SARMs in Dietary Supplements - OPSS

1 BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 SARMs in Dietary Supplements and Other ProductsSelective androgen receptor modulators, or SARMs , are syn-thetic drugs designed to mimic the effects of testosterone. Al-though these drugs are still in the research and testing stages of development, and they are classified as drugs, yet most are readily available online both as ingredients in Dietary supple-ment products and as chemicals available for research only. Some websites marketing SARMs for research use include descriptions with language clearly targeting use for bodybuild-ing. However, according to FDA Body-building products that contain selective androgen receptor modulators, or SARMs , have not been approved by the FDA and are associated with serious safety concerns, including potential to increase the risk of heart attack or stroke and life threatening reactions like liver damage.

2 They re also prohibited for use in sport. For exam-ple, a 2017 FDA Safety Alert describes andarine and ostarine as unapproved drugs and anabolic steroid-like substances. In addition, some experimental drugs that are not SARMs are being marketed as or along with SARMs , but they are equally illegal in Dietary Supplements and prohibited for sport. As a result, the most common of these are also included on the next page. In addition, there are Dietary Supplements marketed as SARMs that do not contain any of the drugs listed here. The following list will help you recognize these drugs, which often go by various names, as well as currently available products that contain LGD-3033 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifl uoroethyl)-3H-pyrrolo[3,2-f]quinolin-7(6 H)-one LGD-4033 or LGD4033 Ligandrol 4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxye thyl)pyrroli-din-1-yl)-2-(trifluoromethy l)benzonitrile MK-2866 or MK2866 Enobosarm Ostarine GTX- 024 (2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(tr ifluoro-methyl)phenyl]-2-hydroxy-2-methy lpropanamide (R)-Ostarine (2R)-3-(4-cyanophenoxy)-N-[4-cyano-3-(tr i-fluoromethyl)phenyl]-2-hydroxy-2-methy lpro-panamide R A D -14 0 or R A D14 0 Testolone 2-chloro-4-((1R,2S)-1-(5-(4-cyanophenyl) -1,3,4-oxadi-azol-2-yl)-2-hydroxypropyla mino)-3-methylbenzonitrile 2-[4-chlorobutyl(methyl)amino]-N-(2,6-di methylphe-nyl)acetamide S-22 or S22 2-[[2-(diethylamino)acetyl]amino]-4-meth -yl-5-(2-methylsulfanylethyl)

3 -1H-pyrrole-3- carboxamide S-4 or S4 Andarine GTX-007 (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2- meth-yl-N-[4-nitro-3-(trifluoromethyl)ph enyl]propanamide Y K -11 Y K -11- O A methyl (2E)-2-[(8R,9S,10R,13S,14S,17R)-2 -me-t h ox y -2 ,13 - d i m e t hy l - 3 - oxo s p i r o [1, 2, 6 ,7, 8 ,9,10,11,12,14,15,16-dodecahydrocyclopen ta[a]phenanthrene-17,5 -1,3-dioxolane]-4 -ylidene]acetate YK-500 (17- ,20E)-17,20-[(1-methoxyethylidene)bis(ox y)]-3-oxo-19-norpregna-4,20-diene-21-car boxylic acid methyl ester)CREATED BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 Product NameDistributor or Manufacturer Ingredients on label/advertising (** denotes research labeling/advertising; not labeled as a Dietary supplement )4S InvitroSARM TechLGD-4033, S4, MK-2866 AlphamassOmega Labs4-((R)-2-((R)-2,2,2-trifluoro-1-hydr oxyethyl)pyrrolidin-1-yl)-2-tri-fluoroMe thyl)benzonitrileAnabol LGD4033 Pureline NutritionLGD 4033-Anabolicum-4(( R)-2-(( R )-2,2,2-trifluoro-1-hy-droxyethyl)pyrrol idin-1-yl_-2-trifluoroMethyl)benzonitril eAnabolicum LGD-4033 SARMSX**Anadrine S4 Pureline NutritionAndarine - SARM (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2 -methyl-N-( )-propionamide)Andarin S4 Hardcore FormulationsSelect Androgen Receptor Modulator Andarin-S4 Andarin S4 Landmark Research(Andarin) SrAndarine (S4)Cratus LabsS4 Andarine (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2 -meth-yl-N-( )-propionamide)Andarine HardcoreMuscle Science(2S)-3-(4-acetamido-phenoxy)-2-hy droxy-2-methyl-N-( )-propionamide)

