Scheduling Actions - Alphabetical Order

1 Scheduling Actions - Alphabetical Order -*Scheduled under 21 USC 811(h) **Extension of temporary control NC = Not Controlled SUBSTANCE PROPOSAL PUBLICATION DATE PUBLICATION DATE FEDERAL REGISTER CITATION EFFECTIVE DATE CSA schedule FINAL Order (1-(4-FLUOROBENZYL)-1H-INDOL-3-YL)(2,2,3 ,3-TETRAMETHYLCYCLOPROPYL)METHANONE (FUB-144) * 04-16-19 84 FR 15505 4/16/2019 I (1-(4-FLUOROBENZYL)-1H-INDOL-3-YL)(2,2,3 ,3-TETRAMETHYLCYCLOPROPYL)METHANONE (FUB-144) ** 03-31-21 86 FR 16669 4/16/2021 I (1-(4-FLUOROBENZYL)-1H-INDOL-3-YL)(2,2,3 ,3-TETRAMETHYLCYCLOPROPYL)METHANONE (FUB-144) 04-07-22 87 FR 20318 4/7/2022 I (1-PENTYL-1H-INDOL-3-YL)(2,2,3,3-TETRAME THYLCYCLOPROPYL)METHANONE (UR-144) * 05-16-13 78 FR 28735 5/16/2013 I (1-PENTYL-1H-INDOL-3-YL)(2,2,3,3-TETRAME THYLCYCLOPROPYL)METHANONE (UR-144) ** 05-15-15 80 FR 27854 5/15/2015 I (1-PENTYL-1H-INDOL-3-YL)(2,2,3,3-TETRAME THYLCYCLOPROPYL)METHANONE (UR-144) 05-11-16 81 FR 29142 5/11/2016 I [1-(5-FLUOROPENTYL)-1H-INDAZOL-3-YL](NAP HTHALEN-1-YL)METHANONE (THJ-2201) * 01-30-15 80 FR 5042 1/30/2015 I [1-(5-FLUOROPENTYL)-1H-INDAZOL-3-YL](NAP HTHALEN-1-YL)METHANONE (THJ-2201) 10-16-17 82 FR 47971 10/16/2017 I [1-(5-FLUORO-PENTYL)1H-INDOL-3-YL](2,2,3 ,3-TETRAMETHYLCYCLOPROPYL)METHANONE(5-FL UORO-UR-144, XLR11) * 05-16-13 78 FR 28735 5/16/2013 I [1-(5-FLUORO-PENTYL)]

2 1H-INDOL-3-YL](2,2,3,3-TETRAMETHYLCYCLOP ROPYL)METHANONE(5-FLUORO-UR-144, XLR11) ** 05-15-15 80 FR 27854 5/5/2015 I [1-(5-FLUORO-PENTYL)1H-INDOL-3-YL](2,2,3 ,3-TETRAMETHYLCYCLOPROPYL)METHANONE(5-FL UORO-UR-144, XLR11) 05-11-16 81 FR 29142 5/11/2016 I [123I]IOFLUPANE 06-03-15 09-11-15 80 FR 54715 9/11/2015 II --> NC [18F]FP-CIT 11-04-21 11-21-22 87 FR 70715 12/21/2022 II --> NC 1-(1-(1-(4-BROMOPHENYL)ETHYL)PIPERIDIN-4 -YL)-1,3-DIHYDRO-2H-BENZO[D]IMIDAZOL-2-O NE (BRORPHINE) * 03-01-21 86 FR 11862 3/1/2021 I 1-(1-(1-(4-BROMOPHENYL)ETHYL)PIPERIDIN-4 -YL)-1,3-DIHYDRO-2H-BENZO[D]IMIDAZOL-2-O NE (BRORPHINE) 03-06-23 88 FR 13692 4/5/2023 I 1-(1,3-BENZODIOXOL-5-YL)-2-(ETHYLAMINO)- PENTAN-1-ONE (N-ETHYLPENTYLONE, EPHYLONE) * 08-31-18 83 FR 44474 8/31/2018 I 1-(1,3-BENZODIOXOL-5-YL)-2-(ETHYLAMINO)- PENTAN-1-ONE (N-ETHYLPENTYLONE, EPHYLONE) ** 08-27-20 85 FR 52915 8/31/2020 I 1-(1,3-BENZODIOXOL-5-YL)-2-(ETHYLAMINO)- PENTAN-1-ONE (N-ETHYLPENTYLONE, EPHYLONE) 06-14-21 86 FR 31427 6/14/2021 I 1-(3-TRIFLUOROMETHYLPHENYL)PIPERAZINE (TFMPP) * 09-20-02 67 FR 59161 9/20/2002 I 1-(3-TRIFLUOROMETHYLPHENYL)PIPERAZINE (TFMPP) ** 09-10-03 68 FR 53289 9/20/2003 I 1-(3-TRIFLUOROMETHYLPHENYL)PIPERAZINE (TFMPP) 09-08-03 03-18-04 69 FR 12794 3/19/2004 I --> NC 1-(4-CYANOBUTYL)-N-(2-PHENYLPROPAN-2-YL) -1H-INDAZOLE-3-CARBOXAMIDE (4-CN-CUMYL-BUTINACA)

