がんのリスクの大きさ＜何倍程度 ... - ncc.go.jp

1 40 ( )(Preston DL, et al. Radiation Research 2007;168:1 64) 18 10 15 (ZablostskaLB, et al. Br J Cancer 2011;104:181-7) (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 69, 1997) 40 69 10 15 1 JPHC Study - 18 10- 15 10 C 36 10 1000mSv 300g / ( ) 1000mSv ( ) 450g / ( )150-290mSv < > BMI>30 ( ) 2,3,7,8-TCDD ( ) 300-449g/ ( )

2 50-140mSv < > ( ) BMI 30 ( ) BMI 19 ( ) ( ) ( ) ( ) ( ) < > ( ) 100mSv 2,3,7,8-TCDD ( ) Prev Med. 2004;38:516-522. ( 450+ / ( ) 450g Br J Cancer. 2005;92:182-187. 300-449 / ( ) 300-449 g Br J Cancer. 2005;92:182-187. BMI 30 ( ) BMI Causes Control. 2004;15:671-680. BMI 19 ( ) BMI Causes Control. 2004;15:671-680. ( ) (1 METs , ) (1 METs , )Am J Epidemiol. 2008;168:391-403. ( ) ( : = 43g/day, = g/day) ( : = , = g/day)Am J Clin Nutr. 2010;9:456-464. ( ) ( = 1 110g) ( = 1 420g)Am J Epidemiol. 2008;167:59-70. ( ) Int J Cancer. 2008;122:653-657. C 36 C Cancer Lett.)

3 2011;300:173-179. 10 H + CagA+H - CagA-Cancer Epidemiol Biomarkers ;15:1341-1347. Int J Cancer. 2002;99:245-251. 300+ / 300g Cancer Lett. 2009;275:240-246. Br J Cancer. 2004;90:128-134. (1 METs ) (1 METs )Cancer Causes Control. 2007;18:199-209. BMI>30 BMI 30 BMI Causes Control. 2005;16:839-850. BMI>30 BMI 30 BMI <19 Ann Epidemiol. 2007;17:304-312. Int J Cancer. 2008;122:653-657. JPHC 23 1 ( 180ml) 1 ( 633ml) 25 120ml 2 ( 200ml) 1 (60ml )