4 Andarine S-4 Medals Research**Andarine S-4 SARMSX**Other Chemicals Sold as SARMs GW-501516 or GW501516 * Cardarine Endurobol GSK-516 GW-1516 {4-[({4-methyl-2-[4-(trifluoromethyl)phe nyl]-1,3-thi-azol-5-yl}methyl)sulfanyl]- 2-methylphenoxy}acetic acid 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoro methyl)phenyl]-1,3-thiazol-5-yl]methylsu lfanyl]phenoxy]acetic acid SR-9009 Ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothio phen-2-yl)methyl]amino]methyl]pyrrolidin e-1-carboxylate MK-677 or MK-0677 or MK677 Ibutamoren L 16 3 ,191 2-amino-2-methyl-N-[(2R)-1-(1-methylsulf onyl-spiro[2H-indole-3,4 -piperidine]-1 -yl)-1-oxo-3-phenylmethoxypropan-2-yl]pr opanamide Ibutamoren mesylate Crescendo 2-amino-2-methyl-N-[(2R)-1-(1-methylsulf onyl-spiro[2H-indole-3,4 -piperidine]-1 -yl)-1-oxo-3-phenylmethoxypropan-2-yl]pr opanamide;meth-anesulfonic acid* Note: In 2013, the original developer discontinued GW501516 due to the discovery of severe toxic effects, and the World Anti-Doping Authority (WADA) issued an alert strongly warning against its use.

5 Nevertheless, it is still widely available online. The list below includes both Dietary supplement products and research products currently available. The latter do not have the labeling required for Dietary Supplements . Current refers to anything that could be purchased online as of the date on this list, including some products that have apparently been discontinued by their manufacturer or distributor but that can still be obtained from other sources online. The list is a far-from-complete representation of research suppliers, as there are too many to include them all; some may legitimately sell only to research BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 Product NameDistributor or Manufacturer Ingredients on label/advertising (** denotes research labeling/advertising; not labeled as a Dietary supplement )Andarine S4 Brawn NutritionANDARINE / S4 (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2 -methyl-N-( )-propionamide)Andarine S4 Intel PharmaAndarine (S4)Andarine S4 Panther Sports NutritionAndarineBehemothBeast Biotech UKMK2866, LGD4033 Black MagicMedFit RxRAD-140, LGD-4033, GW-501516 BrawnKodiak LabsSARM LGD-4033 (Ligandrol)Carda RippedMuscle Science{4-[({4-methyl-2-[4-(trifluoromet hyl)phenyl]-1,3-thiazol-5-yl}methyl)sulf anyl]-2-methylphenoxy}acetic acidCardar1neOlympus UKphenyl]-2-hydroxy-2-methylpropanamideC ardarineEnhanced Athlete(GW501516) EndurobolCardarineMass Muscle Makerno imageCardarineTwisted LabsCardarine (GW-501516)Cardarine GW-1516 Brain LabzCardarine GW-1516 Cardarine GW-501516 Medals Research**Cardarine GW-501516 SARMSX**Cardarine GW501515 Pureline NutritionCARDAR1NE {4-[({4-methyl-2-[4-(trifluoromethyl)phe nyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2 -methylphenoxy}acetic acid, OSTAR1NE ((2S)

6 -3-(4-cyanophenoxy)-N-[4-cyano-3-(triflu oro-methyl)phenyl]-2-hydroxy-2-methylpro panamide)Cardarine GW501516 Cratus LabsCardarine {4-[({4-methyl-2-[4-(trifluoromethyl)phe nyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2 -methylphenoxy}acetic acid, OSTAR1NE ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(t rifluoro-methyl)phenyl]-2-hydroxy-2-meth ylpropanamide)Elite GW 501516 Focused Nutrition EuropeGW 501516 Elite LGD 4033 Focused Nutrition EuropeLGD 4033 Elite MK- 677 Focused Nutrition EuropeMK-677 (Ibutamoren)Elite RAD 140 Focused Nutrition EuropeR A D 14 0 Elite SARM StackFocused Nutrition EuropeLDG-4033, Ostarine (MK-2866), GW-501516 Elite SR-9099 Focused Nutrition EuropeSR-9099 Elite YK-11 Focused Nutrition EuropeY K-11 Endura ShredOlympus UKCARDAR1NE {4-[({4-methyl-2-[4-(trifluoromethyl)phe nyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2 -methylphenoxy}acetic acid, OSTAR1NE ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(t rifluoro-methyl)phenyl]-2-hydroxy-2-meth ylpropanamide)EndureKodiak LabsSR9009 EndurobolHardcore FormulationsSelect Androgen Receptor Modulator GW501506 EndurobolSwole LabsCardarine (GS501516)CREATED BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 Product NameDistributor or Manufacturer Ingredients on label/advertising (** denotes research labeling/advertising.

