製品安全データシート - RYOUSAIKENBO

1 MSDS 1/3 1-2-3 (086)801-7721 (086)231-4081 2002 11 22 2009 07 16 -D-glucopyranosyl -D-glucopyranoside dihydrate 8-674 8-(4)-1368 CAS No. 6138-23-4 INCI Name Trehalose EINECS No. 202-739-6 12 22 11 2 OOHOHHO 2H2 OOHOOOHOHOHHO 12 22 11 CAS No. 99-20-7 MSDS 2/3 97 C /100 20 C 1 1 LD50 16g/kg 2

2 90 3 4 5,6 7,8 9 10 11 12,13,14 MSDS 3/3 1) ( ) 2) Trehalose crystals acute oral toxicity to the rat (Huntingdon Research Centre Ltd., HBL 4/940826/AC) 3) Subchronic 13-week oral toxicity (feeding) study with trehalose in mice (RCC, RCC project 639213) 4) Trehalose (crystal) bacterial mutation assay (Huntingdon Research Centre Ltd., HBL 3/941649) 5) Evaluation of trehalose in the CHO chromosome aberration assay (SRI International, SRI Study No.

3 G018-97) 6) Evaluation of trehalose in the mouse micronucleus assay (SRI International, SRI Study No. G019-97) 7) Oral embryotoxicity/teratogenicity study with trehalose in rats (TNO Nutrition and Food Research Institute, Project No. 471003) 8) Oral embryotoxicity/teratogenicity study with trehalose in New Zealand White rabbits (TNO Nutrition and Food Research Institute, Project No. 471005) 9) Oral two-generation reproduction study with trehalose in rats (TNO Nutrition and Food Research Institute, Project No. 471004) 10) Trehalose skin irritation to the rabbit (Huntingdon Life Sciences Ltd., HBL 001/013015/SE) 11) Trehalose eye irritation to the rabbit (Huntingdon Life Sciences Ltd.

4 , HBL 002/013070/SE) 12) Clegg J. S., Comp. Biochem. Physiol., 14, 135 (1965) 13) 29(8), 451 (1982) 14) 17(3), 601 (1991)