3 * 07-10-18 83 FR 31877 7/10/2018 I 1-(4-CYANOBUTYL)-N-(2-PHENYLPROPAN-2-YL) -1H-INDAZOLE-3-CARBOXAMIDE (4-CN-CUMYL-BUTINACA) ** 07-13-20 85 FR 42296 7/10/2020 I Page 1 of 18 Scheduling Actions - Alphabetical Order 14-Dec-23 *Scheduled under 21 USC 811(h) **Extension of temporary control NC = Not Controlled SUBSTANCE PROPOSAL PUBLICATION DATE PUBLICATION DATE FEDERAL REGISTER CITATION EFFECTIVE DATE CSA schedule FINAL Order 1-(4-CYANOBUTYL)-N-(2-PHENYLPROPAN-2-YL) -1H-INDAZOLE-3-CARBOXAMIDE (4-CN-CUMYL-BUTINACA) 06-10-21 86 FR 30775 6/10/2021 I 1-(5-FLUOROPENTYL)-N-(2-PHENYLPROPAN-2-Y L)-1H-INDAZOLE-3-CARBOXAMIDE (5F-CUMYL-PINACA; SGT-25) * 04-16-19 84 FR 15505 4/16/2019 I 1-(5-FLUOROPENTYL)-N-(2-PHENYLPROPAN-2-Y L)-1H-INDAZOLE-3-CARBOXAMIDE (5F-CUMYL-PINACA; SGT-25) ** 03-31-21 86 FR 16669 4/16/2021 I 1-(5-FLUOROPENTYL)-N-(2-PHENYLPROPAN-2-Y L)-1H-INDAZOLE-3-CARBOXAMIDE (5F-CUMYL-PINACA.)

4 SGT-25) 04-07-22 87 FR 20318 4/7/2022 I 1-(5-FLUOROPENTYL)-N-(2-PHENYLPROPAN-2-Y L)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXAMI DE (5F-CUMYL-P7 AICA) * 07-10-18 83 FR 31877 7/10/2018 I 1-(5-FLUOROPENTYL)-N-(2-PHENYLPROPAN-2-Y L)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXAMI DE (5F-CUMYL-P7 AICA) ** 07-13-20 85 FR 42296 7/10/2020 I 1-(5-FLUOROPENTYL)-N-(2-PHENYLPROPAN-2-Y L)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXAMI DE (5F-CUMYL-P7 AICA) 06-10-21 86 FR 30775 6/10/2021 I 1-[1-(2-THIENYL)CYCLOHEXYL]PYRROLIDINE 03-20-89 07-06-89 54 FR 28414 7/6/1989 I 19-NOR-4,9(10)-ANDROSTADIENEDIONE (estra-4,9(10)-diene-3,17-dione) 04-25-08 12-04-09 74 FR 63603 1/4/2010 III 2-(2-(4-BUTOXYBENZYL)-5-NITRO-1H-BENZIMI DAZOL-1-YL)-N,N-DIETHYLETHAN-1-AMINE (BUTONITAZENE) * 04-12-22 87 FR 21556 4/12/2022 I 2-(2-(4-ETHOXYBENZYL)-1H-BENZIMIDAZOL-1- YL)-N,N-DIETHYLETHAN-1-AMINE (ETODESNITAZENE.

