Ordered Item DESC Primary Antibiotic Secondary Antibiotic

1 Revised 10/25/2019. Ordered Item DESC Primary Antibiotic Secondary Antibiotic Abdominal aortic Aneurysm By/Endo Stent Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Abdominal aortic Aneurysm Bypass Graft Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Abdominal Biopsy Ask Proceduralist if Necessary Abdominal Exploration/Revision Cefazolin + Flagyl Clindamycin + Aztreonam Abdominal Fistula Tractotomy Cefazolin + Flagyl Clindamycin + Aztreonam Abdominal Fistula Tractotomy Lap Cefazolin + Flagyl Clindamycin + Aztreonam Abdominal I&D Cefazolin + Flagyl Clindamycin + Aztreonam Abdominal I&D w/Wound Vac Cefazolin + Flagyl Clindamycin + Aztreonam Abdominal Mass/Soft Tissue Excision Ask Proceduralist if Necessary Abdominal Mesh Removal Cefazolin + Flagyl Vancomycin + Aztreonam Abdominal Perineal Resection Cefazolin + Flagyl Vancomycin + Aztreonam Abdominal Wall Reconstruction Cefazolin + Flagyl Clindamycin + Aztreonam Abdominal

2 Wall Resection Cefazolin Vancomycin Abdominoplasty Cefazolin Vancomycin Abdominosacrocolpopexy Abdominal Cefazolin, Add Gent for prosthetic material Clindamycin + Gentamicin ACE Procedure Ask Proceduralist if Necessary Acetabulum Radical Resection Ask Proceduralist if Necessary Achilles Tendon Debridement Ask Proceduralist if Necessary Achilles Tendon Lengthening Ask Proceduralist if Necessary Achilles Tendon Repair Ask Proceduralist if Necessary Achilles Tenotomy Percutaneous Ask Proceduralist if Necessary Acid Reflux Study/24hr pH None Indicated None Indicated ACL Reconstruction Arthroscopic Ask Proceduralist if Necessary ACL Repair Ask Proceduralist if Necessary Acoustic Neuroma Resection Cefazolin, Add Vanc for MRSA Risk Vancomycin Acrochordon Excision Cefazolin, Add Vanc for MRSA Risk Vancomycin Acrominoplasty/Distal Clavicle Repair Ask Proceduralist if Necessary Adenoidectomy Ask Proceduralist if Necessary Adenoidectomy/Myringotomy w/Tubes Ask Proceduralist if Necessary Adjacent Tissue Transfer Ask Proceduralist if Necessary Adrenalectomy Cefazolin Vancomycin AICD Laser Lead Extraction Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam ALT Free Flap Cefazolin Vancomycin + Gent (if eGFR>50)

3 Or Aztreonam Alveoloplasty Cefazolin Clindamycin Amputation Ray/Syne/Transmetatarsal None Indicated None Indicated Anal Biopsy Ask Proceduralist if Necessary Anal Dilation/Stent Ask Proceduralist if Necessary Anal Sphincterotomy Ask Proceduralist if Necessary Anes Procedure Ask Proceduralist if Necessary Angioplasty Ask Proceduralist if Necessary Ankle Arthroscopy None Indicated None Indicated Ankle Biopsy Saucerization Ask Proceduralist if Necessary Ankle External Fixation Application Cefazolin, Add Vanc for MRSA Risk Vancomycin Ankle Fusion Ask Proceduralist if Necessary Ankle Fusion Endoscopic Ask Proceduralist if Necessary Ankle Fusion Subtalar Ask Proceduralist if Necessary Ankle Hardware Removal Ask Proceduralist if Necessary Ankle Lateral Ligament Repair Ask Proceduralist if Necessary Ankle Loose Body Removal Ask Proceduralist if Necessary Ankle ORIF Cefazolin, Add Vanc for MRSA Risk Vancomycin Ankle Saucerization Ask Proceduralist if Necessary Ankle Tendon Transfer Ask Proceduralist if Necessary Ankle Total Replacement Cefazolin.

