The next generation in Complete Urinalysis.

1 next generation inCompleteiRICELL Comprehensive Urine Testing Solutions to Meet Today s ChallengesIris image technology is recognized as the gold standard in automated urine microscopy. Since its launch in 2004, 2,200 iQ 200 Automated Urine Microscopy Systems have been placed in laboratories worldwide. With an expanded focus toward urine chemistry, Iris Diagnostics introduces the iRICELL family of integrated urinalysis workcells, developed manufactured and distrib-uted by the leader in automated urine microscopy. The iRICELL Solution is consistent with LEAN principles and provides a positive return on your investment by: streamlining the manual processes in urinalysis departments providing comprehensive screening for UTI protecting CMS reimbursement addressing productivity challenges without increasing staff improves training and maintaining high levels of staffing competency FTE productivity increased 2 to 4 hours per day depending on workload.

2 * * Based upon Iris Diagnostics sponsored clinical evaluations. Data available by request. workcellPERFORMANCE Proven Technology Providing Quality Results State of the art digital images and patented auto-particle recognition (APR ) software provide the most extensive and accurate quantification of urine particles Rigorously tested and accurate urine chemistry assays Utilization of ascorbic acid detection to prevent potential interference with key chemistry assays UTI evaluation supported by a comprehensive set of microscopy and chemistry indicatorsPRODUCTIVITY Streamlined Processes and Faster TAT The iRICELL consolidated Workcells provide walk away operation, high throughput capabilities and customizable microscopy algorithms Supports LEAN workflow principles by consolidating multiple manual urine microscopy processes and accepting one-piece flow operation using barcoded urine collection tubes VALUE Return on Investment UTI screening reduces overall laboratory costs and supports reimbursement requirements iRICELL absorbs increases in workload without investing in additional personnel Automation allows technologists to multi-task in the laboratory reducing overtime Quality results support better patient managementApply the Benefits of Automated Workcells to the urinalysis DepartmentAutomating urinalysis will increase efficiency and

3 Allow highly skilled technologists to manage multiple tasks, simultaneously providing increased efficiency in other Workcells Efficient, completely automated solutions for a labor- intensive workstation, regardless of the daily volume of samples analyzed. iRICELL3000 Combines the iQ 200 SPRINT automated microscopy system with the iChem VELOCITY automated urine Chemistry system. This high volume system meets the workload requirements of high volume the iQ 200 ELITE automated microscopy system with the iChemVELOCITY automated chemistry system. This capable system meets the workload requirements of medium to high volume urinalysis the iQ 200 SELECT automated urine microscopy system with the iChem 100 semi-automated urine chemistry system.

4 This easy-to-use system meets the workload require-ments for small 3000 210 Chemistry & 101 Microscopic Samples / hour iRICELL 2000 210 Chemistry & 70 Microscopic Samples / hour iRICELL 1000 210 Chemistry & 40 Microscopic Samples / hour i RICELL Complete urinalysis WorkCellsiQ200 Series Time Tested PerformanceThe iQ200 is the most popular automated microscopy instrument in North America. Thirteen of the top 19 hos-pitals* utilize the iQ200 system in their laboratories. The iQ200 family of systems is designed to meet all laboratory workloads. Manual microscopy is virtually eliminated with: on-screen verification of digital images streamlined workflow with auto release capabilities to the LIS dramatically improved CV s and reduced errors * Based upon the 2008 US News and World Report Best Hospital Honor Roll microscopyPERFORMANCE Proven Technology Providing Quality Results Proprietary software auto-classifies and quantifies 12 urine particles and provides further sub-classification of 27 particles Images document urine particle morphology Sample analysis is comprehensive, based upon 500 total digital images Standardized automation provides objective.

5 Reproducible results PRODUCTIVITY Streamlined Processes and Faster TAT Microscopy test automatically triggered by user-defined chemistry gating algorithm Comprehensive, customized reports include an operator audit trail Auto-release of results to the LIS based on customized parameters Urine and Body Fluids can be analyzed in the same runVALUE Return on Investment Archived images can be stored for patient monitoring and technologist training purposes with 10,000 samples stored on board Specimen contamination is minimized by reduced sample handling Reduced false negatives for WBC s and RBC s, compared to manual methodology, may improve patient careAuto-classifies and quantifies!Transitional Epithelial Cells (TREP) #1 These images are found in NSE and operator must sub-classify the images and account for any found in few transitional epithelial cells are normal.

