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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, …
Interference No. 106,132 CVC Substantive Motion 4 ii Appendix 6: Claim Chart Comparing the ’716 Patent’s Claims 2-4, 11, 14, and 21-22 to
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, …
patentdocs.typepad.comJan 11, 2022 · 1 The near-simultaneous results published by these groups confirm that a person of ordinary skill in 2 the art (“POSA”) would have readily understood how to apply CVC’s system in eukaryotic cells. 3 The question posed at the time was not whether CRISPR-Cas9 would function in eukaryotes—it
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, …
patentdocs.typepad.comJan 13, 2022 · Sigma Application 15/456,205, claim 31. CVC Application 15/981,807, claim 156 or Sigma Application 15/456,205, claim 33. 3 This substitution changes Sigma’s half of the count to its involved dependent claim 33, 4 which recites “wherein the guide RNA is a single molecule,” but is otherwise identical to the 5 current Count.
UNITED STATES PATENT AND TRADEMARK OFFICE …
patentdocs.typepad.comUNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF ... Ex. 2468, ¶¶ 277-282; MF14. In the early 2000s, well before 2012, ZFNs had been used for 16 site-specific, programmable gene editing to accomplish genome modifications in eukaryotic cells.
Paper No. Filed February 18, 2022 Filed on behalf of ...
patentdocs.typepad.com12 encompass both single-molecule guide RNA (“sgRNA”) and dual-molecule guide RNA 13 (“dgRNA”), as revealed by CVC’s challenges to Sigma’s sgRNA proofs made by CVC’s 14 exclusive licensee in EPO opposition proceedings. Moreover, Sigma’s more comprehensive
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