literature and the entry of relevant information into the EudraVigilance database by the European Medicines agency EMA/517840/2015 Effective date: 1 April 2021 Page 2/386 Table of Contents Table of Contents.

4 2 I. Introduction .. 12 II. General Principles .. 12 III. Search parameters for chemical substance groups and variants .. 15 1. Paracetamol .. 15 2. Hydrochlorothiazide .. 21 3. Ibuprofen .. 30 4. Omeprazole .. 33 5. Amlodipine .. 34 6. Simvastatin .. 37 7. Diclofenac .. 38 8. Ciprofloxacin .. 40 9. Pantoprazole .. 42 10. Lidocaine .. 43 11. Sodium Chloride .. 46 12. Fluconazole .. 52 13. Montelukast .. 53 14. Atorvastatin .. 54 15. Acetylsalicylic Acid .. 56 16. Amoxicillin .. 58 17. Donepezil .. 60 18. Ethinylestradiol .. 61 19. 66 20. Olanzapine .. 67 21. Clopidogrel .. 68 22. Risperidone .. 69 23. Tamsulosin .. 70 24. Aciclovir .. 71 25. Azithromycin .. 72 26. Levofloxacin .. 73 27. Finasteride.

5 74 28. Alendronic acid .. 75 29. Valsartan .. 77 30. Clarithromycin .. 77 31. Venlafaxine .. 79 32. Cetirizine .. 80 33. Sertraline .. 81 34. Ramipril .. 82 35. Calcium Carbonate .. 83 36. Sildenafil .. 85 37. Ascorbic Acid .. 85 Monitoring of medical literature and the entry of relevant information into the EudraVigilance database by the European Medicines agency EMA/517840/2015 Effective date: 1 April 2021 Page 3/386 38. Levetiracetam .. 87 39. 88 40. Terbinafine .. 90 41. Anastrozole .. 91 42. Citalopram .. 92 43. Ranitidine .. 93 44. Metformin .. 94 45. Lansoprazole .. 95 46. Fluoxetine .. 96 47. Tramadol .. 97 48. Letrozole .. 98 49. Escitalopram .. 99 50. Esomeprazole .. 100 51.

6 Bicalutamide .. 101 52. Gabapentin .. 102 53. Fentanyl .. 103 54. Quetiapine .. 104 55. Cefuroxime .. 105 56. Paroxetine .. 106 57. 106 58. Indapamide .. 108 59. Ondansetron .. 109 60. Candesartan .. 110 61. Risedronic Acid .. 111 62. Pravastatin .. 112 63. Glimepiride .. 114 64. Lisinopril .. 114 65. Carvedilol .. 115 66. 116 67. Latanoprost .. 117 68. Salicylic Acid .. 118 69. Metronidazole .. 120 70. Budesonide .. 121 71. Dexamethasone .. 122 72. Topiramate .. 124 73. Bisoprolol .. 124 74. Atenolol .. 125 75. Furosemide .. 126 76. Prednisolone .. 127 77. Irbesartan .. 129 78. Ambroxol .. 130 79. Lamotrigine .. 131 80. Mirtazapine .. 132 81. Ceftriaxone .. 132 Monitoring of medical literature and the entry of relevant information into the EudraVigilance database by the European Medicines agency EMA/517840/2015 Effective date: 1 April 2021 Page 4/386 82.

7 Acetylcysteine .. 133 83. Meloxicam .. 135 84. Ropinirole .. 136 85. Memantine .. 136 86. Loratidine .. 137 87. Zoledronic Acid .. 138 88. Zolpidem .. 139 89. Nebivolol .. 139 90. 140 91. Gemcitabine .. 142 92. Ibandronic Acid .. 142 93. Clindamycin .. 143 94. Betamethasone .. 144 95. Salbutamol .. 145 96. Naproxen .. 146 97. Desloratadine .. 147 98. Exemestane .. 148 99. Ketoprofen .. 149 100. Rivastigmine .. 150 101. Glyceryl Trinitrate .. 151 102. Piperacillin .. 152 103. Doxazosin .. 153 104. Estradiol .. 155 105. Metoprolol .. 156 106. Morphine .. 157 107. Isosorbide .. 158 108. Loperamide .. 159 109. Telmisartan .. 160 110. Glucose .. 161 111. Rabeprazole .. 163 112. Oxaliplatin .. 163 113.

8 Colecalciferol .. 164 114. Gliclazide .. 165 115. Lactulose .. 166 116. Pramipexole .. 167 117. Alprazolam .. 167 118. Diltiazem .. 168 119. Alfuzosin .. 169 120. Fluticasone Propionate .. 170 121. Formoterol .. 171 122. Levocitirizine .. 172 123. Betahistine .. 173 124. Dextromethorphan .. 174 125. Irinotecan .. 175 Monitoring of medical literature and the entry of relevant information into the EudraVigilance database by the European Medicines agency EMA/517840/2015 Effective date: 1 April 2021 Page 5/386 126. Ceftazidime .. 176 127. Lercanidipine .. 176 128. Paclitaxel .. 177 129. Xylometazoline .. 178 130. Epinephrine .. 179 131. Piroxicam .. 181 132. Potassium Chloride .. 181 133. Sumatriptan.

9 183 134. Perindopril .. 183 135. Doxycycline .. 184 136. Glucosamine .. 185 137. Itraconazole .. 186 138. Captopril .. 187 139. Codeine .. 188 140. Fluvastatin .. 189 141. Meropenem .. 189 142. Docetaxel .. 190 143. Allopurinol .. 190 144. Domperidone .. 191 145. Mometasone .. 192 146. Mycophenolic Acid .. 193 147. Amiodarone .. 193 148. Cyanocobalamin .. 194 149. Epirubicin .. 195 150. Galantamine .. 196 151. Valaciclovir .. 196 152. Celecoxib .. 197 153. Nifedipine .. 197 154. Vancomycin .. 198 155. Zolmitriptan .. 199 156. Moxifloxacin .. 199 157. Diazepam .. 200 158. Erythromycin .. 201 159. Folinic Acid .. 202 160. 203 161. Carbidopa .. 204 162. Cromoglicic Acid .. 205 163. Heparin .. 206 164.

10 Oxygen .. 207 165. Zinc Oxide .. 207 166. Ketoconazole .. 209 167. Ofloxacin .. 209 168. Folic Acid .. 210 169. Progesterone .. 212 Monitoring of medical literature and the entry of relevant information into the EudraVigilance database by the European Medicines agency EMA/517840/2015 Effective date: 1 April 2021 Page 6/386 170. Sodium Hydrogen Carbonate .. 213 171. Triamcinolone .. 214 172. 215 173. Cefotaxime .. 216 174. Gentamicin .. 217 175. 217 176. Granisetron .. 218 177. Pioglitazone .. 219 178. Amisulpride .. 219 179. Clotrimazole .. 220 180. Remifentanil .. 221 181. Spironolactone .. 221 182. Tacrolimus .. 222 183. Dorzolamide .. 223 184. Rosuvastatin .. 223 185. Midazolam.