6 Increased numbers may be seenwith urinary tract infection. Sheets may be seen after instrument procedures likecatheterization. Sheets seen in the absence of an instrument procedure requireinvestigation as they may indicate a pathological process. C26704_Inside_PPIT 502/12/07 9:09:57 AMTransitional Epithelial CellsBacteria Bacteria may be seen as large rods or as chains of rods or cocci. Bacteriamay also be visualized in the background of other images, especially WBC, WBCC,Mucus and Squamous Epithelial Cells. Bacteria, especially in the absence of WBC,may also be the result of contamination. Note the clump of bacteria, probablymixed in mucus. Bacteria ClumpC26704_Inside_PPIT 172/12/07 9:08:25 AMBacteria Clump* Source; 2007 Boston Biomedical Consultants, Inc.

7 Microscopy Systems Market SERIES of systems are designed for all volume workloads, short turnaround time and results standardization. The iQ200 system is preferred by more US laboratories* as it virtually eliminates manual microscopy. Effortless operation, just load samples, press START and walkaway Workload management iQ 200 SPRINT The fastest automated system on the market, meeting high volume productivity and workload requirements 101 Microscopic Samples / hour iQ 200 ELITE Manages medium to high volume workload 70 Microscopic Samples / hour iQ 200 SELECT Perfect for low volume workload 40 Microscopic Samples / houriQ200 SERIESU rine Microscopy Systems Cellular CastsRed Blood Cells (RBC)Granular CastsYeast Yeast are common contaminants of urine.

8 A true yeast infection willgenerally be accompanied by a significant concentration of leukocytes. Yeast aredistinguishable from erythrocytes (RBC) by their oval shape and thick cell most common forms are budding and pseudohyphae. If yeast are seen, theoperator must account for any images found in UNCL. C26704_Inside_PPIT 202/12/07 9:08:31 AMGranular Casts These casts may be found in the unclassified cast (UNCC) andUNCL category. They must be sub-classified by the operator. Mucus and UNCL must also be reviewed for the presence of other types of casts. Granular castsmay be high or low contrast and high or moderate texture particles. They have thesame size and shape characteristics as Hyaline casts do. Granular casts indicaterenal disease.

9 C26704_Inside_PPIT 252/12/07 9:08:45 AMCalcium Oxylate CrystalsRenal Epithelial CellsYeastWhite Blood Cell Clumps (WBCC)Cystine CrystalsSquamous Epithelial CellsCalcium Phosphate CrystalsiChem VELOCITY The NEW Chemistry StandardThe iChemVELOCITY Urine Chemistry System takes a leap forward with the development of an ascorbic acid test pad to identify possible ascorbic acid interference to insure clinically significant and accurate results. The iChem 100 and the iChem STRIPS , are the perfect fit for a Complete backup solution for the iChemVELOCITY. Fully aligned and fully Proven Technology Providing Quality Results Excellent low-end sensitivity Utilization of ascorbic acid detection to prevent potential interference with key chemistry assaysPRODUCTIVITY Capacity and Ease-of-Use Effortless operation, just load samples, press START and walk away 210 samples per hour Continuous strip loading capability 300 urine chemistry strip load capacity 10,000 Patient record storage capacitiesVALUE Return on Investment Seamless integration with iQ200 ELITE and iQ200 SPRINT Automated Urine Microscopy Systems Maximizes system up-time with the integrated back-up.

10 IChem100 Urine Chemistry System Concordant results with iChem100 and iChemSTRIPS Consolidated Urine Chemistry StripsiChem100 Semi-automated Urine Chemistry SystemThe perfect back up to the iChemVELOCITY Urine Chemistry System or as a stand alone urine chemistry system. Integrates into an iRICELL2000 and iRICELL3000 to provide 1 0 0 Urine Chemistry System The NEW iChemSTRIPS Consolidated Urine Chemistry Strips Works on the iChem100 and doubles as a visual read urine chemistry strip Excellent discrimination between cut-off levels for each chemistry concentration Ascorbic Acid chemistry provides the same inference management and quality results as the iChem VELOCITY Urine Chemistry StripsiChem VELOCITYU rine Chemistry System Contact an Iris Diagnostics Representative for more comprehensive urine testing solutions today!