SAFETY DATA SHEET Page: 1 of 6 Bee Venom PLA2 …

1 06/28/2016 Revision:Page: 1 of 6 Bee Venom PLA2 ControlSAFETY data SHEET05/07/2015 Supersedes Revision:according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272 Product Code:Section 1. Identification of the Substance/Mixture and of the Company/UndertakingBee Venom PLA2 Control Product Name:Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Arbor, MI 48108 CHEMTREC Within USA and Canada:Emergency Contact:+1 (800)424-9300 CHEMTREC Outside USA and Canada:+1 (703)527-3887 Cayman Chemical CompanyInformation:+1 (734)971-3335 For research use only, not for human or veterinary identified site address:PLA2 Type III (bee Venom ) Control; Secretory sPhospholipase A2 (bee Venom ) Control; sPLA2(bee Venom ) Control; Details of the Supplier of the SAFETY data Relevant identified uses of the substance or mixture and uses advised Emergency telephone number:Section 2.

2 Hazards Classification of the Substance or Mixture:Based on evaluation of currently available data this substance or mixture is not classifiable according to Hazard Label Elements:NoneGHS Signal Word:No phrases Precaution Phrases:No phrases Response Phrases:Please refer to Section 7 for Storage and Section 13 for Disposal Storage and Disposal Alert - Bee Stings: This product has the potential to cause a similar reaction to a bee stingupon accidental injection of product or if breaking of contaminated glassware causes a ConditionsGenerally Aggravated ByExposure:Material may be irritating to the mucous membranes and upper respiratory be harmful by inhalation, ingestion, or skin cause eye, skin, or respiratory system the best of our knowledge, the toxicological properties have not been thoroughly Human HealthEffects and Symptoms:CAS # /RTECS #Hazardous Components (Chemical Name)/REACH Registration 3.

3 Composition/Information on IngredientsConcentrationEC Index ClassificationNANAApis mellifera, Arthropod %NA NANo data available. 77-86-1TY2900000 Trizma %201-064-4 NASkin Corr. 2: H315 Eye Damage 2: H319 STOT (SE) 3: H335 Multi-region format06/28/2016 Revision:Page: 2 of 6 Bee Venom PLA2 ControlSAFETY data SHEET05/07/2015 Supersedes Revision: 7647-14-5VZ4725000 Sodium %231-598-3 NAEye Damage 2A: H319 9048-46-8AY9296000 Bovine Serum Albumin (BSA) %232-936-2 NAAcute Tox.(O) 4: H302 %231-791-2 NANo data 4. First Aid MeasuresDescription of First AidMeasures:Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyesexamined and tested by medical Case of Eye Contact:Immediately wash skin with soap and plenty of water for at least 15 minutes. Removecontaminated clothing.

4 Get medical attention if symptoms occur. Wash clothing before Case of Skin Contact:Wash out mouth with water provided person is conscious. Never give anything by mouth to anunconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so bymedical Case of Ingestion:Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trainedpersonnel. Get immediate medical Case of 5. Fire Fighting MeasuresFlash Pt:No in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved orequivalent), and full protective gear to prevent contact with skin and Fighting Instructions:Autoignition Pt:No Limits:LEL: No data . UEL: No alcohol-resistant foam, carbon dioxide, water, or dry chemical water spray to cool fire-exposed ExtinguishingMedia:A solid water stream may be ExtinguishingMedia:No data Properties data 6.

5 Accidental Release MeasuresContain spill and collect, as to a chemical waste container for disposal in accordance with local and Material ForContainment and CleaningUp:Avoid breathing vapors and provide adequate conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,and appropriate personal protection (rubber boots, SAFETY goggles, and heavy rubber gloves).Protective Precautions,Protective Equipment andEmergency Procedures:Take steps to avoid release into the environment, if safe to do :Multi-region format06/28/2016 Revision:Page: 3 of 6 Bee Venom PLA2 ControlSAFETY data SHEET05/07/2015 Supersedes 7. Handling and StorageAvoid breathing dust/fume/gas/mist/ prolonged or repeated To Be Takenin Handling:Keep container tightly in accordance with information listed on the product To Be Takenin Storing:Section 8.

