Pathways of Parkinson’s Disease - Abcam

1 Genetic MutationDJ-1a-synucleina-synucleinPINK-1 LRRK2 UHCL1 SAT1(Dorfin)(SIAH)N Ring 2 Ring 1 CIBR(Parkin)Tyr143O-linkedUBLP arkinFBXO7mitochondrialdysfunctionmisfol dedproteinglycosylationProtofibrilsfibri lsCa2+p25 Cdk5 CAKp35c-AblCdk5 UbUbUbUbUbUbDeath stimuliCalpainsCdk5-p25aSP16 PBeclin 1 Cdk5 - CK1p53E1 ATPAmp+PPiUbUbUbch8 E2 Ubch7mitochondrialDNA polymorphismsDJ-1aggregationUPSsubstrate sUbUbUbUbUbUbUbUbUbUbUbUbUbdegradedprote inLewy bodyDorfinDopamineoxidationDADADA tubulinsp38 Synphilin-1cdcrel-1 Cyclin ECHIPSkp1 Synaptotagmin MEF2 of parkinson s DiseaseRelated antibodies and proteinsfrom Abcam :See more products at.

2 ApplicationsHostSpeciesDatasheetReactivi ty antibodiesalpha Synuclein (phospho Y125) antibodyP-Rb-10789 Beclin 1 antibody [EPR1733Y]M ICC/IF, IHC-P, IP, WBRbHu51031c Abl antibodyP ICC/IF, WBRbHu85947 Calpain 1 antibody - Domain IP ICC/IF, WBRbHu, Ms, Rat28258 Cdk5 antibody [2G2]M ELISA, IP, WBMsHu, Ms, Rat28441 Cyclin E antibodyP WBRbHu, Ms88259 Dopamine antibodyP ELISA, ICC, ICC/IFRb-6427 DORFIN antibodyP-Rb-10889 FBXO7 antibodyP WBRbHu84129 LRRK2 antibodyP ELISA, WBRbHu, Ms38003 NMDAR1 antibody - Neuronal MarkerP ICC/IF, IHC (PFA fixed), WBRbRat17345 NMDAR2B (phospho S1480) antibodyP IHC-FoFr, WBRbMs, Rat18533 NMDAR2C antibody [G218B5]M WBMsRat78133p35 antibodyP ELISA, ICC/IF, WBRbHu, Ms, Rat64960p38 (phospho T180 + Y182) antibodyP ICC/IF, WBRbHu38238p53 (acetyl K382)

3 AntibodyP WBRbHu3731 PACRG antibodyP WBRbHu4090 Parkin antibodyP WBRbHu, antibody - Neuronal MarkerP ICC/IF, IHC-Fr, IHC-P, WBRbHu, Ms, antibody [13C4 / I3C4]M ICC, ICC/IF, IHC-FoFr, IHC-Fr, MsHu, Ms, Rat, Dog,8189- Neuronal MarkerIHC-P, WBGpig, Pig, Rb, ShpPINK1 antibodyP ICC/IF, IHC-FoFr, IHC-P, WBRbHu, Ms, Rat65232 SEPT5 antibody [SP18]M WBMsHu, Ms, Rat69538 Skp1 antibody [EPR3303]M Flow Cyt, IHC-P, WBRbHu, Ms, Rat80586 STUB1 antibodyP ICC/IF, WBRbHu, Ms39559 Synphilin 1 antibodyP IHC-Fr, IHC-P, WBRbHu, Ms, Rat6179 Ube2L3 antibodyM ICC/IF, WBMsHu58262 Ube2L6 antibody - N-terminalP ELISA, IHC-P, WBRbHu71800 Ubiquitin antibodyP ELISA, ICC/IF, IF, IHC-FoFr,RbHu, Chk, Cow,8134 IHC-Fr, HC-P, IP, WBDmUCHL1+3 antibodyP WBRbHu, Ms, Rat75275alpha Synuclein proteinSDS-PAGEE.

4 ColiHu51189c Abl protein (Active)FuncS, SDS-PAGESf9 Hu69810 Calpain 1 protein (Active)FuncS, SDS-PAGEE rythrocytes Hu91019 Cdk5 protein (Tagged)FuncS, SDS-PAGEE. coliHu56282 NMDAR1 peptideBLCHORat17568p38 protein (Active)FuncS, SDS-PAGESf9Hu60710p53 protein (Tagged)FuncSE. coliHu43615 PARK7/DJ1 protein (His tag)SDS-PAGEE. proteinELISA, Inhib, WBE. coliHu75957 SEPT5 protein (Tagged-His Tag)MS, SDS-PAGEE. coliHu91710 Skp1 proteinSDS-PAGEE. coliHu90687 STUB1 proteinSDS-PAGEE. coliHu82791 Ube2L3 proteinSDS-PAGEE. coliHu73540 Ube2L6 proteinSDS-PAGEE. coliHu80713 Ubiquitin protein (His tag)Conjugation, SDS-PAGEE.

5 ColiHu81662 Proteins/PeptidesApplicationsExpression E antibody [HE12] (ab3927)Clonality ApplicationsHostSpecies cross reactivityMFlow Cyt, ICC/IF, IHC-Fr,MsHuIHC-P, WBNMDAR2A (phospho Y1325) antibody (ab16646)Clonality ApplicationsHostSpecies cross reactivityPIHC-FoFr, IHC-P, WBRbMs, Ratp38 antibody (ab7952)Clonality ApplicationsHostSpecies cross reactivityPICC, ICC/IF, IHC-Fr,RbHu, Ms, RatIHC-P, IP, WBPARK7/DJ1 antibody (ab18257)Clonality ApplicationsHostSpecies cross reactivityPICC/IF, IHC-P, WBRbHu, Ms, RatTubulin antibody [YOL1/34] - Microtubule Marker (ab6161)Clonality ApplicationsHostSpecies cross reactivityMELISA, ICC/IF, IHC-FoFr, RtHu, Ms, Rat, Allg, Dog, RIA, WBSc, S pom