Prominence - Shimadzu

1 C196-E061 WHigh-Performance Liquid Research Use Only. Not for use in diagnostic procedures. This publication may contain references to products that are not available in your country. Please contact us to check the availability of these products in your names, products/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation, its subsidiaries or its affiliates, whether or not they are used with trademark symbol TM or .Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether or not they are used with trademark symbol TM or . Shimadzu disclaims any proprietary interest in trademarks and trade names other than its contents of this publication are provided to you as is without warranty of any kind, and are subject to change without notice.

2 Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication. Shimadzu Corporation, 2017 First Edition: July 2004, Printed in Japan 3655-02709-30 ANSletter size w430 h280 mmHow HPLC Should BeHigh-performance liquid chromatography (HPLC) is widely used in diverse fields such as pharmaceuticals, and biochemistry to chemistry, the environment , and food products. The Shimadzu Prominence high-performance liquid chromatograph achieves an exceptional level of performance in each of these fields. Prominence HPLC offers exceptional reliability and great expandability to support diverse applications from ultra-fast liquid chromatography to preparative LC, gel permeation chromatography (GPC), ion chromatography, and Performance Liquid Chromatograph w430 h280 How HPLC Should BeHigh-performance liquid chromatography (HPLC) is widely used in diverse fields such as pharmaceuticals, and biochemistry to chemistry, the environment , and food products.

3 The Shimadzu Prominence high-performance liquid chromatograph achieves an exceptional level of performance in each of these fields. Prominence HPLC offers exceptional reliability and great expandability to support diverse applications from ultra-fast liquid chromatography to preparative LC, gel permeation chromatography (GPC), ion chromatography, and Performance Liquid Chromatograph w430 h28045 High Performance Liquid ChromatographProminence Superb Performance and ExpandabilityProminence keeps becoming more incorporating state-of-the-art improvements developed based on feedback, Prominence systems offer customers an analytical system with high reliability, in addition to exceptional performance and application-specific systems are available that take advantage of the remarkable expandability of Prominence systems.

4 These systems represent a consolidation of our extensive instrument and analytical experience cultivated together with customers thus far. Examples of analysis using these application systems are available in our application database and featured in Application News bulletins and the member website Solutions components AdditivesResidual pesticides FragrancesFoodsChemical IndustryPlastics Solvents PaintsFiber and paperEnvironmentAtmosphere Drinking water Soil BiofuelsDrug ingredients Antibiotics and antimicrobialsHerbal medicines, natural productsVeterinary pharmaceuticalsPharmaceuticalsPump Check valve improvements provide more stable solvent delivery Stronger support for buffer solutions with high salt concentrationsQuaternary gradient unitAutosampler Multi-rinse function (max.)

5 Two solutions) achieves even lower carryoverSystem controller Remotely monitor instrument status using a portable terminal, such as an iPad Overlapping injection function results in shorter analysis timesPhotodiode array detector More sensitive variable optical path length preparative cell and improved baseline stability Enables complete separation of unseparated peaks or visualization of tiny peaks hidden behind primary components (i-PDeA/i-DReC functions)Fluorescence detector Data acquisition using multi-wavelength modeColumn oven Improved leakage detection (leak sensor) Improved separation in simultaneous analysis of multiple components by simultaneous control of up to four unitsIn analytical laboratories, it is necessary to ensure that there have been no errors or irregularities in the procedures used to obtain results from the acquired data.

6 Confirming test results and maintaining accurate analysis operational logs are also required. This is in order to ensure both the accuracy of the acquired data and the reliability of analysis Report Set visualizes software operations to ensure the reliability of analysis data. At the same time, the amount of time needed to confirm analysis results can be reduced to 1/2 or 1 Visualization of the Sequence of Analysis Operations Ensures Reliability and Reduces the Burden of Confirmation ProceduresInformation from a sequence of analyses (batch analysis), analysis results and conditions, and even the entire operational log from the start to the end of analysis procedures are summarized in a single PDF file (Report Set).

7 This simplifies confirmation of analysis results and operations, thereby ensuring reliability and reducing the burden of confirmation of the sequence of analysis results subject to visualization is automatically disabled, preventing the revision, substitution, or tampering of a result, revision, substitution and other forms of tampering with the analysis results is prevented. In addition, the visualized Report Set and the sequence of analysis results are linked, allowing individual analysis results data sets to be searched and checked report confirmation record can be left at any point in the analysis results report output as a PDF file. If any items have not been checked, an error is issued, preventing omissions in the report confirmation process.

8 In addition, electronic signatures can be used for the confirmation of the Report Set. These functions simplify on-screen confirmation, enabling paperless operations and heightening The Sequence of Analysis Results Is Automatically Protected Against Tampering3. Digitization of the Confirmation Process for the Analysis Results Report Enhances Productivity Report Set is a PDF file that gathers operational information (human-mediated operations and settings) scattered within the software, as well as batch (sequential analysis) reports and chromatography reports, and summarizes them in a single report. This Report Set can be created with a single operation. As with analytical data and method files, the PDF Report Set is produced and stored in a security-controlled database.

9 Also, the software that creates the PDF Report Set is incorporated in LabSolutions, so there is no need to apply separate validation for PDF creation : The LabSolutions Report Set function is intended for LabSolutions CS and LabSolutions ImprovementsStrong Support for Ensuring the Reliability of Analysis Data and Enhancing ProductivityWide Variety of Application Systems Available Amino Acid Analysis System Organic Acid Analysis System Reducing Sugar Analysis System Carbamate Analysis System Iminoctadine Analysis System Synthetic Antimicrobial Analysis System Bromate Analysis System Cyanide Analysis System Anionic Surfactant Analysis System Aldehyde Analysis System GPC System GPC Cleanup System Preparative System Co-Sense SeriesPreparation ofsamplesImplementation of analysisAnalysis conditionssettingsInstrumentparametersPe ak

10 IntegrationparametersBatchsettingsBreakd own of Other Reports Instrument parameter reports Data processing parameter reports Calibration curve reportsGeneration and storageof analytical dataCheckCheckerApproverApprovalLink(Bet ween data to the Report Set)Report SetOperational log reportsOther reportsChromatographyreportsBreakdown of the Report SetLoginInside the LabSolutions DatabasePDFL ogoutLogoutLoginLogoutLoginBatch reportsElectronic signatureElectronic signature45 High Performance Liquid ChromatographProminence Superb Performance and ExpandabilityProminence keeps becoming more incorporating state-of-the-art improvements developed based on feedback, Prominence systems offer customers an analytical system with high reliability, in addition to exceptional performance and application-specific systems are available that take advantage of the remarkable expandability of Prominence systems.