デフェラシロクスによる - shino-test.co.jp

1 (Fe) (UIBC) DFX Fe UIBC deferasirox DFX UIBC DFX Fe Fe UIBC Fe Fe,UIBC Free DFX UIBC DFX Fe Fe UIBC Fe,UIBC Fe UIBC 12 2011 S145 deferasirox DFX Content M)FeUIBC TIBC073 199 0 (%)272 0 (%)6073271 136%344 126%12074343 172%417 153%18074410 206%484 178%24073461 232%534 196%30073512 257%585 215%( g/dL)( g/dL)

2 FreeDFX Fe UIBC DFX 01002003004005006000 50 100 150 200 250 300 Free M) g/dL)FeUIBC Fe:35 M DFX:70 M 142( g/dL)( g/dL)Fe (200 g/dL) DFX DFX-Fe Fe Fe Fe DFX-Fe UIBC DFX-Fe Fe DFX-Fe DFX-Fe Fe DFX-Fe ( g/dL) ( g/dL) Sample Reagent-IReagent-II 5min10min pH4 Fe3+ Fe2+ Fe2+ NitrosoPSAPApo TfHolo Tf Free DFX DFX-Fe Free DFX DFX-Fe Tf-Fe DFX-Fe DFX Sample Reagent-Reagent-II 5min10min pH4 Fe3+ Fe2+ Fe2+ NitrosoPSAPS ample Reagent-Reagent-II 0min5min10min pH4 Fe3+ Fe2+ Fe2+ NitrosoPSAPApo TfHolo TfApo TfHolo Tf DFX-Fe Free DFX DFX-Fe Tf-Fe DFX-Fe SampleReagent-IReagent-II Apo-Tf ApoTf Fe3+ Fe2+ NitrosoPSAP Apo TfHolo Tf Fe(III)

3 ApoT free DFX UIBC UIBC DFX Free DFX Free DFX DFX-Fe DFX-Fe SampleReagent-Reagent-II Apo-Tf ApoTf Fe3+ Fe2+ NitrosoPSAP Apo TfHolo Tf Fe(III) apoT free DFX UIBC UIBC DFX -600nm Nitroso-PSAP DFX-Fe Nitroso-PSAP UIBC