7 Not labeled as a Dietary supplement )Epi-GHPrimeval LabsMK-677 (Ibutamoren)Epica StackLegal PowerLGD-4033 ExpandedBeast Biotech UKLDG-4033, MK-2866, GW-501516 FemavarPlatinum NutraceuticalsGW501516 FierceKodiak LabsRAD140 SARMF olistatin StackLegal PowerMK-2866, MK-677, YK-11GH-ProPlatinum NutraceuticalsMK-677 (Ibutamoren)Ghar1neOlympus UKIbutamoren/MK-677 (R)-1 -(2-methylalanyl-O-Ben-zyl-D-seryl)-1-(m ethylsulfonyl)-1,2-dihydrospiro[in-dole- 3,4 -piperidine]GrizzlyKodiak LabsIbutamoren (MK-677)Growth HormoneEnhanced AthleteMK-677 (Nutrobol/Ibutamoren/(R)-1-(2-methylalan yl-O-ben-zyl-D-seryl)-1-(methylsulfonyl) -1,2dihydrospiro[in-dole-3,4-piperidine] )GW 501516 Peptides Warehouse**GW 50516 All American Peptide**GW ExtremeMass Geneticsno imageGW StaminaSARM Tech{4-[({4-methyl-2-[4-(trifluoromethyl )phenyl]-1,3-thiazol-5-yl}methyl)sulfany l]-2-methylphenoxy}acetic acidGW-15 Dark Label Nutrition (DLN)GW-501516GW-501516 Blue Sky Peptide**GW-501516 IronMag Research**GW-501516 Madison James Research Chem-icals**GW-501516 Maxim Peptide**GW-501516 SARMS1**GW-501516 Transformix Peptides**GW-501516 (Cardarine)Southern SARMs **GW-XTChem-Tek-LabsGW-501516 Ibut AGen MK- 677 Pureline NutritionIbutamoren MK-677 (R)-1 -(2-methylalanyl-O-ben-zyl-D-seryl)-1-(m ethylsulfonyl)-1,2-dihydrospiro[in-dole- 3,4 -piperidine]IbutamorenLandmark ResearchIbutamoren (MK-677)Ibutamoren MK-677 Cratus LabsIbutamoren MK-677 (R)-1 -(2-methylalanyl-O-ben-zyl-D-seryl)-1-(m ethylsulfonyl)-1,2-dihydrospiro[in-dole- 3,4 -piperidine]Ibutamoren MK-677 (cap-sules)Medals Research**CREATED BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 Product NameDistributor or Manufacturer Ingredients on label/advertising (** denotes research labeling/advertising.

8 Not labeled as a Dietary supplement )Ibutamoren MK677 HGHP anther Sports NutritionMK677 (R)1 (2methylalanylObenzylDseryl)1(methylsulf onyl)1,-2dihydrospiro[indole3,4 piperidine]IbutamorinHardcore FormulationsGrowth Hormone Secretagogue Ibutamorin MK-0677 Jacked the RipperMedFit RxS4, GW-501516 KongMedFit RxMK-2866, GW-501516, MK-677, LGD-4033, RAD140L3gendOlympus UK4-((R)-2-((R)-2,2,2-trifluoro-1-hydrox yethyl)pyrrolidin-1-yl) 2-tri-fluoroMethyl)benzonitrileLean Mass ExtremeMass GeneticsOstarine ((S)-3-(4-Cyanophenoxy)-N-(4-cyano-3-tri fluorometh-yl-phenyl)-2-hydroxy-2-methyl propionamideLeviathanBeast Biotech UKMK-2866, S4 AndarineLGDDark Label Nutrition (DLN)LGD-4033 LGD 4033 (Ligandrol)All American Peptide**LGD CompleteSARM Tech4-((R)-2-((R)-2,2,2-trifluoro-1-hydr oxyethyl)pyrrolidin-1-yl)-2-tri-fluoroMe thyl)benzonitrileLGD EliteBlackstone Labs4-((R)-2-((R)-2,2,2-trifluoro-1-hydr oxyethyl)pyrrolidin-1-yl)-2-tri-fluoroMe thyl)benzonitrileLGD MaxPanther Sports Nutrition4-((R)-2-((R)-2,2,2-trifluoro-1 -hydroxyethyl)pyrrolidin-1-yl) 2-tri-fluoroMethyl)benzonitrileLGD-3303 Cratus Labsno imageLGD-3303 Mass Muscle Makerno imageLGD-4033 Madison James Research Chem-icals**LGD-4033 Mass Muscle Makerno imageLGD-4033 Maxim Peptide**LGD-4033 Peptides Warehouse**LGD-4033 Proven Peptidesno imageLGD-4033 SARMS1**LGD-4033 Southern SARMs **LGD-4033 Transformix Peptides**LGD-S4 Animis InternationalLGD, S4 (Andarine)LGD4033 CompleteMuscle Science4-((R)-2-((R)-2,2,2-trifluoro-1-h ydroxyethyl)pyrrolidin-1-yl)-2-tri-fluor oMethyl)benzonitrileLigandrolEnhanced AthleteLGD-4033 (Ligandrol)LigandrolLandmark ResearchLigandrol LGD-4033 Ligandrol Absolute Mass AgentIntel Pharmano label imageLigandrol LGD-4033 Cratus LabsLigandrol 4-((R)-2((R)-2,2,-trifluoro-1-hydroxyeth yl)pyrroli-din-1-yl)-2-triflurormethyl)

