Transcription of Steroid Pathways - Mayo Medical Laboratories
1 09/2013 mayo Foundation for Medical Education and Research (MFMER). All rights reserved. mayo , mayo Medical Laboratories and the triple-shield mayo logo are trademarks and/or service marks of PathwaysMineral-corticoidsGluco-corticoi dsSex SteroidsCortisolStAR (STARD 1) and 20,22 Desmolase (CYP11A1)Corticosterone18-Deoxycorticost eroneAldosteroneCholesterolPregnenoloneP rogesterone11 -Hydroxylase 1 (CYP11B1)or (less active ) CYP11B211 -Hydroxylase 2 ( CY P11B 2) o r CY P11B1CY P11B 2CY P11B 211-Deoxycorticosterone17-Hydroxyprogest erone3 Hydroxysteroid Dehydrogenase (3 -HSD, HSD3B2)17-Hydroxypregenenolone11-Deoxyco rtisolDehydroepiandrosteroneAndrostenedi oneEstroneAndrostenediolTestosteroneDihy drotestosteroneEstradiol17 -Hydroxylase (CYP17A1)17, 2 0 - Ly a s e(CYP17A1)17 -HSD(HSD17B3)5 -Reductase(SRD5A1)Aromatase (CYP19A1)21-Hydroxylase (CYP21A2)
