Overview of SNP Genotyping - National Institute of ...
Differential survival • Population stratification • Null allele – Technical – Technical • Allele dropout • Nonspecific assays Duplicated regions: HWE Example : Small et al, NEJM 2002 v347 p1135 : Frequency Analysis : tagSNP Allele Frequency : 0% 20% 40% 60% 80% 100% 0% 20% 40% 60% 80% 100%: PGA IGAP : European African : tagSNP ...
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