Pfizer in South Africa

1 Pfizer in South Africa Pfizer South Africa was first established in South Africa (SA) in 1953 and with its vision of living our full potential in striving for a healthier Southern Africa , embraces its dream of being able to see every Southern African having access to quality healthcare. Pfizer SA s head office is in Sandton and is made up of three business units: Pfizer Innovative Health, Pfizer Established Health, and Pfizer Consumer Health. WORKFORCE CONTRIBUTION* CLINICAL TRIALS*. Nine therapeutic/disease areas are being studied 21b including: 314a Trials Pfizer Employees in South Africa 75b Trial Centres 1,878b Participants Cardiovascular Metabolic Disease Gastroenterology Oncology Hematology Biosimilars: Oncology &. Infectious Diseases Inflammation Inflammation Vaccines Pfizer South Africa - Key Facts and Figures 100 Diversification 2. Prescription Products Global Healthcare Portfolio Strategic Partnerships Pfizer makes over 100 different prescription Pfizer 's diversified global healthcare portfolio has a broad offering, Pfizer invests considerable resources in products available and imparts product and disease including medicines for cardiovascular, neuroscience, women s health, partnerships and external research knowledge to over 4,000 healthcare professionals urology, anti-infectives, oncology, biological, anti-inflammatory and efforts with small biotech companies throughout South Africa as well as 4 other African pain, anti-coagulation, ophthalmology, vaccines and consumer and universities in South Africa .

2 1. countries. health. Key Investments and Collaborations Antifungal Partnership Programme Memberships Since 2000, Pfizer has been in partnership with the South Notwithstanding our mission to become the premier, innovative biopharmaceutical company, we still find value in African Department of Health by donating working with competitor companies through industry associations around common goals, such as engaging treatments for two opportunistic fungal infections government in creating an enabling regulatory environment to conduct our business. In this regard, Pfizer is a associated with HIV and AIDS (cryptococcal meningitis member of Innovative Pharmaceutical Association South Africa (IPASA). We are also a member of the and esophageal candidiasis). To date, the programme American Chamber of Commerce in South Africa (AMCHAM) and the Self-Medication Manufacturers Association expanded globally and donated more than $ billion in of South Africa (SMASA).

3 Medicine, helping people in 63 countries hardest hit by Pfizer s Key Stakeholders HIV/AIDS. Sixteen years into the program,me South Africa Healthcare professionals, patients, pharmacy groups, hospital groups, patient-advocacy groups, government, has 1,264 sites, accounting for almost 50% of all the sites globally. organised business platforms and the media. Pfizer continues to work closely with government on key issues impacting the innovative pharmaceutical industry in South Africa and with three key government departments in particular: Department of Health (DoH); Department of Science & Investing in South Africa 's Future Technology (DST) and the Department of Trade & Industry (dti). The Biovac Technology Transfer initiative is a public-private partnership between the South African Making a Difference government and the Biovac Institute, to locally The Nelson Mandela Children s Hospital (NMCH) is a project initiated by the Nelson Mandela Children s Fund in manufacture a pneumococcal vaccine which is very important in preventing many pneumonia-related 1995.

4 Before his passing, Nelson Mandela shared his dream of building a hospital that offers children of Southern Africa , state-of-the-art healthcare. The Hospital Trust was established and tasked with raising R1 billion to bring the hospital to life. deaths, particularly in children up to the age of 5. Construction began on 22 April 2014, and the hospital opened its doors on 02 December 2016. Launched in 2015, the project entails skills and technology transfer by Pfizer to the Biovac Institute to The hospital is a 200-bed specialised paediatric hospital located in Johannesburg. NMCH will provide paediatric healthcare provide it with the capability to manufacture the services to children up to the age of 16. The hospital is a quaternary hospital which caters for the needs of extremely sick vaccine by 2019. children with complicated illnesses that require highly specialised care. To date, Pfizer has donated R3 million towards the construction of the hospital and for the purchase of two Ultrasound Imaging Units, to be mainly used for the detection of Working With Others to Do Good cardiothoracic defects in babies and children.

5 The Public Health Enhancement Fund Unjani Clinics is a sustainable full-service Primary Healthcare (PHC) facility which empowers entrepreneurs to transition (PHEF) is a consortium of over 20 private healthcare from salaried health care workers to a full business ownership model. Unjani Clinics provide affordable PHC to under-served companies that have partnered with government to communities in South Africa . The clinics are staffed with a dispensing nurse (who is able to dispense medicines up to support the implementation of priority healthcare schedule 4) and a clinic assistant. The fee-based service model enables employment, business sustainability and the programs. They pool funds to be used for the benefit of empowerment of black women to be professional nurses through the use of a business model, based on franchise principles. transformative healthcare projects, jointly agreed to Pfizer has sponsored a clinic in Hammanskraal and provided further funding for the procurement of 28 basic Mindray DP10 with the Minister of Health, Dr.

6 Aaron Motsoaledi. Ultrasonic Diagnostic Imaging Systems, printers, trolleys and certified training for 28 clinics in the network. The following projects were jointly agreed to and are in various stages of implementation and success: Global Health Innovation Grants (GHIG), a Pfizer Foundation* programme, partners with nonprofits and social enterprises in the developing world to support innovative health products and services for underserved Expansion of healthcare professionals populations. This programme helps to extend health impact and foster local innovation at the country level. The set-up of a mobile clinic by Sevamob, for migrant communities in Johannesburg. These clinics aim to Academy for leadership and management increase access to doctors, reduce anemia and dental issues and increase HIV awareness. in healthcare Support for the training of Masters and PhD students for Pfizer Foundation is also partnered with PATH to support their Global Health Innovation Accelerator, an combating and developing new interventions in HIV, initiative that is building the capacity of local innovators to develop, manufacture, and deploy global health technologies AIDS, and TB.

7 For vulnerable groups such as nurse- led telephone triage services to improve newborn health and ARV dispensing kiosks. Updated July 2017 a. Pfizer South Africa , July, 2017. b. Pfizer data on file, Development Operations as of July 18, 2017. Randomised Patients: not all randomised patients may be enrolled in clinical trials. *The Pfizer Foundation is a charitable organisation established by Pfizer , Inc. It 2. is a separate legal entity from Pfizer , Inc. with distinct legal restrictions.