基因工程鼠目录 - pku.edu.cn

1 ( 1 Chiken -actin-eGFP 2 Chiken -actin-Luc 3 (PDGF-eGFP)4 Chiken -actin-R FP 5 Thy-1 (Thy-1-YFP)6 Cre (CaMK2-Cre)7 Cre GFPA-Cre 8 Nestin Cre Nestin-Cre 9 Cre UBC-cre/ESR110 Cre Lck-cre11 MX1-Cre 12 Cre Carp-cre13 (Cg)-Gt(ROSA)26 Sortm4(ACTB-tdTomato,-EGFP)Luo/J14 Cre Lyz2-Cre15 LysM-EGFP16 17 18 19 Cre (Dbx1-iCre)20 FLP (MHC-FLP 21 FLP (CMV-FLP 22 FLP (SPC-FLP 23 Cre (MHC-Cre 24 Cre (SPC-Cre 25 FLP CBA-FLP 26 LRG5 Cre (cre/ERT2)Cle/J 27 Cre Myh6-cre/Esr1 28 cre 29 Cre Ipf1-cre 30 CAG-DsRed-1 31 Taglntm2(cre) 32 Nes-cre (SJL)-Tg(Nes-cre)1 Kln/J 33 ACTA1-cre 34 Cdh5-cre 35 CDX2-cre 36 Ckmm-cre 37 Itgax-cre 38 Cd8a-cre 39 Cre Gt(ROSA)26 Sortm1 Sor 40 Foxp3-EGFP/cre 41 Lck-cre 42 Lyz2tm1(cre) 43 Tagln-cre 44 R26-rtTA Col1a14F2A 45 Gt(ROSA)26 Sor FLP 46 (Cg)-Gt(ROSA)26 Sortm4(ACTB-tdTomato,-EGFP)Luo/J 47 CRE (Myh6-cre)))))))

2 48 SD chicken -actin-EGFP 49 SD chicken -actin-RFP 1 ApoE2 CMV-ApoE2 2 ApoE3 CMV-ApoE3 3 A poE 4 CMV-ApoE4 4 24- CMV-Dhcr24 5 ApoE3 ApoE-KO X CMV-hApoE3 6 ApoE4 ApoE-KO X CMV-hApoE47 ApoE2 ApoE-KO X CMV-hApoE2 8 PRKAA2 AMPK- -2 AMPKP- -2 knock-out 9 ApoE ApoE knock-out 10 LDLR-KO 11 CMV-Visfatin 12 (Lepob or ob/ob)13 II DB/DB 14 I NOR/LtJ 15 II (BKS)-Cpefat/J 16 KK 17 visfatin 18 FOXP3 19 IGF11 20 IGF1 21 OB/OB (CMV-Visfatin-OB/OB 22 CYP2C19 (CMV-h-CYP2C19)23 RA1V9 (SS-Tg(RA1V9)64 Opaz)24 ApoC3-CETP SS-Tg(ApoC3-CETP)53 Opaz25 ApoA1 (Dahl SS/Jr-Tg[hApoA1]116))

