Sample Comprehensive Celiac Disease Panel

1 Sample Celiac Disease Comprehensive Panel report Test Name Test Ordered Celiac Disease Comprehensive Panel *. Interpretation Serological evidence for Celiac Disease is present. Consider IgA deficiency. Reference Level of Tissue Transglutaminase Test Results Flag Range Antibody Detected An IgA and/or IgG test is used to detect antibodies directed at this <4 U/mL: TISSUE TRANSGLUTAMINASE AB, IGA No Antibody Detected ABSENT. enzyme commonly found in the <1 <4 U/mL: (tTg IgA) >4 U/mL: No Antibody Detected intestines. Antibody Detected 24-121 LOW. IGA, SERUM.

2 22 L Consider IgA deficiency as (Total IgA) mg/dL number is not in the normal range of 24-121 mg/dL. <6 U/mL: TTG ANTIBODY, IGG No Antibody Detected PRESENT. 24 H >6 U/mL: (tTg IgG) >6 U/mL: Antibody Detected Antibody Detected Confirmation ENDOMYSIAL ANTIBODY SCR (IGA) POSITIVE. W/REFL TO TITER POSITIVE NEGATIVE EMA IgA confirms the These tests usually correlate with (EMA) positive tTG IgG. tTg. However, it is ordered as a confirmation when patients have ENDOMYSIAL ANTIBODY TITER 1:160 H <1:5 TITER. had positive results from other Celiac Disease antibody tests.

3 Results out of range Interpreting Celiac Disease Comprehensive Panel Test Results No Indication of Celiac Disease Inconclusive Suggestive of Celiac Disease Highly Suggestive of Celiac Disease tTg IgA=Positive tTg IgA=Negative tTg IgA=Positive tTg IgA=Negative Total IgA=Normal Total IgA=Low Total IgA=Normal Total IgA=Normal EMA=Negative tTG lgG=Positive EMA=Positive tTg IgA=Negative tTg IgA=Positive tTg IgA=Negative Total IgA=Low Total IgA=Low Total IgA=Low tTG IgG=Positive tTG IgG=Positive tTG IgG=Negative EMA=Negative EMA=Positive tTg IgA=Positive tTg IgA=Negative Total IgA=Low Total IgA=Low tTG IgG=Positive tTG IgG=Positive EMA=Negative EMA=Positive If test results do not suggest the presence of Celiac Disease , confirm your patient was eating a normal, gluten-containing diet for at least 2 weeks prior to getting tested.

4 If not, the test results may have been compromised. If the patient was eating normally, there is a chance he or she has non- Celiac gluten sensitivity. *For children up to age 4, use the Celiac Disease Comprehensive Panel , Infant. Copyright 2014 Quest Diagnostics Incorporated. Quest, Quest Diagnostics, , any associated logos, and all associated Quest Diagnostics registered and unregistered trademarks are the property of Quest Diagnostics. All third-party marks and are the property of their respective owners.