脂肪の代謝とその調節 - sci.u-hyogo.ac.jp

1 (1) (-OH) R -COOH R DHA

2 24 21 53 (2) (3) 120 m (1 m = 1/1000 mm)

3 1 (4) Protein Kinase A PKA PKA Hormone-Sensitive Lipase; HSL 1970 (1) A. PKA HSL PKA B.

4 20 AB HSL HSL HSL HSL HSL HSL (2) (3,4) (5)

5 HSL HSL 1 HSL CGI-58 CGI-58 (6) CGI-58 (7,8) CGI-58 Adipocyte Triglyceride Lipase; ATGL ATGL (9) HSL HSL ATGL CGI-58 (10) ATGL HSL (MGL) CGI-58 ATGL ATGL HSL CGI-58 CGI-58 ATGL CGI-58 HSL CGI-58 ATGL HSL ATGL HSL (Monoglyceride Lipase.)

6 MGL) CGI-58 ATGL HSL HSL (1)

7 (2) ADRP Tip47 (Perilipin) PAT S3-12 PAT PAT (10) PAT PAT1 11 S3-12 PAT1 PAT1 ADRP MLDP (11)

8 S3-12 ADRP TiP47 MLDP Myocardial Lipid Droplet Protein MLDP PAT PAT PAT MLDP MLDP MLDP MLDP MLDP HSL 1970 1990 PAT ATGL CGI-58 1.

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