3 26 Brs3 27 Pparg 28 Ttpa 29 Ucp2 30 PPARA CMV-h-PPARA 1 DKK3 CMV-m-Dkk3 2 HB-EGF CMV-HB-EGF 3 MKP-1 CMV-hMKP-1 4 XAGE3 CMV-hXAGE3 5 AMPKP1 Fe56 AMPKP1 knock-out 6 Jak3 Janus kinase3 knock-out 7 JNK-1 JNK-1 knock-out 8 JNK-2 JNK-2 knock-out 9 JNK-3 JNK-3 knock-out 10 P21 CDKN1A p21 knock-out 11 Taz wwtr1 Taz knock-out 12 MAPK14 p38 MAPK14 knock-out 13 p53 p53 knock-out 14 KIAA0174 U6-KIAA0174 knock-down 15 PTPA PPP2R4 PTPA knock-out 16 ATM ATM knock-out 17 Gata4 18 Mapk8 19 Mapk9 1 Gfi1 Floxed Gfi1 2 Gfi1 Gfi1 knock-out 3 Rag2 Rag2 knock-out 4 TNF- TN F- knock -out 5 Trim32 Trim32 knock-out 6 gfi1 Vav-gfi1 7 Wip-1 PPM1D Wip-1 knock-out 8 HBV 9 hMan2c1 CMV-hMan2c1 10 Ace2 human Ace2 11 Man2c1 U6-hMan2c1 knock-down 12 Gfi1-eGFP Knock-in 13 CD24 CD24 knock-out 14 2- ( H2K-hB2M )15 3 CXCR3 KO 16 Ptprc Pep3 Ptprca Pepcb 17 IFN- 18 L-33 CMV-IL-33 19 -gamma IFN-gamma KO 20 IgM Igh-6 KO 21 MRL/MpJ 22 Thy1a 23 Rag-1 Rag1-KO 24 Icosl 25 IL2 - 26 Csf3 27 HLA-A 28 T 29 B1 ephrin B1 30 MHC class Ii 31 T 32 HCV CD81 (pUBC-CD81)33 HCV CLDN1 (pUBC-CLDN1)34 HCV OCLN (pUBC-OCLN)35 HCV SCARB1 (pUBC- SCARB1)

4 36 Csf2rb2 Csf2rb 37 IRF-7 38 myd88 39 Rag1 40 Sele Sell 41 Tcra-V2 Tcrb-V5 OT-1 42 Tcrb Tcrd Tcrdtm1 Mom/J 43 Tumor necrosis factor (ligand) superfamily, member 4 44 T 45 Faslpr MRL/MpJ-Faslpr/J 46 Toll-like receptor 3 Tlr3 B6;129S1-Tlr3tm1 Flv/J 47 CD47 antigen 48 Interferon regulatory factor 9 microRNA 1 microRNA181a miRNA181a-Tg 2 microRNA222 miRNA222-Tg 3 microRNA 29c ( miRNA 29c-Tg)4 microRNA195 miRNA195-Tg 5 microRNA106b miRNA106b-Tg 6 microRNA34a miRNA34a-Tg 1 Hela (Hela-DsRed)2 HepG2 (HepG2-eGFP)3 H460 H460-eGFP 4 Hepa1-6 Hepa1-6-eGFP 5 Hepa1-6 Hepa1-6-DsRed 6 BTT BTT739-eGFP 7 H460 H460-DsRed 8 A549 A549-eGFP 9 CAC02 CACO2-DsRed 10 Her2 MMTV-ErbB2 11 p53 BALB/C p53 knock out 12 HCT116 (HCT116-DsRed)

5 13 HCT116 (HCT116-eGFP)14 HCT-8 (HCT-8-eGFP)15 SW1990 SW1990-DsRed 16 SW1990 SW1990-eGFP 17 EC9706 EC9706-DsRed 18 EC9706 EC9706-eGFP 19 NCI-H1299 (NCI-H1299-eGFP)20 Capan-2 Capan-2-DsRed 21 Hela (Hela-eGFP)22 CRE 23 Separase Separase-Ko 24 4T1 4T1-LUC 25 A549 (A549-DsRed)26 BEL-7402 (BEL-7402-eGFP)27 BEL-7402 (BEL-7402-LUC)28 BGC823 (BGC823-eGFP)29 BGC823 (BGC823-LUC)30 capan-2 31 HEPA1-6 (HEPA1-6-LUC)32 KYSE150 (KYSE150-LUC)33 LA795 (LA795-eGFP)34 LEWIS (LEWIS-eGFP)35 LEWIS (LEWIS-DsRed)36 MGC803 (MGC803-eGFP)37 OVCAR-3 (OVCAR-3-eGFP)38 SMMC-7721 (SMMC-7721-eGFP)39 SMMC-7721 (SMMC-7721-LUC)40 SMMC-7721 (SMMC-7721-DsRed)41 MGC803 (MGC803-LUC)T739 42 BRCA1 (pUbc-m-BRCA1 43 Pten 44 Kras 45 P53 B6.)