5 ETAZENE) * 04-12-22 87 FR 21556 4/12/2022 I 2-(4-BROMO-2,5-DIMETHOXYPHENYL)-N-(2-MET HOXYBENZYL)ETHANAMINE (25B-NBOMe) * 11-15-13 78 FR 68716 11/15/2013 I 2-(4-CHLORO-2,5-DIMETHOXYPHENYL)-N-(2-ME THOXYBENZYL)ETHANAMINE (25C-NBOMe) * 11-15-13 78 FR 68716 11/15/2013 I 2-(4-ETHOXYBENZYL)-5-NITRO-1-(2-(PYRROLI DIN-1-YL)ETHYL)-1H-BENZIMIDAZOLE (N-PYRROLIDINO ETONITAZENE) * 04-12-22 87 FR 21556 4/12/2022 I 2-(4-IODO-2,5-DIMETHOXYPHENYL)-N-(2-METH OXYBENZYL) ETHANAMINE (25I-NBOMe) * 11-15-13 78 FR 68716 11/15/2013 I 2,5-DIMETHOXY-4-(n)-PROPYLTHIOPHENETHYLA MINE (2C-T-7) * 09-20-02 67 FR 59163 9/20/2002 I 2,5-DIMETHOXY-4-(n)-PROPYLTHIOPHENETHYLA MINE (2C-T-7) ** 09-10-03 68 FR 53289 9/20/2003 I 2,5-DIMETHOXY-4-(n)-PROPYLTHIOPHENETHYLA MINE (2C-T-7) 09-08-03 03-18-04 69 FR 12794 3/18/2004 I 2,5-DIMETHOXY-4-CHLOROAMPHETAMINE (DOC) 04-11-22 04-11-22 87 FR 21069 I 2,5-DIMETHOXY-4-CHLOROAMPHETAMINE (DOC) 04-11-22 08-29-22 87 FR 52712 I Withdrew 2022 proposed rule 2,5-DIMETHOXY-4-ETHYLAMPHETAMINE (DOET) 10-30-87 01-14-93 58 FR 4316 2/16/1993 I 2,5-DIMETHOXY-4-IODOAMPHETAMINE (DOI) 04-11-22 04-11-22 87 FR 21069 I 2,5-DIMETHOXY-4-IODOAMPHETAMINE (DOI) 04-11-22 08-29-22 87 FR 52712 I Withdrew 2022 proposed rule 2,5-DIMETHOXYAMPHETAMINE (DMA)

6 05-31-73 09-21-73 38 FR 26447 9/21/1973 I Page 2 of 18 Scheduling Actions - Alphabetical Order 14-Dec-23 *Scheduled under 21 USC 811(h) **Extension of temporary control NC = Not Controlled SUBSTANCE PROPOSAL PUBLICATION DATE PUBLICATION DATE FEDERAL REGISTER CITATION EFFECTIVE DATE CSA schedule FINAL Order 2',5'-DIMETHOXYFENTANYL (N-(1-(2,5-DIMETHOXYPHENETHYL)PIPERIDINE -4-YL)-N-PHENYLPROPIONAMIDE) 12-07-23 88 FR 85104 12/7/2023 I 2'-FLUORO ORTHO-FLUOROFENTANYL 04-27-21 86 FR 22113 4/27/2021 I 3,4-DICHLORO-N-[(1-DIMETHYLAMINO)CYCLOHE XYLMETHYL]BENZAMIDE) (AH-7921) 04-14-16 81 FR 22023 5/15/2016 I 3,4-DICHLORO-N-[2-(DIMETHYLAMINO)CYCLOHE XYL]-N-METHYLBENZAMIDE (U-47700) * 11-14-16 81 FR 79389 11/14/2016 I 3,4-DICHLORO-N-[2-(DIMETHYLAMINO)CYCLOHE XYL]-N-METHYLBENZAMIDE (U-47700) 04-20-18 83 FR 17486 4/20/2018 I 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE; MDEA) * 10-15-87 52 FR 38225 10/15/1987 I 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE; MDEA) ** 10-13-88 53 FR 40061 10/13/1988 I 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE.

7 MDEA) 10-14-88 04-13-89 54 FR 14797 4/13/1989 I 3,4-METHYLENEDIOXY-N-METHYLCATHINONE (METHYLONE) * 10-21-11 76 FR 65371 10/21/2011 I 3,4-METHYLENEDIOXY-N-METHYLCATHINONE (METHYLONE) 10-21-11 04-12-13 78 FR 21818 4/12/2013 I 3,4-METHYLENEDIOXYPYROVALERONE (MDPV) * 10-21-11 76 FR 65371 10/21/2011 I 3-ALPHA-HYDROXY-3-BETA-METHYL-5-ALPHA-PR EGNAN-20-ONE (GANAXOLONE) 06-01-22 87 FR 32991 6/1/2022 V 3-FLUORO-N-METHYLCATHINONE (3-FMC) * 03-07-14 79 FR 12938 3/7/2014 I 3-FLUORO-N-METHYLCATHINONE (3-FMC) ** 03-04-16 81 FR 11429 3/4/2016 I 3-FLUORO-N-METHYLCATHINONE (3-FMC) 03-04-16 03-01-17 82 FR 12171 3/1/2017 I 3-FURANYL FENTANYL (N-(1-PHENTHYLPIPERIDIN-4-YL)-N-PHENYLFU RAN-3-CARBOXAMIDE) 12-07-23 88 FR 85104 12/7/2023 I 3-METHYLFENTANYL * 03-25-85 50 FR 11690 4/25/1985 I 3-METHYLFENTANYL ** 04-24-86 51 FR 15474 4/25/1986 I 3-METHYLFENTANYL 04-24-86 09-22-86 51 FR 33592 9/22/1986 I 3-METHYLTHIOFENTANYL * 10-29-85 50 FR 43698 11/29/1985 I 3-METHYLTHIOFENTANYL ** 11-26-86 51 FR 42834 11/29/1986 I 3-METHYLTHIOFENTANYL 11-28-86 05-29-87 52 FR 20070 5/29/1987 I 3-MMC (2-(METHYLAMINO)-1-(3-METHYLPHENYL)PROPA N-1-ONE) 12-13-23 88 FR 86266 12/13/2023 I 4-(2-CHLOROPHENYL)-2-ETHYL-9-METHYL-6H-T HIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]D IAZEPINE (ETIZOLAM) * 07-26-23 88 FR 48112 7/26/2023 I 4,4 -DIMETHYLAMINOREX (4,4 -DMAR.

