SAFETY DATA SHEET (SDS) ZINC OXIDE - Numinor

1 92 Maalot, 24952 Israel Tel. 972 4 9978 220, Fax. 972 4 9976 062 Page 1 of 6 SAFETY data SHEET (SDS) zinc OXIDE SECTION 1 IDENTIFICATION OF THE SUBSTANCE AND OF THE COMPANY Manufacturer & Supplier: Numinor CHEMICAL INDUSTRIES LTD. Address: P. O. BOX 92, MAALOT 24952, ISRAEL. Tel: + 972-4-9978220 Fax: + 972-4-9976062 E-Mail: Web Site: Emergency Contact: Mr. Nir Baram, +972 54 587 3131 Product Name: zinc OXIDE Formula: ZnO Synonyms: Calamine, zinc white, Chinese white, Flowers of zinc Primary Use: Chemical reagent for rubber compounding, ceramics, animal feed additive (trace element), zinc chemicals production, paints, plastics, polymers, cosmetics, pharmaceutical and electronics. SECTION 2 - HAZARDS IDENTIFICATION Classification according to Regulation (EC) 1272/2008 (GHS-CLP) According to Regulation (EC) No1272/2008 Acute aquatic toxicity (Category 1) Chronic aquatic toxicity (Category 1) According to European Directive 67/548/EEC as amended.

2 Very toxic to aquatic organisms may cause long-term adverse effects in the aquatic environment. GHS Pictogram: Signal Word: Warning Hazard Statements: H410 Very toxic to aquatic life with long lasting effects. Precautionary Statements: P273 Avoid release to the environment. P391: Collect spillage. P501 Dispose of contents/container in accordance with local/regional/national/international regulation. 92 Maalot, 24952 Israel Tel. 972 4 9978 220, Fax. 972 4 9976 062 Page 2 of 6 SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS Formula: ZnO Molecular Weight:: g/mol Appearance & Odour: Solid powder (fine), white to off white colour. Yellow-brown for Feed Grade CAS-No 1314-13-2 EC-No. 215-222-5 Index-No. 030-013-00-7 Classification Aquatic Acute 1; Aquatic Chronic 1; H410 SECTION 4 - FIRST AID MEASURES Effects and symptoms: Chills, fever, nausea, vomiting, coughing, weakness and headaches, skin irritation.

3 First aid - Skin contact: Wash immediately with plenty of water and soap/ - Inhalation: Remove victim to fresh air. Clean nasal cavity with water. Give oxygen if breathing difficulty. Seek medical attention. If feeling unwell, immediately seek medical attention. - Eye contact: Rinse immediately with clean water for 15 minutes. If feeling unwell, immediately seek medical attention. - Ingestion: Immediately rinse mouth with water. Do not induce vomiting. Give large quantities of water or milk to drink. If feeling unwell, immediately seek medical attention. Protection of rescue personnel: Avoid all unnecessary exposure. Use appropriate protection (see Section 9). SECTION 5 FIRE, FIGHTING & EXPLOSION data Fire: Non Combustible. Flammability: Non Flammable Flash point: Not Combustible Extinguishing media: In case of fire in immediate vicinity use any extinguishing agent.

4 Protection of fire-fighters: Use breathing apparatus (self-contained breathing apparatus with full face shield). Wear suitable protective clothing. Hazardous combustion and: None. Decomposition products SECTION 6 - ACCIDENTAL RELEASE MEASURES & SPILL LEAK PROCEDURES Personal precautions: Wear suitable gloves and eye/face protection. Avoid dust creation. Environmental precautions: Avoid allowing product to enter drains, sewage system, and ground water. Methods for cleaning up: Sweep up and shovel into suitable containers for disposal. Re-use or recycle waste. 92 Maalot, 24952 Israel Tel. 972 4 9978 220, Fax. 972 4 9976 062 Page 3 of 6 SECTION 7 - HANDLING AND STORAGE Handling & storing: Good housekeeping - store in a cool dry place - keep containers shut. Avoid making dust. Avoid moisture. Packing Materials: All materials suitable. SECTION 8 - EXPOSURE CONTROL / PERSONAL PROTECTION - Respiratory protection: Respiratory protection equipment necessary when dust is apparent Type P1 respirator (EN 143).

5 - Hand protection: Protective Gloves. Material: leather gloves, cotton gloves, rubber gloves. - Skin protection: Work clothes. - Eye protection: Chemical goggles or SAFETY glasses. - Engineering measures: Mechanical ventilation is recommended. SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES Form: powder Melting Point: not available Solubility in water: In soluble Appearance & Odour: White to off white colour for technical grades, yellow-brown for Feed Grades Density: g/cm3 SECTION 10 - STABILITY & REACTIVITY data Stability: Stable under ordinary conditions, avoid moisture. Hazardous Reactions: Hazardous decomposition products formed under fire conditions - zinc oxides, Incompatibility (materials to avoid): Strong oxidizing agents. Avoid moisture SECTION 11 TOXILOGICAL INFORMATION Acute effects (acute toxicity, irritation and corrosivity) Slightly hazardous in case of skin contact (irritant), of ingestion May cause mild skin irritation Acute toxicity(oral) LD50 (mouse): 7950 kg/mg OECD 401 Type of test Route of exposure Species observed Dose/duration Details of toxic effects LDL0 Lowest published lethal value Oral Human 500 mg/kg Not reported other than lethal dose TDLo values to mammals in oral exposure, mg/kg : 6846 Acute toxicity(Inhalation) TCLo values to mammals in inhalation exposure, mg/kg : 600.

