The Festival of Genomics & Biodata • Day 1 Agenda ...

1 TIME ESTTIME GMT04:0009:0004:3009:3005:0010:0005:3010 :3005:4010:4005:5010:50 Track 1 Track 2 Track 3 Track 4 Track 5 Track 606:0011:00 Applications of RNA-seq for infectious disease researchJose Afonso Guerra-Assuncao, Research Associate, UCLC ancer evolution, immune evasion and metastasisCharles Swanton, Group Leader, Francis Crick InstituteOrganoids and single cell RNA sequencing to study human brain diseasesMichela Deleidi, Assistant Professor, Department of Neurodegenerative Diseases, University of T bingenGenomic loci susceptible to systematic sequencing bias in clinical whole genomesDennis Wang, Head of Bioinformatics, University of SheffieldHow Genomics is helping the NHS to revolutionise cancer careProfessor Sandi Deans, Deputy Director, Laboratory & Scientific, Genomics Unit.

2 NHS England and NHS ImprovementOligonucleotide therapy development for patients with unique genetic mutations: considerations and perspectivesAnnemieke Aartsma-Rus, Professor Human Genetics, Leiden University06:3011:30A simple web-based tool to integrate RNA-seq gene expression data with qPCR and digital PCR verification Verena SchrammAssociate Director, Global Product Management, QIAGEN MEDUSA: a platform for Genomic interrogation of response to therapy of mesothelioma Dean A.

3 Fennell, PhD FRCPP rofessor and Consultant in Thoracic Medical Oncology and Director, Mesothelioma Research Programme,University of LeicesterSponsored by Novogene10x Genomics : Access the full richness of biological complexity with single cell and spatial multiomics Stephen Hague, Senior Science and Technology Advisor, 10x GenomicsUnlocking the power of genomic research with IQVIA bioinformatic capabilitiesJoanne Hackett, Head of Genomic and Precision Medicine, IQVIAD avid Latto, Associate Director, Science Liaison - Genomics , IQVIAI ntegrating Genomics across the NHS s nursing and midwifery workforce: an all-England approachSarah Armstrong-Klein, Senior Improvement Advisor, Nursing and Midwifery, Genomics Unit, NHS England and NHS Improvement Dr.

4 Emma Tonkin, Co-lead, National Nursing & Midwifery Genomics Transformation Project, NHS North-East and Yorkshire Genomics Medicine Service AlliancePrecision Medicine beyond OncologyMaria Orr, Head of Precision Medicine, Biopharmaceuticals, AstraZeneca07:0012:00 Spatial and temporal RNA-sequencingSam Rodriques, Group Leader, Francis Crick InstituteMolecular stratification onto a national lung cancer precision medicine trial: infrastructure, delivery and challengesDonald White, Programme Manager, Precision Medicine, Cancer Research UKApplication of single-cell multi-omics to discover cancer cell-specific drug targets in blood cancer Bethan Psaila, University of OxfordNovel informatic approaches for genotype-to-phenotype analyses of medical genomic dataSarah Ennis, Professor, University of SouthamptonA NICE approach to assess the next generation of genomic technologiesSarah Byron, Programme Director for Devices, Diagnostics and Digital, NICE Human Genomics to fuel drug discovery effortsVincent Mooser, Canada Excellence Research Chair in Genomic Medicine, McGill University07:3012:3007:4512:4508.

5 0013:0008:1513:15 Track 1 Track 2 Track 3 Track 4 Track 5 Track 608:3013:30 Translating germline cancer Genomics into precision prevention of cancerClare Turnbull, Professor of Translational Cancer Genetics, ICRE arly detection of Barrett s oesophagus and oesophageal adenocarcinoma using Oxford Nanopore long-read sequencing Neus Masque-Soler, Senior Postdoctoral Fellow, University of CambridgeAlvin Ng, Computational Postdoctoral Scientist, Fitzgerald Lab, University of CambridgeExploring tissue architecture using spatial transcriptomicsItai Yanai, Director of the Institute for Computational Medicine, NYU Langone HealthUsing Genomics to prevent coronary artery disease Akl C.