4 Add Vanc for MRSA Risk Vancomycin Ankle Triple Arthrodesis Ask Proceduralist if Necessary Ankle/Foot OCD Drilling Ask Proceduralist if Necessary Anomalous Coronary Artery Repair Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Anoplasty Ask Proceduralist if Necessary Anoscopy None Indicated None Indicated Anterior Chamber Washout None Indicated None Indicated Anterior Segment Wound Revision None Indicated None Indicated Anterior Skull Base Resection Cefazolin, Add Vanc for MRSA Risk Vancomycin Aorta Coarctation Excision Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Aorta/Fem/Pop Bypass Graft Cefazolin Vancomycin Aorta/Iliac/Fem/Pop Thrombectomy Cefazolin Vancomycin.

5 Add Gent if abdominal aorta or groin incision aortic Aneurysm Repair Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam aortic Arch Replacement Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam aortic Endarterectomy Cefazolin Vancomycin aortic Endo Stent Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Aorto Femoral Bypass Graft Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Aortogram/Arteriogram Ask Proceduralist if Necessary Aorto iliac Bypass Graft Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Aortovisceral Debranching Bypass Graft Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Appendectomy Cefazolin + Flagyl Clindamycin + Aztreonam Application Bilaminate Skin Substitute Cefazolin Vancomycin Aqueous Shunt Implantation None Indicated None Indicated Aqueous Shunt Revision None Indicated None Indicated Arm Amputation Cefazolin Vancomycin Arm Amputation/Disarticulation Cefazolin Vancomycin Arm Mass Excision None Indicated None Indicated Arm ORIF Cefazolin, Add Vanc for MRSA Risk Vancomycin Arm Soft Tissue Resection None Indicated None Indicated Artifical Urinary Sphincter Removal Cefazolin Vancomycin Artificial Urinary Sphincter Insertion Vancomycin + Gentamicin Ask Proceduralist ascending Aneurysm Repair/Ross Procedure Cefuroxime.

6 Add Vanc if MRSA Risk Clindamycin or Vancomycin Aspiration Abscess/Hematoma/Cyst None Indicated None Indicated Atrial Ablation Ask Proceduralist if Necessary Atrial Ablation Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Atrial Myxoma Excision Robotic Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Atrial Myxoma Resection Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Atrial Septal Defect Repair Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Revised 10/25/2019. Atrial Septal Defect Repair Robotic Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam AV Fistula Lower Extremity Cefazolin Vancomycin.

7 Add Gent if abdominal aorta or groin incision AV Fistula Upper Extremity Not Indicated Not Indicated AVR Cefuroxime, Add Vanc if MRSA Risk Vancomycin + Gent (if eGFR>50) or Aztreonam Axilla Hidradentitis Excision Cefazolin Vancomycin Axillary Aneurysm Repair Cefazolin Vancomycin Axillary Dissection Cefazolin Vancomycin Axillary Lymph Node Biopsy None Indicated None Indicated Axillary Axillary Bypass Graft Cefazolin Vancomycin Axillary Brachial Bypass Graft Cefazolin Vancomycin Axillary Femoral Bypass Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Axillary Popliteal Bypass Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Axillo Bifemoral Bypass Cefazolin Vancomycin. Add Gent if abdominal aorta or groin incision Back I&D Cefazolin Vancomycin Back Mass/Soft Tissue Excision Ask Proceduralist if Necessary Back/Flank/Radical Excision Soft Tissue Mass None Indicated None Indicated BAHA Ear Implant None Indicated None Indicated Barium Swallow Modified None Indicated None Indicated Bartholin Gland I&D None Indicated None Indicated Bartholin's Cyst Marsupialization None Indicated None Indicated Bartholin's Gland or Cyst Excision None Indicated None Indicated Basilic Vein Transposition Cefazolin Vancomycin Biceps Repair Distal Open None Indicated None Indicated Biceps Tendon Repair None Indicated None Indicated Biceps Tenotomy None Indicated None Indicated Bile Duct Reconstruction Cefazolin

