Transcription of POLARAMINE - database.japic.or.jp
1 1 1 2 3 4 7 1 1 1 g d- 10mg 2mg 1 d- 2 mg 2 1 2mg TTS363 TTS-363 d- 1 2 mg 1 1 4 1 (1) (2) (3) (4) (5) (6) 2 3 MAO MAO 4 (1)
2 1 2 3 22000 AMX0215814300 AMY00240 2008 12 1976 9 1965 9 1959 10 1975 12 1975 12 d- POLARAMINE 2019 7 11 2015 9 874419 2 3 1 ,2 (2) 5 AST GOT ALT GPT Al-P 1 2 5 6 7 8 PTP PTP PTP d- 4 mg 3 1 2
3 Mg Cmax ng/mL T1/2 hr AUC ng hr/mL mean S. E. 1 in vitro d l ED50 g/L g/L d l 4 2 in vivo ED50 4 d- d-Chlorpheniramine Maleate 3S -3- 4-Chlorophenyl -N,N-dimethyl-3-pyridin-2-ylpropylamine monomaleate C16H19 ClN2 C4H4O4 100 N,N- 20D N,N- 10mL 100mm pH 100mL pH 111 115 C 1% 100g 500g 2mgPTP 1000 10 100 100 1000 1 Deringer, P M., et al. Lancet I 432 1976 2 Kanoh, T., et al. Lancet I 546 1977 3 109 1 59 1989 4 Roth, FE.
4 , et al. J, Pharmacol Exper Therap. 124 4 347 1958 336-8666 1 11 1 0120-989-813 FAX 048-816-4183 1 2 1 PLRT 3