6 Fahed, MD, MPH Interventional Cardiologist, Massachusetts General Hospital, Instructor in Medicine, Harvard Medical School and Affiliated Scientist, Broad Institute of MIT and HarvardAstraZeneca's 2 Million Genomes Initiative and the relevance of FAIR data principles in pharmaceutical R&DChuang Kee Ong, Associate Director, Information Architect Lead, AstraZeneca09:0014:00 Liquid biopsy technology and the future of cancer careMark Li, CEO, Resolution Bioscience - part of AgilentDeveloping an end-to-end solution for cancer whole-genome sequencing with PromethIONGreg Elgar, Director of Sequencing, Genomics EnglandSponsored by Oxford NanoporeHarnessing full-length scRNA-seq to empower biomarker discoveryMario Avarello, Business development Manager Automation, Takara Bio EuropeScreening for actionable variants in an unselected healthcare system cohort: The Geisinger experience - Adam Buchanen, Director of Genomic Medicine Institute, Geisinger The FAIR plus project.

7 FAIR put into practiceJolanda Strubel, Data Manager, The HyveSponsored by The Hyve09:3014:30 Molecular diagnostics and the NHSE Long Term Plan for CancerPeter Johnson, National Clinical Director for Cancer, NHS EnglandUsing nanopore sequencing for GBA in Parkinson's diseaseChristos Proukakis, Professor of Neurology and Neurogenetics, UCL Queen Square Institute of NeurologyMapping human tissue architecture using spatial genomicsOmer Bayrakter, Group Leader, Wellcome SangerHow Genomics England Solves its Data Storage Challenges - Fireside ChatPete Sinden, CIO, Genomics England Liran Zvibel, CEO, WEKAS ponsored by WEKAH uman Genomics in a changing worldSusan Fairley, Chief Standards Officer.

8 GA4 GhCreating a FAIR and equitable data ecosystem for biomedicineSusan Gregurick, Associate Director for Data Science, National Institutes of Health10:0015:0010:1015:1015:20 Track 1 Track 2 Track 3 Track 4 Track 5 Track 610:3015:30 Exploring the tissue landscape with multimodal molecular toolsJoakim Lundeberg, Professor, SciLifeLabGenomics led precision medicine and healthcare- where is the evidenceDhavendra Kumar, Clinical Professor, Barts & The London School of Medicine and Queen Mary University of London. Bench to Bytes to Bedside: Converting genomic data into healthcare toolsSerena Nik-Zainal, NIHR Research Professor, University of CambridgeBuilding an ecosystem of Trusted Research EnvironmentsTim Hubbard, Head of Genome Analysis, Genomics EnglandGenomics for Personalised Medicine in childhood Acute Lymphoblastic Leukaemia John Moppett, Consultant Paediatric Haematologist, University Hospitals Bristol, NHS FoundationMoving beyond proofs of concept for biomedical AIPaul Agapow, Statistics and Data Science Innovation Hub, GSK11:0016:00 NanoString spatial biology roadmap.

9 Whole transcriptome digital spatial profiling and subcellular multi-omic spatial molecular imagingTony Zucca, Technical Sales Specialist, NanoString TechnologiesDavid Henderson, Director, Biostatistics, NanoString TechnologiesHiFi Sequencing: See What You ve Been MissingNeil Ward, Vice President and General Manager, PacBio EMEAThe clinical significance of missense variants in breast cancer susceptibility genes results from the BRIDGES' project Peter Devilee, Professor in Tumour Genetics, Leiden UniversitySponsored by Sophia GeneticsAWS Cloud in GenomicsKira Levy, Head of Healthcare UK, Amazon Web ServicesThe fine art of dPCR Decrypting the MIQE GuidelinesAfif Abdel Nour, Professional Customer Solution Manager dPCR, QIAGENB reakthrough AI finds more patients, including those who are undiagnosed and miscoded, and automatically generates clinical narratives from tables.

10 In a federated privacy preserving mannerJingqing Zhang, Head of AI, Pangaea Data11:3016:30 Application of single cell and spatial transcriptomics in Alzheimer s disease research Wei-Ting Chen, Staff Scientist, KU LeuvenPanel discussion: Combining long and short read sequencingAndrew Beggs, Professor, University of BirminghamMike Hubank, Director of Clinical Genomics , Royal Marsden Hospital & Professor of Translational Genomics , ICRMatt Loose, Professor of Developmental and Computational Biology, University of NottinghamDeploying cancer data to address real world challenges: Time To Act!Mark Lawler, Professor of Digital Health, Queen's University Belfast and Scientific Director, DATA-CAN, the UK's Health Data Research Hub for CancerWhat do future healthcare databanks look like?