6 Exposure Controls/Personal ProtectionBritain EH40 France VLCAS #Partial Chemical Exposure Parameters:No data . NAApis mellifera, Arthropod venomNo data . 77-86-1 Trizma baseNo data . 7647-14-5 Sodium chlorideNo data . 9048-46-8 Bovine Serum Albumin (BSA)No data . 7732-18-5 WaterNo TWAACGIH TWACAS #Partial Chemical NameOther LimitsNo data . NAApis mellifera, Arthropod venomNo data . 77-86-1 Trizma baseNo data . 7647-14-5 Sodium chlorideNo data . 9048-46-8 Bovine Serum Albumin (BSA)No data . 7732-18-5 WaterNo approved respirator, as conditions Equipment(Specify Type): SAFETY glassesEye Protection:Compatible chemical-resistant glovesProtective Gloves:Lab coatOther Protective Clothing:Use process enclosures, local exhaust ventilation, or other engineering controls to control airbornelevels below recommended exposure Controls(Ventilation etc.)

7 :Do not take storing or utilizing this material should be equipped with an eyewash facility and a thoroughly after Practices:No data Exposure Personal protection equipment:Multi-region format06/28/2016 Revision:Page: 4 of 6 Bee Venom PLA2 ControlSAFETY data SHEET05/07/2015 Supersedes Revision:Section 9. Physical and Chemical PropertiesPhysical States:[ ] Gas [ X ] Liquid [ ] SolidMelting Point:No Point:No Pt:No Limits:LEL: No data . UEL: No Pressure (vs. Air or mmHg):No Density (vs. Air = 1):No Rate:No l of bee Venom PLA2 in 10 mM Tris-HCl, pH , containing NaCl and and Information on Basic Physical and Chemical PropertiesFlammability (solid, gas):No data Gravity (Water = 1):No in Water:No Pt:No Volatile:No Other 10.

8 Stability and ReactivityNo data To Avoid:Unstable [ ] Stable [ X ]Stability:No data - MaterialsTo Avoid:No data orByproducts:Will occur [ ] Will not occur [ X ]Polymerization:Stable if stored in accordance with information listed on the product Note(s):No data #Hazardous Components (Chemical Name)NTPS ection 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly onToxicological Effects:IARCACGIHOSHANTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity: NAApis mellifera, Arthropod 77-86-1 Trizma 7647-14-5 Sodium 9048-46-8 Bovine Serum Albumin (BSA) format06/28/2016 Revision:Page: 5 of 6 Bee Venom PLA2 ControlSAFETY data SHEET05/07/2015 Supersedes release into the from fire control or dilution water may cause :Section 12.

9 Ecological InformationNo data andDegradability:No data :No data in Soil:No data of PBT and data adverse in accordance with local, state, and federal Disposal Method:Section 13. Disposal ConsiderationsSection 14. Transport InformationNot dangerous Proper Shipping Name:DOT Hazard Class:UN/NA LAND TRANSPORT (US DOT):Not dangerous Shipping LAND TRANSPORT (European ADR/RID):UN Number:Hazard Class:Not dangerous Shipping AIR TRANSPORT (ICAO/IATA):Transport in accordance with local, state, and federal TransportInformation:CAS #Hazardous Components (Chemical Name)Section 15. Regulatory InformationS. 302 (EHS)S. 304 RQS. 313 (TRI)EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists NAApis mellifera, Arthropod venomNoNoNo 77-86-1 Trizma baseNoNoYes-Cat. N106 7647-14-5 Sodium chlorideNoNoNo 9048-46-8 Bovine Serum Albumin (BSA)NoNoNo 7732-18-5 WaterNoNoNoCAS #Hazardous Components (Chemical Name)Other US EPA or State Lists NAApis mellifera, Arthropod venomCAA HAP,ODC: No; CWA NPDES: No; TSCA: No; : No 77-86-1 Trizma baseCAA HAP,ODC: HAP; CWA NPDES: No; TSCA: Yes -Inventory; CA : No 7647-14-5 Sodium chlorideCAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -Inventory; CA : No 9048-46-8 Bovine Serum Albumin (BSA)CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -Inventory; CA : NoMulti-region format06/28/2016 Revision:Page: 6 of 6 Bee Venom PLA2 ControlSAFETY data SHEET05/07/2015 Supersedes Revision: 7732-18-5 WaterCAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -Inventory.

10 CA : NoThis SDS was prepared in accordance with 29 CFR and Regulation (EC) InformationStatement:Section 16. Other InformationNo data Information AboutThis Product:DISCLAIMER: This information is believed to be accurate and represents the best informationcurrently available to us. However, we make no warranty of merchantability or any other warranty,express or implied, with respect to such information, and we assume no liability resulting from itsuse. Users should make their own investigations to determine the suitability of the information fortheir particular Policy or Disclaimer:06/28/2016 Revision Date:Multi-region format