Transcription of Tスポット .TBについて - jata.or.jp
1 1 2013 BCG BCG 2 ESAT-6, CFP-10 Interferon Gamma Release Assay IGRA BCG 2000 TB QFT T .TB T . TB T Spot IGRA QFT ELISA T Spot ESAT-6 CFP-10 SPOT SPOT 24 10 9 11 13 QFT - 630 144 1 - 1.
2 6ml 18 25 C 2. PBMC T .TB 3. IFN- PBMC A :ESAT-6 B : CFP-10 16 20 4. 5. IFN- T T-Cell Xtend 32 T-Cell Xtend PBMC 32 T-Cell Xtend 8 1. 1 ESAT-6 2 CFP-10 1 A ESAT-6 - 2 B CFP-10 - 2.
3 1 1 CFP104 5 ESAT-64 5 1 2 6 1 2 5 1 2 5 7 CFP104 5 ESAT-64 5 82013/01/05 15:09:511 2013 8 4 10 20 2 E S AT- 6 CFP-10 4 5-7 8 2 Nil Mitogen 10 8 10 5,6,7 10 4 10 10 5 20 Nil: : Mitogen.
4 QFT QFT T Spot 1. 2. 3. HIV LTBI 4. 1. ESAT-6 CFP10 2 BCG 2. QFT IGRA 8-10 3.
5 IGRA QFT QFT 1 QFT 2 QFT, T Spot T Spot 3 6mL QFT 1 Pai M, Joshi R, Dogra S et al. Serial testing of health care workers for tuberculosis using interferon assay. Am J Respire Crit Care Med 2006; 174: 349- 3552 Higuchi K, Sekiya Y, Igari H et al.
6 Comparison of specificities between two interferon-gamma release assays in Japan. Int J Tuberc Lung Dis 2012; 16:1190 11923 KomiyaK, Ariga H, Nagai H et al. Impact of Peripheral Lymphocyte Count on the Sensitivity of 2 IFN-Y Release Assays, QFT-G and ELISPOT, in Patients with Pulmonary Tuberculosis. Inter Med2010; 49: 92013/01/05 15:09:51