8 + Flagyl Vancomycin + Aztreonam Bile Duct Resection Cefazolin + Flagyl Vancomycin + Aztreonam Bile Duct Tumor Excision Cefazolin + Flagyl Vancomycin + Aztreonam Biliary Exploration Cefazolin + Flagyl Vancomycin + Aztreonam Bladder Augmentation Cefazolin Clindamycin + Gentamicin Bladder Diverticulum Excision Cefazolin Clindamycin + Gentamicin Bladder Neck Closure Cefazolin Clindamycin + Gentamicin Blepharoplasty Cefazolin Vancomycin Blepharoptosis Rpr LevatorResectExtApp Cefazolin (+ Vanc for Implants) Clindamycin Block Celiac Plexus None Indicated None Indicated Block Lumbar Facet None Indicated None Indicated Block Lumbar Sympathetic None Indicated None Indicated Block Nerve Root None Indicated None Indicated Block Stellate Ganglion None Indicated None Indicated Blood Patch None Indicated None Indicated Boari Flap Cefazolin, Add Gent for prosthetic material Clindamycin + Gentamicin Body Lift Lower None Indicated None Indicated Bone Anchored Hearing Aid Insertion Cefazolin (+ Vanc for Implants)

9 Vancomycin Bone Anchored Hearing Aid Removal None Indicated None Indicated Bone Biopsy Open None Indicated None Indicated Bone Biopsy Radius/ulna/hand None Indicated None Indicated Bone Biopsy Trocar or Needle None Indicated None Indicated Bone Marrow Harvest Ask Proceduralist if Necessary Bone Spur Excision None Indicated None Indicated Botox Injection None Indicated None Indicated Brachial Artery Repair Cefazolin Vancomycin Brachial Carotid Bypass Cefazolin Vancomycin Brachial Plexus Block None Indicated None Indicated Brachial Plexus Neuroplasty Cefazolin, Add Vanc for MRSA Risk Vancomycin Brachial Brachial Bypass Graft Cefazolin Vancomycin Brachioplasty Cefazolin Vancomycin Brachytherapy HDR Cefazolin, Add Gent for prosthetic material Clindamycin + Gentamicin Brain Biopsy Craniotomy Cefazolin, Add Vanc for MRSA Risk Vancomycin Brain Endoscopy Cefazolin.

10 Add Vanc for MRSA Risk Vancomycin Branchial Cleft Cyst Excision OTO Cefazolin Clindamycin Breast Augmentation Cefazolin Vancomycin Breast Biopsy None Indicated None Indicated Breast Biopsy Dye/Wire None Indicated None Indicated Breast Biopsy/Sentinel Node Biopsy Cefazolin Vancomycin Breast Capsulotomy Cefazolin Vancomycin Breast Capsulotomy w/Implant Exchange Cefazolin Vancomycin Breast I&D Ask Proceduralist if Necessary Breast I&D w/Flap Closure Ask Proceduralist if Necessary Breast Implant Exchange Cefazolin Vancomycin Breast Implant Insertion Cefazolin Vancomycin Breast Implant Removal Cefazolin Vancomycin Breast Intraoperative Radiation Therapy Cefazolin Vancomycin Breast Lumpectomy Cefazolin Vancomycin Breast Lumpectomy w/Sentinel Node Biopsy Cefazolin Vancomycin Breast Neurofibroma Excision Cefazolin Vancomycin Breast Nipple Exploration Cefazolin Vancomycin Breast Periprosthetic Capsulectomy Cefazolin Vancomycin Breast Recon Latissimus Free Flap Cefazolin Vancomycin Breast Recons w/Expander/Implant Cefazolin Vancomycin Breast Reconstruction Latissimus Flap Cefazolin Vancomycin Breast Reconstruction Revision Cefazolin Vancomycin Breast Reduction Cefazolin Vancomycin Bronch w/Dilation w/woFluoro None Indicated None Indicated Bronch w/EM Navigation/Superdimension None Indicated None Indicated Bronch w/Excis Tumor w/wo Fluoro None Indicated None Indicated Bronchial/Tracheal Stent Placement None Indicated None Indicated