8 4,5-DIHYDRO-4- METHYL-5-(4-METHYLPHENYL)-2-OXAZOLAMINE) 04-07-20 08-12-21 86 FR 44270 9/13/2021 I 4 -METHYL-ALPHA-PYRROLIDINOHEXIOPHENONE (MPHP) * 07-18-19 84 FR 34291 7/18/2019 I 4 -METHYL-ALPHA-PYRROLIDINOHEXIOPHENONE (MPHP) ** 07-18-21 86 FR 37672 7/18/2021 I 4 -METHYL-ALPHA-PYRROLIDINOHEXIOPHENONE (MPHP) 06-01-22 87 FR 32996 6/1/2022 I 4-ANILINO-N-PHENETHYL-4-PIPERIDINE (ANPP) 04-09-08 06-29-10 75 FR 37296 8/30/2010 II 4-BROMO-2,5-DIMETHOXYAMPHETAMINE 07-02-73 09-21-73 38 FR 26447 9/21/1973 I 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE * 01-06-94 59 FR 00671 1/6/1994 I Page 3 of 18 Scheduling Actions - Alphabetical Order 14-Dec-23 *Scheduled under 21 USC 811(h) **Extension of temporary control NC = Not Controlled SUBSTANCE PROPOSAL PUBLICATION DATE PUBLICATION DATE FEDERAL REGISTER CITATION EFFECTIVE DATE CSA schedule FINAL Order 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE ** 12-21-94 59 FR 65710 1/6/1995 I 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE 12-20-94 06-02-95 60 FR 28718 6/2/1995 I 4'-CHLORO-ALPHA-PYRROLIDINOVALEROPHENONE (4-CHLORO-A-PVP) * 07-18-19 84 FR 34291 7/18/2019 I 4'-CHLORO-ALPHA-PYRROLIDINOVALEROPHENONE (4-CHLORO-A-PVP) ** 07-18-21 86 FR 37672 7/18/2021 I 4'-CHLORO-ALPHA-PYRROLIDINOVALEROPHENONE (4-CHLORO-A-PVP) 06-01-22 87 FR 32996 6/1/2022 I 4-FLUORO-N-METHYLCATHINONE (4-FMC)

9 * 03-07-14 79 FR 12938 3/7/2014 I 4-FLUORO-N-METHYLCATHINONE (4-FMC) ** 03-04-16 81 FR 11429 3/4/2016 I 4-FLUORO-N-METHYLCATHINONE (4-FMC) 03-04-16 03-01-17 82 FR 12171 3/1/2017 I 4F-MDMB-BUTICA (METHYL 2-[[1-(4-FLUOROBUTYL)INDOLE-3-CARBONYL]A MINO]-3,3-DIMETHYL-BUTANOATE) * 12-12-23 88 FR 86040 12/12/2023 I 4-HYDROXY-N,N-DIISOPROPYLTRYPTAMINE (4-OH-DiPT) 01-14-22 01-14-22 87 FR 2376 I 4-HYDROXY-N,N-DIISOPROPYLTRYPTAMINE (4-OH-DiPT) 01-14-22 07-27-22 87 FR 45076 I Withdrew 2022 proposed rule 4-METHOXYAMPHETAMINE (PMA) 07-02-73 09-21-73 38 FR 26447 9/21/1973 I 4'-METHYL ACETYL FENTANYL 04-27-21 86 FR 22113 4/27/2021 I 4-METHYL-ALPHA-ETHYLAMINOPENTIOPHENONE (4-MEAP) * 07-18-19 84 FR 34291 7/18/2019 I 4-METHYL-ALPHA-ETHYLAMINOPENTIOPHENONE (4-MEAP) ** 07-18-21 86 FR 37672 7/18/2021 I