REGIONAL DRUG AND THERAPEUTICS CENTRE (NEWCASTLE)

1 REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts REGIONAL drug AND THERAPEUTICS CENTRE . (NEWCASTLE). cost comparison CHARTS. July 2019. 16/17 Framlington Place Newcastle upon Tyne NE2 4AB. INTRODUCTION. Charts are organised by BNF classification and show comparative costs at basic NHS prices (as of July 2019) for selected agents. Except where indicated otherwise, each chart shows the cost of 1 year1 of treatment at a standard daily dose (shown in brackets). The doses given are not intended to imply therapeutic equivalence and for some drug groups such as ACE inhibitors doses may vary according to indication. Additionally, in some therapeutic areas such as antibacterial drugs the duration of treatment may differ from that shown. The cost comparison charts are also available in Excel format to all stakeholders (under password protection) on our NHS website: The contents table on the following page has been formatted so that you can quickly navigate to specific charts by holding the cursor over the chart title and clicking your left mouse button whilst holding down the Ctrl key.

2 NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES. 1. 1 year in this case is equal to 364 days rather than 365 when 1 month equals 28 days. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts To navigate to the chart required, hover the cursor over the section required, press CTRL. and click with the left mouse button. CONTENTS by BNF 74 classification Page Dyspepsia and gastro-oesophageal reflux disease .. 5. Antispasmodics and other drugs altering gut motility .. 5. Antisecretory drugs and mucosal protectants .. 6. Acute diarrhoea .. 7. Chronic diarrhoea .. 7. Aminosalicylates .. 8. Rectal foams .. 9. Laxatives .. 10. Diuretics .. 11. Beta-adrenoceptor blocking drugs .. 12. Alpha-adrenoceptor blocking drugs .. 12. Drugs affecting the renin-angiotensin system .. 13.

3 Nitrates and other antianginal drugs .. 14. Calcium-channel blockers .. 15. Anticoagulants .. 16. Antiplatelet drugs .. 17. Lipid-regulating drugs .. 18. Bronchodilators .. 19. Corticosteroids .. 20. Corticosteroid & Bronchodilator Inhalers .. 21. & Inhaled therapy licensed for COPD .. 22. Cromoglicate & related therapy, leukotriene receptor antagonists, and phosphodiesterase type-4 inhibitors .. 23. 23. Hypnotics & anxiolytics .. 24. Atypical antipsychotics maintenance doses (adults with psychosis) .. 25. Atypical antipsychotics Low doses .. 26. Antidepressant drugs .. 27. CNS stimulants and drugs used for attention deficit hyperactivity disorder - Stimulant .. 28. CNS stimulants and drugs used for attention deficit hyperactivity disorder Stimulant - Methylphenidate MR only.

4 29. CNS stimulants and drugs used for attention deficit hyperactivity disorder Non-Stimulant30. Drugs used in nausea and vertigo .. 30. Analgesics .. 31. Opioid 32. Opioid analgesics patches only .. 33. MR Opioid analgesics .. 34. 2 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Strong opioid analgesics equipotent dose cost per 24 hours .. 35. Neuropathic pain .. 36. Antimigraine drugs (acute) .. 36. Antiepileptic 37. Drugs used in parkinsonism and related disorders - Dopamine-receptor agonists .. 38. Drugs used in parkinsonism and related disorders - Levodopa, COMT and MAO-B inhibitors .. 39. Nicotine dependence .. 40. Drugs for dementia .. 41. 5 Miscellaneous antimicrobial and anthelmintic drugs .. 42. Penicillins .. 42. Cephalosporins .. 43. Tetracyclines.

5 43. Quinolones .. 44. Miscellaneous antifungal drugs (including topical and gynaecological) .. 44. Insulins (prefilled pens and cartridges) .. 45. Needles For Pre-Filled And Reusable Insulin Pens - 4mm to 6mm .. 46. Needles For Pre-Filled And Reusable Insulin Pens - 8mm .. 47. Blood lancets .. 48. Blood glucose monitoring cost of 50 tests more than 10 .. 49. Blood glucose monitoring cost of 50 tests below 50. Antidiabetic drugs .. 51. Antidiabetic drugs Newer agents .. 52. Female sex hormones and their modulators Combination HRT preparations .. 53. Female sex hormones and their modulators Oestrogen only HRT patches .. 54. Female sex hormones and their modulators Oestrogen only HRT options .. 55. Bisphosphonates and other drugs affecting bone metabolism .. 56. Contraceptives combined hormonal contraceptives.

6 57. Contraceptives Progestogen-only contraceptives .. 58. Drugs for urinary retention .. 59. Drugs for urinary frequency, enuresis and incontinence .. 60. Drugs for erectile dysfunction .. 61. Prostate cancer .. 61. 9 Baby milks - Specialised formulas - Infant and child per 100g .. 62. Calcium and vitamin D .. 63. Vitamin D preparations - prevention .. 63. Vitamin D preparations treatment .. 64. Non-steroidal anti-inflammatory drugs .. 65. Rubefacients, topical NSAIDs, capsaicin, and poultices .. 66. Other anti-Inflammatory preparations .. 66. 3 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Treatment of Glaucoma .. 67. Tear Deficiency, Ocular Lubricants, and Astringents .. 68. Nasal steroids .. 68. Emollients (by volume) .. 69. Emollients per 100g/ml.