9 Benzonitrile CREATED BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 Product NameDistributor or Manufacturer Ingredients on label/advertising (** denotes research labeling/advertising; not labeled as a Dietary supplement )Ligandrol LGD-4033 Hardcore FormulationsSelect Androgen Receptor Modulator LGD-4033 Ligandrol LGD-4033 (cap-sules)Medals Research**Liquid LGD-4033 CEMproducts**Liquid MK-677 CEMproducts**Liquid OstaCEMproducts**Liquid RAD-140 CEMproducts**Liquid S4 CEMproducts**Liquid YK11 CEMproducts**Mass GHOlympus UKLEGEND 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxye thyl)pyr-rolidin-1-yl)-2-trifluoroMethyl )benzonitrile, GHAR1NE (R)-1 -(2-methylalanyl-O-Benzyl-D-seryl)-1-(me thylsulfo-nyl)-1,2-dihydrospiro[indole-3 ,4 -piperidine]Mass Stack ExtremeMass GeneticsOsta MK-2866, LGD4033MK 677 (Ibutamoren)All American Peptide**MK ExtremeSARM Tech(R)-1 -(2-methylalanyl-O-benzyl-D-seryl)-1-(me thylsulfo-nyl)-1,2-dihydrospiro[indole-3 ,4 -piperidine] MK OstarineSARM Tech((2S)-3-(4-cyanophenoxy)-N-[4-cyano- 3-(trifluoromethyl)phenyl]-2-hydroxy-2-m ethylpropanamide) MK-28 Dark Label Nutrition (DLN)

10 MK-2866MK-2866 Peptides Warehouse**MK-2866 Proven Peptidesno imageMK-2866 SARMS1**MK-2866 (Ostarine)Centurion LabzOstarine MK-2866MK-2866 (Ostarine)Madison James Research Chem-icals**MK-2866 (Ostarine)Maxim Peptide**MK- 6 -7 Dark Label Nutrition (DLN)MK- 677MK- 677 Blue Sky Peptide**MK- 677 IronMag Research**MK- 677 Madison James Research Chem-icals**MK- 677 Mass Muscle Makerno imageMK- 677 Maxim Peptide**MK- 677 Peptides Warehouse**MK- 677 Proven Peptidesno imageMK- 677 Transformix Peptides**CREATED BY OPERATION supplement SAFETY FROM THECONSORTIUM FOR HEALTH AND MILITARY PERFORMANCE (CHAMP) e v 112817 Product NameDistributor or Manufacturer Ingredients on label/advertising (** denotes research labeling/advertising; not labeled as a Dietary supplement )MK-677 (Ibutamoren)Southern SARMs **MK2866 OstaMuscle Science((2S)-3-(4-cyanophenoxy)-N-[4-cya no-3-(trifluoromethyl)phenyl]-2-hydroxy- 2-methylpropanamide) MK2866 OstarineMaximum Labs((2S)-3-(4-cyanophenoxy)-N-[4-cyano- 3-(trifluoromethyl)phenyl]-2-hydroxy-2-m ethylpropanamide)MK677 E x tremeMuscle Science(R)-1 -(2-methylalanyl-O-benzyl-D-seryl)-1-(me thylsulfo-nyl)-1,2-dihydrospiro[indole-3 ,4 -piperidine] Monsta CycleMuscle ScienceLGD-4033, S4, MK-677 Muscle ExtremeMass GeneticsLigandrol 4-((R)-2((R)-2,2,-trifluoro-1-hydroxyeth yl)pyrroli-din-1-yl)-2-triflurormethyl)b enzonitrile Mutant YK-11 Enhanced AthleteY K-11 NecroPlasmVicious LabsMK- 677 Next