6 129S4-Trp53tm5 Tyj/J 46 P53 129 129-Trp53tm1 Tyj/J 47 4T1 (4T1-eGFP)48 4T1 (4T1-DsRed)49 4TO7 (4TO7-LUC)50 B16 (B16-LUC)51 66C14 (66C14-LUC)52 HCT-116 HCT-116-LUC 53 PANC-1 (PANC-1-DsRed)54 SHSY5Y (SHSY5Y-LUC)55 SW1990 (SW1990-LUC)56 KYSE510 (KYSE510-eGFP)57 LEWIS LEWIS-LUC 58 PANC-1 (PANC-1-eGFP)59 P53 1 1 DKK3 Dkk3-ko 2 ApoB100 ApoB-Ko3 Nos3 4 5 HB-EGF 6 PDGF 7 PDGFb 1 AVP (PDGF-h-AVP 2 4 3 CALCB (CBC-CALCB 4 (AGT-KO)5 A 6 D1a 7 D2 8 ApoA1 pUbc-h-ApoA1 9 ApoC3 pUbc-h-ApoC3 10 KLK1 (CBC- h-KLK1 11 CALCA (CBC-CALCA 12 GRK4 (CBC-GRK4 13 GRK4 A142V (CBC-GRK4 A142V 14 GRK4 P65L (CBC-GRK4 P65L 15 GRK4 A486V (CBC-GRK4A486V 16 KNG1 (CBC-KNG1 17 KCNQ1V180L (MHC-h-KCNQ1V180L 1 ( (CAT)4033 Wcl/Mmmh)2 Foxo3 (FVB.)))))))))))

7 3 ATM ATM-KO 1 IL21 (CMV-MIR-IL21)2 IL1A (CMV-MIR-IL1A)3 IL1 (CMV-MIR-IL1 )4 IL2 (CMV-MIR-IL2)5 IL3 (CMV-MIR-IL3)6 IL4V2 (CMV-MIR-IL4V2)7 IL5 (CMV-MIR-IL5)8 IL-8 (CMV-MIR-IL8)9 IL9 (CMV-MIR-IL9)10 IL10 (CMV-MIR-IL10)11 IL11 12 IL12A CMV-MIR-IL12A 13 IL15V1 14 IL16V1 (CMV-MIR-IL16V1)15 IL17A (CMV-MIR-IL17A)16 IL17C (CMV-MIR-IL17C)17 IL18 (CMV-MIR-I18 IL19V2 (CMV-MIR-IL19V2)19 IL20 (CMV-MIR-IL20)20 EBI3 (CMV-MIR-EBI3)21 IL22 (CMV-MIR-IL22)22 IL33 CMV-MIR-IL33, EBI3 and P27 subunites)23 IL23A (CMV-MIR-IL23A)24 IL24V1 (CMV-MIR-IL24V1)25 IL25 (CMV-MIR-IL25)26 IL26 (CMV-MIR-IL26)27 IL27 (CMV-MIR-IL27)28 IL32 (CMV-MIR-IL32) (CMV-Keratin4E609K) 1 ASPP2 ASPP2-KO 2 caveolin-1 Cav1-KO 3 SJL/J 4 IAE IAE-KO 5 WB/ReJ KitW/J 6 Kit KitW-v 7 EXO1 EXO1- KO 8 RUNX3 RUNX3- KO 9 Tg(TERT)10 RNA Terc-KO 11 Nos2 Nos2-KO 12 SOD SOD1-KO 13 NF B B6;129P-Nfkb1tm1 Bal/J 14 D5 D5-KO 15 Gadd45 16 PARP1 17 ATG5 18 Fkbp11 19 TSCL 20 TGF 1 21 TGF 1 22 TGF 2 23 TGF 2 24 II Scn2b 25 II shRNA455/456 26 TCR (CMV-h-TCR)27 alpha(E)-catenin (B6.)

8 129-Ctnna1tm1 Efu/J)28 Alox15 29 Cdkn1a 30 Tmprss4 31 Tmprss2 010-60753039/010-60751212-8071