7 70. Emollient bath and shower preparations per 100g/ml .. 71. Topical Corticosteroids .. 72. Topical Corticosteroids with antimicrobial .. 73. Topical scalp preparations/Shampoos for eczema and psoriasis .. 73. Steroid and vitamin D topical preparations .. 74. Topical preparations for acne .. 74. Stoma adhesive removers .. 75. Patent expiry table July 2019 to June 2020 .. 76. 4 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Dyspepsia and gastro-oesophageal reflux disease July 2019: Dyspepsia and gastro-oesophageal reflux disease - cost of 1 year's treatment Maalox Plus . (30 ml) Magnesium Trisilicate suspension (30 ml) Compound alginate suspension (Gaviscon Advance 20 ml) Compound alginate suspension (Acidex 40 ml) Co-magaldrox 195/220. suspension (Mucogel 30 ml) Compound alginate suspension (Peptac 40 ml) 0 20 40 60 80 100 120 140.

8 Doses given do not imply therapeutic equivalence copyright RDTC 2019. Antispasmodics and other drugs altering gut motility July 2019: Antispasmodics and other drugs altering gut motility - cost of 1 year's treatment Dicycloverine (30 mg) 2, Fybogel Mebeverine sachets (1 BD) Propantheline (15 mg TDS) Kolanticon gel (40 ml) Peppermint oil (Colpermin ) capsules (1 TDS) Hyoscine butylbromide (20 mg QDS) Mebeverine MR. (200 mg BD) Peppermint oil (Mintec ) capsules (1 TDS) Mebeverine (135 mg TDS) Alverine (60 mg TDS) 0 500 1,000 1,500 2,000 2,500 3,000. Doses given do not imply therapeutic equivalence copyright RDTC 2019. Contents 5 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Antisecretory drugs and mucosal protectants July 2019: Antisecretory drugs and mucosal protectants - cost of 1 year's treatment Famotidine (40 mg OD) Misoprostol (200 micrograms QDS) Cimetidine (400 mg BD) Nizatidine (300 mg OD) Losec tablets (20 mg OD) Omeprazole tablets (20 mg OD) Lansoprazole tablets (30 mg OD) Esomeprazole (20 mg OD) Rabeprazole (20 mg OD) Pantoprazole (40 mg OD) Ranitidine (150 mg BD) Lansoprazole capsules (30 mg OD) Ranitidine (300 mg OD) Omeprazole capsules (20 mg OD) 0 100 200 300 400 500 600.

9 Doses given do not imply therapeutic equivalence copyright RDTC 2019. Contents 6 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Acute diarrhoea July 2019: Acute diarrhoea - cost of 5 days treatment Loperamide 2mg tablets Codeine 30mg tablets Loperamide 2mg capsules 0 1 2. Doses given do not imply therapeutic equivalence copyright RDTC 2019. Chronic diarrhoea July 2019: Chronic diarrhoea - cost of 1 year's treatment Loperamide 2mg tablets (8mg daily, divided doses) Loperamide 2mg capsules (8mg daily, divided doses) 0 10 20 30 40 50 60 70 80 90. Doses given do not imply therapeutic equivalence copyright RDTC 2019. Contents 7 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Aminosalicylates July 2019: Inflammatory bowel diseases - cost of 28 days treatment Olsalazine capsules (3g max single dose 1g) Asacol 400mg or 800mg tablets ( daily in 2-3 divided doses) Mezavant XL tablets ( once daily) Octasa 800mg tablets ( daily in 2-3 divided doses) Pentasa tablets/granules Treatment (4g daily in 2-3 divided doses) Colazide capsules ( three time daily) Salofalk tablets (3g daily in 3 divided doses) Salofalk granules (3g once daily) Octasa 400mg tablets ( once daily) Olsalazine capsules (500mg twice daily) Asacol 400mg or 800mg tablets ( daily in 2-3 divided doses) Mezavant XL tablets ( once daily) Octasa 800mg tablets ( once daily) Maintenance Pentasa tablets/granules (2g once daily) Salofalk tablets ( daily in 3 divided doses) Colazide capsules ( twice daily)

10 Salofalk granules ( daily in 3 divided doses) Octasa 400mg tablets ( once daily) 0 100 200 300 400 500. Doses given do not imply therapeutic equivalence copyright RDTC 2019. Contents 8 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Rectal foams July 2019: Rectal foams - cost of 14 days treatment Prednisolone 20mg/application foam enema Budenofalk 2mg foam enema Colifoam 10% aerosol 0 20 40 60 80 100 120 140 160 180 200. Doses given do not imply therapeutic equivalence copyright RDTC 2019. Contents 9 Jul 2019. REGIONAL drug and THERAPEUTICS CENTRE cost comparison charts Laxatives July 2019: Laxatives - cost of 14 days treatment Prucalopride 2 mg (Resolor ) Naloxegol 25mg (Moventig ) Linaclotide 290mcg (Constella ) Sodium citrate enema (Micolette 1 daily) Sodium picosulfate 5 mg/5 ml oral solution (10 ml) Macrogols (2 sachets for 14 days) Manevac (8 g) Ispaghula husk (Fybogel 2 sachets) Bisacodyl (10 mg) Sterculia (Normacol 10 g) Docusate (200 mg) Methylcellulose (2 g) Glycerol suppository (4 g) Lactulose (20 ml) Senna (15 mg) 0 5 10 15 20 25 30 35.