6 LD50 values to mammals in non-oral exposure mg/kg : 240 92 Maalot, 24952 Israel Tel. 972 4 9978 220, Fax. 972 4 9976 062 Skin irritation page 4 of 6 skin, rabbit, 500 mg, 24 hr, mild. zinc OXIDE is irritant on skin in the case of humans. Skin inflammation is characterized by itching, scaling, reddening and occasionally blistering. Eye irritation Slightly irritating (rabbit). Slight erythema of the conjunctiva for 2 days, no effect on iris and cornea. Sensitisation No sensitizing potential (guinea pig), Magnusson & Kligman CMR effects (carcinogenicity, mutagenicity and toxicity for reproduction) Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast. Mutagenic Effects May affect genetic material (mutagenic).

7 Reprotoxic Effects May cause adverse reproductive effects based on animal data . Carcinogenic Effects No evidence of carcinogenicity in laboratory animals or in man. Other Toxic Effects on Humans: Inhalation: May cause mechanical irritation of the respiratory tract. A few sources claim that finely divided zinc OXIDE dust can cause "metal fume fever." zinc OXIDE dust is generally considered a nuisance dust; adverse effects are unlikely when exposures are kept under reasonable control. Inhalation of high concentrations of zinc OXIDE fume or dust may cause "Metal Fume Fever." Symptoms of metal fume fever may include a flu-like condition involving headache, chills, fever, sweats, nausea, vomiting, cough, muscle aches and pains, and difficulty breathing, ;pulmonary edema. May also affect the liver. Eyes: May cause mechanical eye irritation and conjunctivitis, redness or pain Ingestion May cause digestive tract irritation although zinc OXIDE has a low toxicity by oral exposure route.

8 Prolonged or repeated ingestion of zinc OXIDE may affect blood, metabolism, and the thyroid. Studies in animals indicate that doses as high as 200 mg/kg have caused reduced fatal body weight and fetal death. Chronic toxicity NOAEL: 50 mg Zn/day (based on human clinical studies). NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 500 mg/m3 ORAL (LD50): Acute: 7950 mg/kg [Mouse] LD50 values to mammals in non-oral exposure , mg/kg : 240 TDLo values to mammals in oral exposure, mg/kg : 6846 TCLo values to mammals in inhalation exposure, mg/kg : 600 SPECIES: Colinas Virginians, ENDPOINT: LD50 , VALUE: 566 mg/kg 92 Maalot, 24952 Israel Tel. 972 4 9978 220, Fax. 972 4 9976 062 Page 5 of 6 SECTION 12 - ECOLOGICAL INFORMATION Ecotoxicity Species Type of Exposure Duration Endpoint Value Lepomis macrochirus Static 96 hr LC50 >320 ppm Oncorhynchus mykiss Static 96 hr LC50 ppm Colinas Virginians oral via capsule LD50 566 mg/kg Colinus virginianus dietary 8 days LC50 > 5000 ppm Mobility Not applicable Persistence and degradability Rapidly Degradable: No DEGREDATION: Readily degradable = No Bioaccumulative potential Bioaccumulative: ND, Bioconcentration: Low Bioconcentration Toxicity of the Products of Biodegradation The product itself and its products of degradation are not toxic.

9 SECTION 13 - DISPOSAL CONSIDERATIONS Disposal: Keep waste separate. Because of possible pollution, remove as industrial waste or hazardous waste (EWC code 060316, 150110). Waste of residues: This material and its container should be labeled Hazardous Goods. Contaminated packaging: Keep waste packaging separate. Waste should be disposed of in a permitted chemical waste facility. SECTION 14 - TRANSPORT INFORMATION ADR/RID UN-Number: 3077, Class: 9, Packing group: III Proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, ( zinc OXIDE ) IMDG UN-Number: 3077, Class: 9 ,Packing group: III EMS-No: F-A, S-F Proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, ( zinc OXIDE ) Marine pollutant: Yes IATA UN-Number: 3077, Class: 9 , Packing group: III Proper shipping name: Environmentally hazardous substance, solid, ( zinc OXIDE ) Other: EHS-Mark required (ADR , IMDG code ) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.

10 92 Maalot, 24952 Israel Tel. 972 4 9978 220, Fax. 972 4 9976 062 Page 6 of 6 SECTION 15 REGULATORY INFORMATION Classification according to Regulation (EC) 1272/2008 (GHS-CLP). This SAFETY data SHEET complies with EC regulation No. 1907/2006/ SECTION 16 - OTHER INFORMATION Text of H-code(s) and R-phrase(s) mentioned in Section 3 Aquatic Acute Acute aquatic toxicity Aquatic Chronic Chronic aquatic toxicity H410 - Very toxic to aquatic life with long lasting effects. N - Dangerous for the environment R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Date of Issue: October 2010 Last update: October 2010 MSDS prepared by: AVK Disclaimer: As the conditions or methods of use are beyond our control, we do not assume any responsibility and expressly disclaim any liability for any use of the material. Information contained herein is believed to be true and accurate but all statements or suggestions are made without any warranty, express or implied, regarding accuracy of the information, the hazards connected with the use of the material or the results to be obtained from the use thereof.